Results 61 to 70 of about 34,694 (215)
Deep into the structure of the first galaxies: SERRA views [PDF]
We study the formation and evolution of a sample of Lyman Break Galaxies in the Epoch of Reionization by using high-resolution ($\sim 10 \,{\rm pc}$), cosmological zoom-in simulations part of the SERRA suite.
Behrens, C. +8 more
core +3 more sources
First report of Klebsiella quasipneumoniae harboring bla KPC-2 in Saudi Arabia
Background Nosocomial infections caused by multi-drug resistant Enterobacteriaceae are a global public health threat that ought to be promptly identified, reported, and addressed accurately.
Sharif Hala +10 more
doaj +1 more source
Alterations of the PALB2 tumor suppressor gene have been identified in familial breast, ovarian and pancreatic cancer cases. PALB2 cooperates with BRCA1/2 proteins through physical interaction in initiation of homologous recombination, in maintenance of ...
Dongju Park +8 more
doaj +1 more source
Background Despite the global prevalence of Klebsiella pneumoniae Carbapenemase (KPC)-type class A β-lactamases, occurrences of KPC-3-producing isolates in China remain infrequent. This study aims to explore the emergence, antibiotic resistance profiles,
Haoyu Ge +9 more
doaj +1 more source
A novel Klebsiella pneumoniae carbapenemase (KPC) variant, KPC-93, was identified in two Klebsiella pneumoniae clinical isolates from a patient from China treated with ceftazidime-avibactam.
Yuchen Wu +7 more
doaj +1 more source
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade +19 more
wiley +1 more source
Calibrating the relation of low-frequency radio continuum to star formation rate at 1 kpc scale with LOFAR [PDF]
9 figures, 6 tables and 17 pages. This paper is part of the LOFAR surveys data release 1 and has been accepted for publication in a special edition of A&A that will appear in Feb 2019, volume 622.
Basu, A. +18 more
core +7 more sources
KPC-2 producing ST101 Klebsiella pneumoniae from bloodstream infection in India
This study characterizes KPC-2 producing Klebsiella pneumoniae belonging to ST101. Whole genome sequencing using the Ion Torrent PGM platform with 400 bp chemistry was performed. blaKPC-2 was found on an IncFIIK plasmid associated with ISKpn6 and ISKpn7 without Tn4401. This is the first report of KPC-2 K. pneumoniae from bacteremia in India.
Chaitra, Shankar +3 more
openaire +2 more sources
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
Insights into a Novel blaKPC-2-Encoding IncP-6 Plasmid Reveal Carbapenem-Resistance Circulation in Several Enterobacteriaceae Species from Wastewater and a Hospital Source in Spain [PDF]
Untreated wastewater, particularly from hospitals and other healthcare facilities, is considered to be a reservoir for multidrug-resistant bacteria.
Cantón, Rafael +8 more
core +1 more source

