Results 231 to 240 of about 758,384 (303)

p2rx3 Knockout Mice Have Altered Energy Metabolism in Hippocampal Neurons. [PDF]

Acta Naturae
Zelentsova AS, Pokrovskii MV, Patrakhanov EA, Shmigerova VS, Skorkina MY, Deykin AV.   +5 more
europepmc   +1 more source

Artifact‐Minimizing Ultrathin Transparent Electrodes Fabricated via iCVD for In Vivo Optogenetic Stimulation and Neural Signal Monitoring of Primary Visual Cortex

Advanced Functional Materials, EarlyView.
We present ultrathin flexible transparent electrodes through iCVD‐enabled molecular control of 10 nm gold films on poly(dimethylaminomethylstyrene). In vivo validation demonstrated photoelectric artifact reduction vs. opaque electrodes and preservation of natural neural dynamics.
Tae Jin Mun, Minju Kim, Chaesung Kim, Yunyoung Choi, In‐Yeop Baek, Younghak Cho, Gyeongyong Lee, Yerim Jang, Min‐Ho Nam, Wonryung Lee, Maesoon Im, Hyejeong Seong   +11 more
wiley   +1 more source

Early Supplementation with Branched-Chain Amino Acids Ameliorates Lipid Retention in Aortic Valves of ApoE-Knockout Mice. [PDF]

Int J Mol Sci
Shishkova D, Kanonykina A, Kondratiev E, Tyurina A, Morozova A, Poddubnyak A, Sinitskaya A, Sinitsky M, Markova V, Lazebnaya A, Bogdanov L, Stepanov A, Agalaryan S, Kutikhin A.   +13 more
europepmc   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Differences between therapeutic mechanisms of resmetirom and semaglutide against MASH in western diet-fed MC4R-knockout mice. [PDF]

Sci Rep
Sugawara T, Hitaka K, Matsumoto M, Nakamura S, Kobayashi R, Kandori H, Nio Y.   +6 more
europepmc   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Characterization of Neurensin-2 knockout mice: insights into stress-resilience mechanisms. [PDF]

Transl Psychiatry
Hovav HC, Kashi OY, Abu Ghanem Y, Stochinsky N, Agbariya L, Yehuda H, Weitz-Aviv M, Baraghithy S, Tam J, Yaka R, Umschweif G.   +10 more
europepmc   +1 more source

Establishing a Model Precursor System: Over a Decade of Research on Carbon Dots from the Citric Acid‐Urea System

Advanced Functional Materials, EarlyView.
The citric acid/urea (CA‐Urea) precursor system offers a versatile, scalable route to carbon dots with tunable luminescence and multifunctionality. Mechanistic insights into precursor chemistry and reaction parameters have enabled doping, surface modification, and hybridization strategies, yielding CDs for luminescent devices, sensing, catalysis ...
Yupeng Liu, Zhiqi Cai, Xiangxin Sun, Hanyi Zhang, Yiming Hao, Jun Wu, Zekun Yan, Xue Wu, Yiqi Liang, Liming Wang, Songnan Qu   +10 more
wiley   +1 more source

Analysis of knockout mice reveals critical female-specific roles for the Hippo pathway component PTPN14. [PDF]

Genes Dev
McCrea EM, Makrides N, Tabata T, Reineking W, Vilches-Moure JG, Wang M, Lake JS, Vogel H, Howitt B, Zhang X, Attardi LD.   +10 more
europepmc   +1 more source

Bioactive Conductive Ti3C2Tx‐Ce Hydrogel Facilitates Spinal Cord Injury Repair Through ROS Scavenging and Mitochondrial Regulation

Advanced Functional Materials, EarlyView.
Bioactive conductive Ti3C2Tx‐Ce hydrogels with with scavenging ROS and alleviating neuronal mitochondrial dysfunction are exploited for SCI treatment. This functionality is attributed to interfacial activation modification of Ti3C2Tx with Ce3+ ions to in‐situ form Ce(OH)x‐mediated protective layer, which is beneficial to enabling stable intracellular ...
Weikang Wang, Qing Liu, Ang Lv, Yabin Lin, Jiawei Chen, Ning Ding, Chunlei Zhang, Shuai Zhou, Bo Yuan, Weiwei Zhao, Liming Li, Luping Zhang, Fei Huang   +12 more
wiley   +1 more source