ORAI1 Activates Proliferation of Lymphatic Endothelial Cells in Response to Laminar Flow Through Krüppel-Like Factors 2 and 4. [PDF]
Choi D +15 more
europepmc +2 more sources
Regulation of an inflammatory disease: Krüppel-like factors and atherosclerosis. [PDF]
Jain MK, Sangwung P, Hamik A.
europepmc +2 more sources
The Krüppel-like factors in female reproductive system pathologies. [PDF]
Simmen RC +6 more
europepmc +2 more sources
Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu +11 more
wiley +1 more source
Krüppel-like factors are effectors of nuclear receptor signaling. [PDF]
Knoedler JR, Denver RJ.
europepmc +2 more sources
Possible role of Krüppel-like factor 5 in the remodeling of small airways and pulmonary vessels in chronic obstructive pulmonary disease [PDF]
BACKGROUND: Small airway remodeling is an important cause of the airflow limitation in chronic obstructive pulmonary disease (COPD). A large population of patients with COPD also have pulmonary hypertension.
Abe, K +14 more
core +4 more sources
KLF10 integrates circadian timing and sugar signaling to coordinate hepatic metabolism
The mammalian circadian timing system and metabolism are highly interconnected, and disruption of this coupling is associated with negative health outcomes.
Anthony A Ruberto +8 more
doaj +1 more source
Krüppel-like factor 2: a central regulator of B cell differentiation and plasma cell homing
The development of B cells, their activation and terminal differentiation into antibody-producing plasma cells are characterized by alternating phases of proliferation and quiescence that are controlled by complex transcriptional networks.
Jens Wittner, Wolfgang Schuh
doaj +1 more source
Krüppel-like factor 4 transcriptionally regulates TGF-β1 and contributes to cardiac myofibroblast differentiation. [PDF]
Angiotensin II (Ang II) plays a major role in the pathogenesis of cardiac fibrosis in hypertension. It is known that Ang II induces TGF-β1 expression.
Yi Zhang +5 more
doaj +1 more source
Expression profiling of migrated and invaded breast cancer cells predicts early metastatic relapse and reveals Krüppel-like factor 9 as a potential suppressor of invasive growth in breast cancer [PDF]
Cell motility and invasion initiate metastasis. However, only a subpopulation of cancer cells within a tumor will ultimately become invasive. Due to this stochastic and transient nature, in an experimental setting, migrating and invading cells need to be
Croes, Lieselot +10 more
core +3 more sources

