Results 11 to 20 of about 34,694 (215)

Characterization of Corosolic Acid as a KPC-2 Inhibitor That Increases the Susceptibility of KPC-2-Positive Bacteria to Carbapenems [PDF]

Frontiers in Pharmacology, 2020
The emergence of KPC-producing Gram-negative bacteria in clinical practice highlights the need to search for novel antimicrobials and new anti-infection strategies. In this study, we constructed a laboratory KPC-2-positive strain, E.
Yonglin Zhou, Yonglin Zhou, Xiaohong Lv, Meishan Chen, Yan Guo, Rui Ding, Bin Liu, Xuming Deng, Xuming Deng, Jianfeng Wang, Jianfeng Wang   +10 more
doaj   +3 more sources

KPC-2-NDM-1-producing Serratia marcescens: first description in Peru

New Microbes and New Infections, 2022
Two clonal extensively-resistant S. marcescens were isolated in Peru. The presence and transferability of extended-spectrum β-lactamases and IMP, KPC, NDM, OXA-48 and VIM were determined.
Barbara Ymaña, Nestor Luque, Maria J. Pons, Joaquim Ruiz   +3 more
doaj   +3 more sources

Constraining Radio Emission from Magnetars [PDF]

, 2011
We report on radio observations of five magnetars and two magnetar candidates carried out at 1950 MHz with the Green Bank Telescope in 2006-2007. The data from these observations were searched for periodic emission and bright single pulses.
Burgay, Camilo, Camilo, Camilo, Cordes, Cordes, Crawford, D. J. Champion, Dall'Osso, Dib, Dib, Dib, Durant, Gaensler, Gavriil, Gavriil, Green, Haslam, Holland, J. W. T. Hessels, Kaspi, Kogut, Kondratiev, Kouveliotou, Levin, Lorimer, Lorimer, Lorimer, Manchester, Morozova, P. Lazarus, R. Dib, Ransom, Tam, Tian, Torii, V. M. Kaspi, van der Horst, van der Horst, Vasisht, Woods   +40 more
core   +10 more sources

KPC-2 carbapenemase-producing Pseudomonas aeruginosa reaching Germany [PDF]

Journal of Antimicrobial Chemotherapy, 2018
Antimicrobial resistance due to carbapenemase expression poses a worldwide threat in healthcare. Inter-genus exchange of genetic information is of utmost importance in this context.Here, to the best of our knowledge, we describe the first detection and characterization of a KPC-2-producing Pseudomonas aeruginosa in Germany.Characterization of the ...
Jürgen Benjamin Hagemann, Niels Pfennigwerth, Sören G Gatermann, Heike von Baum, Andreas Essig   +4 more
openaire   +2 more sources

Importation of KPC-2-producing Escherichia coli from India [PDF]

Journal of Antimicrobial Chemotherapy, 2011
Sir, The production of carbapenem-hydrolysing b-lactamases is increasingly reported in Enterobacteriaceae. Among the different types of carbapenemases, the emergence of the Ambler class A KPC-type b-lactamases is of great concern, since those enzymes hydrolyse all b-lactams with the exception of cephamycins.
Potron, A., Poirel, L., Verdavaine, D., Nordmann, P.   +3 more
openaire   +2 more sources

Cyclic boronates as versatile scaffolds for KPC-2 β-lactamase inhibition [PDF]

RSC Medicinal Chemistry, 2020
Mono- (vaborbactam) and bi-cyclic (taniborbactam) boronate inhibitors bind KPC-2 similarly, but the latter is essentially irreversible.
Catherine L. Tooke, Philip Hinchliffe, Alen Krajnc, Adrian J. Mulholland, Jürgen Brem, Christopher J. Schofield, James Spencer   +6 more
openaire   +5 more sources

First Description of KPC-2-Producing Klebsiella oxytoca in Brazil [PDF]

Antimicrobial Agents and Chemotherapy, 2013
ABSTRACT The present work reports the detection of the first case of nosocomial Klebsiella oxytoca producing class A carbapenemase KPC-2 in Brazil. The isolate KPN106 carried a 65-kb IncW-type plasmid that harbors the bla KPC gene and Tn 4401 b ...
Almeida, Anna C. S., Cavalcanti, Felipe L. S., Martins, Willames M. B., Vilela, Marinalda A., Gales, Ana C. UNIFESP, Morais Junior, Marcos A., Morais, Marcia M. C.   +6 more
openaire   +3 more sources

First Description of KPC-2-Producing Pseudomonas putida in Brazil [PDF]

Antimicrobial Agents and Chemotherapy, 2012
ABSTRACT This work reports the identification of the first case of a KΡC-2-producing Pseudomonas putida isolate (PP36) in Brazil. The PP36 isolate was resistant to all the antimicrobials tested except polymyxin B.
Anna C S, Almeida, Marinalda A, Vilela, Felipe L S, Cavalcanti, Willames M B S, Martins, Marcos A, Morais, Marcia M C, Morais   +5 more
openaire   +2 more sources

KPC-2-producing Pseudomonas aeruginosa isolated from wild animals in Brazil. [PDF]

Braz J Microbiol, 2023
Pseudomonas aeruginosa an opportunistic pathogen that causes infections in hospitals and has high morbidity and mortality rates. In addition, it is a widely distributed environmental bacterium that can colonise a variety of habitats. Although wild animals do not have access to antibiotics, antibacterial resistance in these animals has increasingly been
Dos Santos Costa J, Dos Santos PB, de Souza ATHI, Morgado TO, Cândido SL, Silva TRD, Nakazato L, Dutra V.   +7 more
europepmc   +3 more sources

Detection of bla KPC-2 in Proteus mirabilis in Brazil [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 2015
Infections caused by Klebsiella pneumoniae carbapenemase (KPC)-producing isolates pose a major worldwide public health problem today.A carbapenem-resistant Proteus mirabilis clinical isolate was investigated for plasmid profiles and the occurrence of β-lactamase genes.The isolate exhibited resistance to ertapenem and imipenem and was susceptible to ...
Cabral, Adriane Borges, Maciel, Maria Amélia Vieira, Barros, Josineide Ferreira, Antunes, Marcelo Maranhão, Lopes, Ana Catarina Souza   +4 more
openaire   +4 more sources