Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy. [PDF]
Oncotarget, 2022 Ueno D +17 more
europepmc +1 more source
Cell Proliferation, EarlyView.Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao +7 more
wiley +1 more source
Metabolic flux from the Krebs cycle to glutamate transmission tunes a neural brake on seizure onset. [PDF]
PLoS Genet, 2021 Jeong J, Lee J, Kim JH, Lim C.
europepmc +1 more source
Inflammatory Cytokines Impair Glucagon Expression and Secretion in Pancreatic α‐Cells
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Insulin resistance and obesity‐associated inflammation are key drivers in the pathogenesis of Type 2 diabetes mellitus (T2DM). Whilst inflammatory cytokines are well known to impair β‐cell function, their impact on pancreatic α‐cells and glucagon (GCG) regulation remains poorly understood. In this study, we investigated the effects of the
Caroline Bickelmann +5 more
wiley +1 more source
STIMULATION OF THE KREBS CYCLE AND MITOCHONDRIAL BIOGENESIS THROUGH NUTRITION
This report explores the stimulation of the Krebs cycle and mitochondrial biogenesis through targeted nutrition, supplementation, and exercise. It highlights the biochemical regulation of energy metabolism and proposes integrative strategies to enhance ...
Todor Nenchev Lefterov;
core +1 more source
Combining PEGylated mito-atovaquone with MCT and Krebs cycle redox inhibitors as a potential strategy to abrogate tumor cell proliferation. [PDF]
Sci Rep, 2022 Cheng G, Hardy M, You M, Kalyanaraman B.
europepmc +1 more source
Mechanisms of Thrombocytosis in Iron‐Deficiency Anemia
European Journal of Haematology, EarlyView.ABSTRACT Iron‐deficiency anemia is frequently accompanied by reactive thrombocytosis, yet the mechanisms underlying this association remain incompletely understood. Beyond impaired erythropoiesis, iron availability has emerged as an active regulator of hematopoietic lineage decisions.
João Vitor Facco +2 more
wiley +1 more source
Krebs cycle and a mnemonic rule for memorizing the sequence of its reactions
, 2012 У лекції запропоноване мнемонічне правило для простого запам'ятовування послідовності реакцій циклу Кребса.A mnemonic rule for memorizing the sequence of Krebs cycle reactions is ...
Ефетов, К.А. +1 more
core +1 more source
From Cohesion to Norms: How Animal Groups Come, Stay, and Function Together
Ethology, EarlyView.The present review underscores two salient points: In the context of evolutionary transitions to pair‐ and group living, it is imperative to acknowledge the distinction between selective forces that act during the origin of these social systems and those that act during their subsequent maintenance.
Peter M. Kappeler
wiley +1 more source
TBDBITL Marches the Krebs Cycle
, 2004 The Ohio State Marching Band marches a pattern similar to script "O" to illustrate the Krebs Cycle.DemonstrationThe media can be accessed here: http://streaming.osu.edu/knowledgebank/TBDBITLkrebscycle.mp4Ohio State ...
Fisher, Susan
core