Results 81 to 90 of about 32,838 (155)

Kruppel-like factor 6 regulates transforming growth factor-beta gene expression during human respiratory syncytial virus infection [PDF]

open access: yes, 2011
Background Human respiratory syncytial virus (RSV) infection is associated with airway remodeling and subsequent asthma development. Transforming growth factor-beta (TGF) plays a crucial role in asthma development.
Victoria Mgbemena   +3 more
core   +1 more source

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

open access: yesThe FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka   +3 more
wiley   +1 more source

Krüppel-like Factor 4 Inhibits Tumorigenic Progression and Metastasis in a Mouse Model of Breast Cancer

open access: yesNeoplasia: An International Journal for Oncology Research, 2011
Krüppel-like factor 4 (KLF4) is a zinc finger transcription factor that functions as an oncogene or tumor suppressor in a highly tissue-specific cell-dependent manner. However, its precise role in breast cancer and metastasis remains unclear.
Jennifer L Yori   +7 more
doaj   +1 more source

Untersuchungen zur Rolle des Transkriptionsfaktors "Krueppel-like factor 4" in der Sertoli-Zelle der Maus [PDF]

open access: yes, 2006
Der Zinkfinger-Transkriptionsfaktor "Krueppel-like factor 4" (Klf4) wird in Epithelzellen vieler Gewebe, wie z.B. des Darms, des Magens und der Haut stark exprimiert.
Godmann, Maren   +1 more
core   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin   +2 more
wiley   +1 more source

MiR-135b-5p promotes viability, proliferation, migration and invasion of gastric cancer cells by targeting Krüppel-like factor 4 (KLF4)

open access: yesArchives of Medical Science, 2019
Introduction The expression of MiR-135b-5p was up-regulated while Krüppel-like factor 4 (KLF4) expression was extremely low in human gastric carcinoma (GC) tissues.
Zhi Chen   +4 more
doaj   +1 more source

Effect of Rosuvastatin on Acute Kidney Injury in Sepsis-Associated Acute Respiratory Distress Syndrome. [PDF]

open access: yes, 2018
Background:Acute kidney injury (AKI) commonly occurs in patients with sepsis and acute respiratory distress syndrome (ARDS). Objective:To investigate whether statin treatment is protective against AKI in sepsis-associated ARDS.
Hsu, Raymond K   +5 more
core   +3 more sources

Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture

open access: yesAdvanced Genetics, Volume 7, Issue 2, June 2026.
This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley   +1 more source

Multimodal transcriptional control of pattern formation in embryonic development [PDF]

open access: yes, 2020
Predicting how interactions between transcription factors and regulatory DNA sequence dictate rates of transcription and, ultimately, drive developmental outcomes remains an open challenge in physical biology.
Galstyan, Vahe   +5 more
core   +1 more source

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