Results 61 to 70 of about 21,456 (303)
The Emerging Role(s) for Kisspeptin in Metabolism in Mammals
Frontiers in Endocrinology, 2018 Kisspeptin was initially identified as a metastasis suppressor. Shortly after the initial discovery, a key physiologic role for kisspeptin emerged in the regulation of fertility, with kisspeptin acting as a neurotransmitter via the kisspeptin receptor ...
Andrew Wolfe, Mehboob A. Hussain
doaj +1 more source
Timing of maternal exposure and fetal sex determine the effects of low-level chemical mixture exposure on the fetal neuroendocrine system in sheep [PDF]
, 2016 We have shown that continuous maternal exposure to the complex mixture of environmental chemicals (ECs) found in human biosolids (sewage sludge), disrupts mRNA expression of genes crucial for development and long-term regulation of hypothalamo-pituitary ...
Bellingham, M. +7 more
core +2 more sources
Role of Kisspeptin and Neurokinin B in Puberty in Female Non-Human Primates
Frontiers in Endocrinology, 2018 In human patients, loss-of-function mutations in the genes encoding kisspeptin (KISS1) and neurokinin B (NKB) and their receptors (KISS1R and NK3R, respectively) result in an abnormal timing of puberty or the absence of puberty.
Ei Terasawa +4 more
doaj +1 more source
Fertility & Reproduction, 2023 Background and Aims: Kisspeptin is an emerging biomarker for the discrimination of viable pregnancy. The aim of the study is to determine whether serum kisspeptin can predict the first trimester miscarriage and compare it with serum hCG in the prediction
He Li
doaj +1 more source
Effects of Kisspeptin Administration in Women With Hypoactive Sexual Desire Disorder
JAMA Network Open, 2022 Key Points Question Does kisspeptin administration improve sexual and attraction brain processing in women with hypoactive sexual desire disorder? Findings In this randomized clinical trial including 32 premenopausal women with hypoactive sexual desire ...
L. Thurston +15 more
semanticscholar +1 more source
Effects of Selective Deletion of Tyrosine Hydroxylase from Kisspeptin Cells on Puberty and Reproduction in Male and Female Mice. [PDF]
, 2017 The neuropeptide kisspeptin, encoded by Kiss1, regulates reproduction by stimulating GnRH secretion. Kiss1-syntheizing neurons reside primarily in the hypothalamic anteroventral periventricular (AVPV/PeN) and arcuate (ARC) nuclei.
Chahal, Navi +6 more
core +1 more source
Journal of neuroendocrinology, 2022 Kisspeptin neurons in the arcuate nucleus of the hypothalamus generate gonadotrophin‐releasing hormone (GnRH) pulses, and act as critical initiators of functional gonadotrophin secretion and reproductive competency.
G. Lass +11 more
semanticscholar +1 more source
Distribution and regulation of gonadotropin-releasing hormone, kisspeptin, RF-amide related peptide-3, and dynorphin in the bovine hypothalamus [PDF]
PeerJ, 2016 Recent work has led to the hypothesis that kisspeptin/neurokinin B/dynorphin (KNDy) neurons in the arcuate nucleus (ARC) play a key role in gonadotropin-releasing hormone (GnRH) pulse generation and gonadal steroid feedback, with kisspeptin driving GnRH ...
Valeria M. Tanco +5 more
doaj +2 more sources
Frontiers in Endocrinology, 2021 Increasing evidence accumulated during the past two decades has demonstrated that the then-novel kisspeptin, which was discovered in 2001, the known neuropeptides neurokinin B and dynorphin A, which were discovered in 1983 and 1979, respectively, and ...
Y. Uenoyama +4 more
semanticscholar +1 more source
Kisspeptin as a Behavioral Hormone
Seminars in Reproductive Medicine, 2019 AbstractSuccessful reproduction is dependent not only on hormonal endocrine responses but also on suitable partner selection, copulatory acts, as well as associated emotional, behavioral, and cognitive processes many of which are supported by the limbic system.
Mills, EGA, O'Byrne, KT, Comninos, AN
openaire +4 more sources