Results 231 to 240 of about 777,239 (352)

Behavioral Balance in Tryptophan Turmoil: Regional Metabolic Rewiring in Kynurenine Aminotransferase II Knockout Mice. [PDF]

open access: yesCells
Szabó Á   +15 more
europepmc   +1 more source

Generation and characterization of calsyntenin triple knockout mice

open access: green, 2017
Mori Keita   +6 more
openalex   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Integrated multi‑omics analysis of liver metabolic dysregulation in ACE2 knockout mice. [PDF]

open access: yesInt J Mol Med
Xiao S   +8 more
europepmc   +1 more source

Effect of human scavenger receptor class A overexpression in bone marrow-derived cells on lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knockout mice [PDF]

open access: hybrid, 2000
Nicole Herijgers   +6 more
openalex   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

Wheat-Based Protein Slows Disease Progression in Pkd1 Knockout Mice. [PDF]

open access: yesFunction (Oxf)
Sedaka R   +14 more
europepmc   +1 more source

Effects of Kv1.3 knockout on pyramidal neuron excitability and synaptic plasticity in piriform cortex of mice [PDF]

open access: green
Yongsheng Zhou   +10 more
openalex   +1 more source

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