Results 31 to 40 of about 17,687,028 (211)

Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Hong Kong [PDF]

International Journal of Antimicrobial Agents, 2011
postprint
Ho, PL, Tse, CWS, Lai, EL, Lo, WU, Chow, KH   +4 more
openaire   +4 more sources

First Description of KPC-2-Producing Klebsiella oxytoca in Brazil [PDF]

Antimicrobial Agents and Chemotherapy, 2013
ABSTRACT The present work reports the detection of the first case of nosocomial Klebsiella oxytoca producing class A carbapenemase KPC-2 in Brazil. The isolate KPN106 carried a 65-kb IncW-type plasmid that harbors the bla KPC gene and Tn 4401 b ...
Almeida, Anna C. S., Cavalcanti, Felipe L. S., Martins, Willames M. B., Vilela, Marinalda A., Gales, Ana C. UNIFESP, Morais Junior, Marcos A., Morais, Marcia M. C.   +6 more
openaire   +3 more sources

KPC-2 carbapenemase-producing Pseudomonas aeruginosa reaching Germany [PDF]

Journal of Antimicrobial Chemotherapy, 2018
Antimicrobial resistance due to carbapenemase expression poses a worldwide threat in healthcare. Inter-genus exchange of genetic information is of utmost importance in this context.Here, to the best of our knowledge, we describe the first detection and characterization of a KPC-2-producing Pseudomonas aeruginosa in Germany.Characterization of the ...
Jürgen Benjamin Hagemann, Niels Pfennigwerth, Sören G Gatermann, Heike von Baum, Andreas Essig   +4 more
openaire   +2 more sources

Variants of β-Lactamase KPC-2 That Are Resistant to Inhibition by Avibactam [PDF]

Antimicrobial Agents and Chemotherapy, 2015
ABSTRACT KPC-2 is the most prevalent class A carbapenemase in the world. Previously, KPC-2 was shown to hydrolyze the β-lactamase inhibitors clavulanic acid, sulbactam, and tazobactam. In addition, substitutions at amino acid position R220 in the KPC-2 β-lactamase increased resistance to clavulanic acid.
Krisztina M, Papp-Wallace, Marisa L, Winkler, Magdalena A, Taracila, Robert A, Bonomo   +3 more
openaire   +2 more sources

Importation of KPC-2-producing Escherichia coli from India [PDF]

Journal of Antimicrobial Chemotherapy, 2011
Sir, The production of carbapenem-hydrolysing b-lactamases is increasingly reported in Enterobacteriaceae. Among the different types of carbapenemases, the emergence of the Ambler class A KPC-type b-lactamases is of great concern, since those enzymes hydrolyse all b-lactams with the exception of cephamycins.
Potron, A., Poirel, L., Verdavaine, D., Nordmann, P.   +3 more
openaire   +2 more sources

A multidisciplinary approach to the design of novel inhibitors for KPC-2

, 2017
Background. The emergence and dissemination of multi drug resistant (MDR) Gram-negative pathogens resistant to all available antibiotics poses a significant threat in clinical therapy. Among them, Klebsiella Pneumoniae clinical isolates overexpressing KPC-2 carbapenemase are the most worrisome, extending bacterial resistance to last resort carbapenems.
Celenza, Giuseppe, Bellio, Pierangelo, LINCIANO, PASQUALE, Perilli, Mariagrazia, Cendron, Laura, TONDI, Donatella   +5 more
openaire   +2 more sources

Characterization of Carbapenem-Resistant Klebsiella pneumoniae ST15 Clone Coproducing KPC-2, CTX-M-15 and SHV-28 Spread in an Intensive Care Unit of a Tertiary Hospital

Infection and Drug Resistance, 2021
Yaping Han,1,2 Lei Huang,1,2 Chengcheng Liu,1,2 Xu Huang,3 Ruiying Zheng,1,2 Yanfei Lu,1,2 Wenying Xia,1,2 Fang Ni,1,2 Yaning Mei,1,2 Genyan Liu1,2 1Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing ...
Han Y, Huang L, Liu C, Huang X, Zheng R, Lu Y, Xia W, Ni F, Mei Y, Liu G   +9 more
doaj  

Arrival of Klebsiella pneumoniae carbapenemase (KPC)-2 in Taiwan [PDF]

Journal of Antimicrobial Chemotherapy, 2011
Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Clinical Laboratory Sciences and Medical Biotechnology, National ...
K.-P. Chung, S.-P. Tseng, Y.-T. Huang, T.-H. Tsai, L.-J. Teng, P.-R. Hsueh   +5 more
openaire   +1 more source

Characterization of Hypervirulent and Carbapenem-Resistant K. pneumoniae Isolated from Neurological Patients

Infection and Drug Resistance, 2023
Qingping Zhou,1,* Chunyang Wu,2,* Peiyao Zhou,3 Ji Zhang,1 Zhanghua Xiong,4 Ying Zhou,5 Fangyou Yu5 1Department of Neurology, Jiangxi Provincial People’s Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, 330006 ...
Zhou Q, Wu C, Zhou P, Zhang J, Xiong Z, Zhou Y, Yu F   +6 more
doaj  

KPC-derived organoid tumor histopathology features.

, 2020
KPC-derived organoid tumor stained for hyaluronic acid (A), pimonidazole (B), collagen (green) and Meca32 (red) (C). Co-staining of pimonidazole (green) and Meca-32 (red) (D) showing vessels present in both oxic and hypoxic tissue. Black scale bar = 5 mm.
John L. Humm (8720559), Kenneth H. Yu (1266099), James Russell (326068), Isabella O’Donoghue (8720556), Nagavarakishore Pillarsetty (2185546), Kishore Gangangari (5696168), Louise M. Fanchon (8720553)   +6 more
core   +1 more source