Results 51 to 60 of about 11,628 (203)

microRNA-26a shuttled by extracellular vesicles secreted from adipose-derived mesenchymal stem cells reduce neuronal damage through KLF9-mediated regulation of TRAF2/KLF2 axis

Adipocyte, 2021
Extracellular vesicles (EVs) are nano-sized vesicles secreted actively by numeorus cells and have fundamental roles in intercellular communication through shuttling functional RNAs.
Zixin Hou, Ji Chen, Huan Yang, Xiaoling Hu, Fengrui Yang   +4 more
doaj   +1 more source

Expression of KLF2 in BOECs.

, 2012
(A) Immunofluorescent analysis of mock- and KLF2-transduced BOECs. Cells were immunostained for CD31 (red) and KLF2 (green); nuclei were stained using DAPI (blue).
Ruben Bierings (159083), Bieuwke S. Dragt (159089), Ellen L. van Agtmaal (159077), Jan Voorberg (159111), Mar Fernandez-Borja (159099), Anton J. G. Horrevoets (159105), Thomas A. Leyen (159093)   +6 more
core   +1 more source

Krüppel-like factor 2 promotes liver steatosis through upregulation of CD36

Journal of Lipid Research, 2014
The Krppel-like factor (KLF) family of transcription factors regulates diverse biological processes that include proliferation, differentiation, apoptosis, development, and responses to external stress.
Jin-Lian Chen, Xiao-Jie Lu, Kai-Lin Zou, Kun Ye   +3 more
doaj   +1 more source

KLF2 dependency of AQP1 expression.

, 2016
(A, B) Expression of KLF2 was induced in HUVEC by laminar flow (shear), lentiviral transduction (KLF2) or incubation with atorvastatin (statin). mRNA levels were determined by semi-quantitative RT-PCR for AQP1 (A) and eNOS (B), normalized to P0 and shown
Ruud D. Fontijn (725564), Oscar L. Volger (804629), Anuradha Doddaballapur (840992), Thomas Leyen (840993), Josefien M. Baggen (725563), Tineke C. van der Pouw-Kraan (840991), Anton J. G. Horrevoets (159105), Reinier A. Boon (840994)   +7 more
core   +1 more source

KLF2 regulates activated CD4 T cell differentiation

, 2018
T follicular helper (Tfh) cells are essential for efficient B cell responses, yet the factors that regulate differentiation of this CD4(+) T cell subset are incompletely understood.
Malhotra, D, Jameson, SC, Lee, YJ, Lee, JY, Taylor, JJ, Hogquist, KA, Skon, CN, Rosenfeld, MG, Oh, S, Jenkins, MK   +9 more
core   +1 more source

Krüppel-like transcription factors KLF1 and KLF2 have unique and coordinate roles in regulating embryonic erythroid precursor maturation

Haematologica, 2014
The Krüppel-like transcription factors KLF1 and KLF2 are essential for embryonic erythropoiesis. They can partially compensate for each other during mouse development, and coordinately regulate numerous erythroid genes, including the β-like globins ...
Divya S. Vinjamur, Kristen J. Wade, Safa F. Mohamad, Jack L. Haar, Stephen T. Sawyer, Joyce A. Lloyd   +5 more
doaj   +1 more source

Dual Regulatory Functions of Classical Zinc Finger Clusters from Myeloid Zinc Finger‐1

Chemistry – A European Journal, EarlyView.
The classical zinc finger (ZF) protein MZF1 uses two ZF clusters to achieve metal‐dependent and gene‐specific promoter recognition. The differential redox stability and modular utilization of the two ZF clusters enable MZF1 to regulate cerebrovascular, neuronal, and cancer‐related transcriptional programs.
Yunha Hwang, Yerim Park, Nohwan Park, Heeju Noh, Hyun Goo Kang, Seung Jae Lee   +5 more
wiley   +1 more source

Papel del factor de transcripción Kruppel-like factor 2 en la disfunción endotelial hepática asociada a la hipertensión portal y al daño por isquemia y reperfusión [PDF]

, 2011
El endotelio disfuncional presenta, entre otras caracteristicas, alteración en los mecanismos de vasodilatación, complicaciones trombóticas, disminución de la resistencia al estrés oxidativo, aumento de la expresión de moléculas de adhesión y de la ...
Russo, Lucia
core  

miR‐92a‐3p promotes breast cancer proliferation by regulating the KLF2/BIRC5 axis

Thoracic Cancer, 2022
Background Breast cancer remains the most common malignancy in females around the world. Recently, a growing number of studies have focused on gene dysregulation.
Zhi‐Hao Yu, Zhao‐Hui Chen, Guang‐Lei Zhou, Xue‐Jie Zhou, Hai‐Yan Ma, Yue Yu, Xin Wang, Xu‐Chen Cao   +7 more
doaj   +1 more source

Expanded Hemodialysis ameliorates uremia-induced impairment of vasculoprotective KLF2 and concomitant proinflammatory priming of endothelial cells through an ERK/AP1/cFOS-dependent mechanism

Frontiers in Immunology, 2023
AimsExpanded hemodialysis (HDx) therapy with improved molecular cut-off dialyzers exerts beneficial effects on lowering uremia-associated chronic systemic microinflammation, a driver of endothelial dysfunction and cardiovascular disease (CVD) in ...
Hongfan Zhao, Dashan Wu, Michael Adu Gyamfi, Pinchao Wang, Christian Luecht, Anna Maria Pfefferkorn, Muhammad Imtiaz Ashraf, Julian Kamhieh-Milz, Janusz Witowski, Duska Dragun, Klemens Budde, Ralf Schindler, Daniel Zickler, Guido Moll, Guido Moll, Rusan Catar   +15 more
doaj   +1 more source