Results 61 to 70 of about 16,602 (265)
Morphine Attenuates Testosterone Response to Central Injection of Kisspeptin in Male Rats [PDF]
International Journal of Fertility and Sterility, 2014 Background Kisspeptin and naloxone stimulate the reproductive axis while morphine inhibits its function. We have investigated the effect of central injection of kisspeptin-10 on mean plasma testosterone concentration in morphine or naloxone pretreated
Fariba Mahmoudi +2 more
doaj
Lower circulating kisspeptin and primary hypogonadism in men with type 2 diabetes
Endocrinology, Diabetes & Metabolism, 2019 Introduction Kisspeptin influence on male androgens is partially understood. We aimed to evaluate serum concentrations of kisspeptin among Ghanaian men with type 2 diabetes and to identify related factors that may contribute to altering circulating ...
Henry Asare‐Anane +6 more
doaj +1 more source
Animals, 2022 The release of reproductive hormones in the hypothalamic–pituitary–gonadal (HPG) axis is regulated by its upstream regulator, kisspeptin, and influenced by external stresses, including heat stress.
Hwan-Deuk Kim +9 more
doaj +1 more source
Gynecological Endocrinology, 2023 Introduction The purpose of this study was to determine the association between kisspeptin levels and obesity in patients with polycystic ovary syndrome (PCOS) or in healthy controls and to explore the correlation between levels of kisspeptin and various
Meixiu Gao +5 more
doaj +1 more source
Cre/lox generation of a novel whole-body Kiss1r KO mouse line recapitulates a hypogonadal, obese, and metabolically-impaired phenotype. [PDF]
, 2019 Kisspeptin and its receptor, Kiss1r, act centrally to stimulate reproduction. Recent evidence indicates that kisspeptin is also important for body weight and metabolism, as whole-body Kiss1r KO mice, developed with gene trap technology, display obesity ...
Kauffman, Alexander S +4 more
core +1 more source
Afferent Neuronal Control of Type-I Gonadotropin Releasing Hormone Neurons in the Human. [PDF]
, 2013 Understanding the regulation of the human menstrual cycle represents an important ultimate challenge of reproductive neuroendocrine research. However, direct translation of information from laboratory animal experiments to the human is often complicated ...
Hrabovszky, Erik, Liposits, Zsolt
core +1 more source
Potential roles for the kisspeptin/kisspeptin receptor system in implantation and placentation [PDF]
Human Reproduction Update, 2018 Initially identified as suppressors of metastasis in various types of cancer, kisspeptins are a family of neuropeptides that are key regulators of the mammalian reproductive axis. Accumulating evidence has shown that kisspeptin is able to control both the pulsatile and surge GnRH release, playing fundamental roles in female reproduction, which include ...
Kai-Lun Hu +5 more
openaire +3 more sources
Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel +5 more
wiley +1 more source
The evolution and variety of RFamide-type neuropeptides: insights from deuterostomian invertebrates [PDF]
, 2014 Five families of neuropeptides that have a C-terminal RFamide motif have been identified in vertebrates: (1) gonadotropin-inhibitory hormone (GnIH), (2) neuropeptide FF (NPFF), (3) pyroglutamylated RFamide peptide (QRFP), (4) prolactin-releasing peptide (
Elphick, MR, Mirabeau, O
core +1 more source
Frontiers in Neuroendocrinology, 2022 Kisspeptin, encoded by the KISS1 gene, was first discovered as a potential metastasis suppressor gene. The prepro-kisspeptin precursor is cleaved into shorter mature bioactive peptides of varying sizes that bind to the G protein-coupled receptor GPR54 (=KISS1R).
Mageswary Sivalingam, Ishwar S. Parhar
openaire +3 more sources