Results 121 to 130 of about 882,731 (192)

The Role of Krüppel-like Factors in Pancreatic Physiology and Pathophysiology. [PDF]

Int J Mol Sci, 2023
Giarrizzo M, LaComb JF, Bialkowska AB.
europepmc   +1 more source

Repression of cardiac hypertrophy by KLF15: underlying mechanisms and therapeutic implications.

PLoS ONE, 2012
The Kruppel-like factor (KLF) family of transcription factors regulates diverse cell biological processes including proliferation, differentiation, survival and growth. Previous studies have shown that KLF15 inhibits cardiac hypertrophy by repressing the
Joost J Leenders, Wino J Wijnen, Ingeborg van der Made, Monika Hiller, Melissa Swinnen, Thierry Vandendriessche, Marinee Chuah, Yigal M Pinto, Esther E Creemers   +8 more
doaj   +1 more source

Defining T Cell Tissue Residency in Humans: Implications for HIV Pathogenesis and Vaccine Design. [PDF]

, 2020
Purpose of review:This review summarizes recent literature defining tissue-resident memory T cells (TRM) and discusses implications for HIV pathogenesis, vaccines, and eradication efforts.Recent findings:Investigations using animal models and human ...
Ferre, April L, Kiniry, Brenna E, Shacklett, Barbara L   +2 more
core  

Direct competition between DNA binding factors highlights the role of Krüppel-like Factor 1 in the erythroid/megakaryocyte switch

Scientific Reports, 2017
The Krüppel-like factor (KLF) family of transcription factors play critical roles in haematopoiesis. KLF1, the founding member of the family, has been implicated in the control of both erythropoiesis and megakaryopoiesis.
Laura J. Norton, Samantha Hallal, Elizabeth S. Stout, Alister P. W. Funnell, Richard C. M. Pearson, Merlin Crossley, Kate G. R. Quinlan   +6 more
doaj   +1 more source

Hydroa Vacciniforme Lymphoproliferative Disorder With a Truncating KLF2 Variant Presenting as Benign Photodermatoses

Photodermatology, Photoimmunology &Photomedicine, Volume 42, Issue 3, May 2026.
John Warner‐Levy, Angelia Ong, Nina Farquharson, Jean Ayer   +3 more
wiley   +1 more source

Comprehensive Identification of the Bovine KLF Gene Family and Its Functional Regulation in Muscle Development: Insights from Single-Nuclei Transcriptomics

Animals
The Krüppel-like factor (KLF) family of transcription regulators plays pivotal roles in adipogenesis, myogenesis, and metabolism. While comprehensively studied in humans and mice, its characterization in cattle remains limited, especially within the ...
Fengying Ma, Le Zhou, Lili Guo, Chencheng Chang, Dan Dan, Yanchun Bao, Guiting Han, Mingjuan Gu, Lin Zhu, Risu Na, Caixia Shi, Jiaxin Zhang, Wenguang Zhang   +12 more
doaj   +1 more source

Clinicopathological significance of Kruppel-like factor 15 and epithelial-to-mesenchymal transition related factors in bladder cancer

Scientific Reports
The Kruppel-like factor 15(KLF15) gene functions as a crucial transcriptional modulator involved in numerous cellular processes such as differentiation, proliferation, growth, and programmed cell death.
Wenyong Li, Rudi Lv, Husong Su, Yu Fan, Wuyue Gao, Hongfei Ci, Sheng Xue   +6 more
doaj   +1 more source

ZZEF1 is a Histone Reader and Transcriptional Coregulator of Krüppel-Like Factors. [PDF]

J Mol Biol, 2021
Yu Y, Tencer A, Xuan H, Kutateladze TG, Shi X.   +4 more
europepmc   +1 more source

KLF feedback loops in innate immunity

Frontiers in Immunology
The Krüppel-like factor (KLF) family of zinc finger transcription factors regulate the expression of genes involved in a wide range of cellular processes, including cell proliferation and differentiation.
Jessica M. Salmon, Holly Adams, Graham W. Magor, Andrew C. Perkins   +3 more
doaj   +1 more source

Defective lipid metabolism associated with mutation in klf-2 and klf-3: important roles of essential dietary salts in fat storage [PDF]

, 2017
Christopher Brey, Farah Lateef, Futwan Al-Mohanna, Jun Ling, Kai Rau, Kavita Thiruchelvam, Kristopher Fernandes, Kshitij Chandel, Megan Schilling, Randy Gaugler, Ranjit Parhar, Sarwar Hashmi, Yi Wang, Zenaida P. Lopez-Dee   +13 more
core   +1 more source