Results 51 to 60 of about 34,694 (215)

Emergence of KPC-2-Producing Salmonella enterica Serotype Schwarzengrund in Argentina [PDF]

Antimicrobial Agents and Chemotherapy, 2014
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Jure, M A, Duprilot, M, Musa, H E, López, C, de Castillo, Marta C, Weill, François-Xavier, Arlet, G, Decré, D   +7 more
openaire   +2 more sources

Identification of Two Novel Carbapenemase-Encoding Hybrid Plasmids Harboring blaNDM-5 and blaKPC-2 in a Clinical ST11-KL47 Klebsiella pneumoniae

Infection and Drug Resistance, 2023
Weiqiang Xiao,1,* Xiaokun Wang,1,* Yuanye Qu,1 Mingyue Sun,1 Yanmin Chang,1 Wenjiao Li,1 Yong Shen,1,2 Xiufang Shi,3 Min Jing,1 Qingxia Xu1,4 1Department of Clinical Laboratory, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou ...
Xiao W, Wang X, Qu Y, Sun M, Chang Y, Li W, Shen Y, Shi X, Jing M, Xu Q   +9 more
doaj  

Elimination of bla KPC−2-mediated carbapenem resistance in Escherichia coli by CRISPR-Cas9 system

BMC Microbiology, 2023
Objective The purpose of this study is to re-sensitive bacteria to carbapenemases and reduce the transmission of the bla KPC−2 gene by curing the bla KPC−2-harboring plasmid of carbapenem-resistant using the CRISPR-Cas9 system.
Shuan Tao, Huimin Chen, Na Li, Yewei Fang, He Zhang, Yao Xu, Luyan Chen, Wei Liang   +7 more
doaj   +1 more source

The Panchromatic Starburst Intensity Limit At Low And High Redshift [PDF]

, 1997
The integrated bolometric effective surface brightness S_e distributions of starbursts are investigated for samples observed in 1. the rest frame ultraviolet (UV), 2. the far-infrared and H-alpha, and 3. 21cm radio continuum emission.
Heckman, Timothy M., Lehnert, Matthew D., Leitherer, Claus, Lowenthal, James, Meurer, Gerhardt R.   +4 more
core   +4 more sources

Defining the architecture of KPC-2 Carbapenemase: identifying allosteric networks to fight antibiotics resistance [PDF]

Scientific Reports, 2018
AbstractThe rise of multi-drug resistance in bacterial pathogens is one of the grand challenges facing medical science. A major concern is the speed of development of β-lactamase-mediated resistance in Gram-negative species, thus putting at risk the efficacy of the most recently approved antibiotics and inhibitors, including carbapenems and avibactam ...
Ioannis Galdadas, Silvia Lovera, Guillermo Pérez-Hernández, Melissa D. Barnes, Jess Healy, Hamidreza Afsharikho, Neil Woodford, Robert A. Bonomo, Francesco L. Gervasio, Shozeb Haider   +9 more
openaire   +3 more sources

The effect of Lactobacillus with prebiotics on KPC-2-producing Klebsiella pneumoniae

Frontiers in Microbiology, 2022
ObjectivesThis study investigated the inhibitory effect ofLactobacillusspp. with prebiotics againstKlebsiella pneumoniaecarbapenemase-2 (KPC-2)-producingKlebsiella pneumoniaeusing bothin vitroexperiments and animal models.MethodsThirty-threeLactobacillusspp.
Hung-Jen Tang, Hung-Jen Tang, Chi-Chung Chen, Ying-Chen Lu, Hui-Ling Huang, Hung-Jui Chen, Yin-Ching Chuang, Chih-Cheng Lai, Chien-Ming Chao   +8 more
openaire   +3 more sources

Inter-hospital outbreak of Klebsiella pneumoniae producing KPC-2 carbapenemase in Ireland [PDF]

Journal of Antimicrobial Chemotherapy, 2012
To describe an outbreak of KPC-2-producing Klebsiella pneumoniae with inter-hospital spread and measures taken to control transmission. Between January and March 2011, 13 K. pneumoniae isolates were collected from nine patients at hospital A and two patients at hospital B.
Morris, D., Boyle, F., Morris, C., Condon, I., Delannoy-Vieillard, A.-S., Power, L., Khan, A., Morris-Downes, M., Finnegan, C., Powell, J., Monahan, R., Burns, K., O'Connell, N., Boyle, L., O'Gorman, A., Humphreys, H., Brisse, S., Turton, J., Woodford, N., Cormican, M.   +19 more
openaire   +3 more sources

Shift in the Dominant Sequence Type of Carbapenem-Resistant Klebsiella pneumoniae Bloodstream Infection from ST11 to ST15 at a Medical Center in Northeast China, 2015–2020

Infection and Drug Resistance, 2021
Jingjing Chen,1– 3 Chang Hu,1– 3 Ruixuan Wang,1– 3 Fushun Li,1– 3 Guoquan Sun,1– 3 Min Yang,1– 3 Yunzhuo Chu1– 3 1Department of Laboratory Medicine, The First Affiliated Hospital of China Medical University ...
Chen J, Hu C, Wang R, Li F, Sun G, Yang M, Chu Y   +6 more
doaj  

In vivo Selection of Imipenem Resistance Among Ceftazidime-Avibactam-Resistant, Imipenem-Susceptible Klebsiella pneumoniae Isolate With KPC-33 Carbapenemase

Frontiers in Microbiology, 2021
We describe in vivo evolution of carbapenem and ceftazidime-avibactam resistance by analyzing four longitudinal Klebsiella pneumoniae clinical isolates from a patient with pneumonia following antimicrobial treatment.
Chunlei Wang, Chunlei Wang, Chunlei Wang, Chunlei Wang, Jiankang Zhao, Jiankang Zhao, Jiankang Zhao, Jiankang Zhao, Zhibo Liu, Zhibo Liu, Zhibo Liu, Aihua Sun, Aihua Sun, Aihua Sun, Lingxiao Sun, Lingxiao Sun, Lingxiao Sun, Lingxiao Sun, Binbin Li, Binbin Li, Binbin Li, Binbin Li, Binghuai Lu, Binghuai Lu, Binghuai Lu, Binghuai Lu, Yingmei Liu, Yingmei Liu, Yingmei Liu, Yingmei Liu, Bin Cao, Bin Cao, Bin Cao, Bin Cao   +33 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source