Results 171 to 180 of about 12,544 (218)

Dissecting the Metabolic Costs of Uphill and Downhill Walking

Scandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 11, November 2026.
ABSTRACT Work‐ and collision‐based models of locomotion relate the body's mechanical work requirements to metabolic energy expenditure at a system level, but do not capture the underlying force and work demands of muscle that drive energy use. Energy is liberated as heat to activate muscle and maintain force production (“force‐related costs”) and as ...
Luke N. Jessup, Luke A. Kelly, Andrew G. Cresswell, Glen A. Lichtwark   +3 more
wiley   +1 more source

Lactate and lactylation in sepsis: regulation of immune-metabolic crosstalk and organ injury. [PDF]

Front Immunol
Li Z, Gu WJ, Li T, Dai X, Duan XJ, Yang F, Yin HY, Zhang Z, Li P.   +8 more
europepmc   +1 more source

Protein lactylation in myocardial ischemia-reperfusion injury: mechanisms and therapeutic potential. [PDF]

Front Cardiovasc Med
Zhan H, Li D, He J, Hu Y, Jiang W, Zhang J, Chen W, Xu W.   +7 more
europepmc   +1 more source

Integrative multi-omics of esophageal squamous cell carcinoma reveals immune alterations and lactylation-driven mechanisms in metastatic progression. [PDF]

Mol Cancer
Pang Y, Gao Y, Liu G, Zhao J, Lin H, Wang Y, Xin L, Wang W, Bian Y, Jiao Y, Li Q, Li Z, Li Z, Huang H, Wang L.   +14 more
europepmc   +1 more source

Resolution of Refractory Chylous Effusions With Targeted MEK Inhibition in NRAS Q61R-Driven Kaposiform Lymphangiomatosis: A Case Report. [PDF]

Case Rep Pediatr
Brown G, McNab S, Keogh S, Massie J, Eastaugh L, Pathmanathan L, Bertinetti M, Sullivan M, Orme L, Cloney T, Brown NJ, Tan TY, Quin R, Pertile M, Moon A, Bekhit E, Penington T.   +16 more
europepmc   +1 more source

Protein lactylation in cancer: principles, programmes and therapeutic opportunities. [PDF]

Mol Cancer
Bu X, Yu X, Wang J, Peng M, Su M, Tang Y, Jiang J, Luo X, Xia M, Yi Y, Jiang X.   +10 more
europepmc   +1 more source

Training PBertKla on an Integrated Multi-Source Dataset with a Machine-Learning Layer for Lysine Lactylation Site Prediction. [PDF]

Int J Mol Sci
Jin SB, Park J, Lee SD, Han JH, Myung SH, Park K, Yun J.   +6 more
europepmc   +1 more source

Data Resources and Computational Methods for Lactylation Site Prediction: A Mini-Review. [PDF]

Int J Mol Sci
Wang C, Pan Y, Wu Y, Wu X.
europepmc   +1 more source

Identification of protein lysine lactylation and potential targets in esophageal squamous cell carcinoma. [PDF]

Transl Cancer Res
Zhang H, Yan X, Xi L, Chen S, Shang Q, Chen LQ, Wang WP.   +6 more
europepmc   +1 more source