Results 111 to 120 of about 882,731 (192)
Frontiers in Cell and Developmental Biology, 2019 A variety of cardiac transcription factors/cofactors, signaling pathways, and downstream structural genes integrate to form the regulatory hierarchies to ensure proper cardiogenesis in vertebrate.
Chang Xue +6 more
doaj +1 more source
Beyond the chaos: How architecture structures tumour biology
The FEBS Journal, Volume 293, Issue 9, Page 2519-2540, May 2026.Tissue architecture shapes tumour initiation and progression through multiple interconnected layers continuously remodelled over time. This review outlines how physical forces, biochemical cues, cellular niches and systemic influences contribute to tumour evolution.
Lea Dörner +3 more
wiley +1 more source
Physiological Reports, 2019 Abdominal aortic aneurysms (AAAs) are a progressive dilation of the aorta that is characterized by an initial influx of inflammatory cells followed by a pro‐inflammatory, migratory, proliferative, and eventually apoptotic smooth muscle cell phenotype. In
Morgan Salmon +4 more
doaj +1 more source
KLF7-transfected Schwann cell graft transplantation promotes sciatic nerve regeneration [PDF]
, 2017 Our former study demonstrated that Krüppel-like Factor 7 (KLF7) is a transcription factor that stimulates axonal regeneration after peripheral nerve injury.
Cheng, Yong-xia +9 more
core +1 more source
Abnormal expression of Krüppel-like transcription factors and their potential values in lung cancer
HeliyonLung cancer still is one of the most common malignancy tumors in the world. However, the mechanisms of its occurrence and development have not been fully elucidated.
Yang Shi +4 more
doaj +1 more source
The how and why of lncRNA function: An innate immune perspective. [PDF]
, 2020 Next-generation sequencing has provided a more complete picture of the composition of the human transcriptome indicating that much of the "blueprint" is a vastness of poorly understood non-protein-coding transcripts.
Carpenter, Susan +2 more
core
Transcriptional Regulation of Macrophages Polarization by MicroRNAs
Frontiers in Immunology, 2018 Diversity and plasticity are the hallmarks of cells from the monocyte–macrophage lineage. Macrophages undergo classical M1 or alternative M2 activation in response to the microenvironment signals.
Heng Li +6 more
doaj +1 more source
New insights into the anti-inflammatory mechanisms of glucocorticoids : an emerging role for glucocorticoid-receptor-mediated transactivation [PDF]
, 2013 Glucocorticoids are anti-inflammatory drugs that are widely used for the treatment of numerous (autoimmune) inflammatory diseases. They exert their actions by binding to the glucocorticoid receptor (GR), a member of the nuclear receptor family of ...
Dejager, Lien +3 more
core +1 more source
KLF4: a multifunctional nexus connecting tumor progression and immune regulation
Frontiers in ImmunologyKrüppel-like factors (KLFs) regulate various biological processes such as cell proliferation, migration, invasion, and differentiation as gene transcription factors.
Yunjie Ju +3 more
doaj +1 more source
Testicular expression of the TGF-B1 system and the control of Leydig cell proliferation [PDF]
, 2013 Transforming growth factor beta 1 (TGF-beta1) is a key regulator that modulates male reproductive function. Testicular TGF-beta1 modulates the steroidogenesis of Leydig cells, the organization of peritubular myoid cells, testis development and ...
Calandra, Ricardo Saul +2 more
core +2 more sources