Results 101 to 110 of about 1,970,147 (226)

The Succinated Proteome of FH-Mutant Tumours

Metabolites, 2014
Inherited mutations in the Krebs cycle enzyme fumarate hydratase (FH) predispose to hereditary leiomyomatosis and renal cell cancer (HLRCC). Loss of FH activity in HLRCC tumours causes accumulation of the Krebs cycle intermediate fumarate to high levels,
Ming Yang, Nicola Ternette, Huizhong Su, Raliat Dabiri, Benedikt M. Kessler, Julie Adam, Bin Tean Teh, Patrick J. Pollard   +7 more
doaj   +1 more source

Changes of Microbial and Component Composition of Giraffe Milk During Mid‐ to Late Lactation

Zoo Biology, EarlyView.
Giraffe milk – graphical abstract text, Giraffe: late lactation milk, Involution at approximately 15 months of lactation, Content of saccharides and fat decrease, Protein content increases, Content of minerals increase, Microbiological quality high ABSTRACT The proximate, mineral and microbiological composition of milk from five giraffes from mid ...
G. Osthoff, C. J Hugo, S Van der Merwe, A Hugo, F Deacon   +4 more
wiley   +1 more source

Metabolic Signature of Dietary Iron Overload in a Mouse Model

Cells, 2018
Iron is an essential co-factor for several metabolic processes, including the Krebs cycle and mitochondrial oxidative phosphorylation. Therefore, maintaining an appropriate iron balance is essential to ensure sufficient energy production and to avoid ...
Chiara Volani, Giuseppe Paglia, Sigurdur V. Smarason, Peter P. Pramstaller, Egon Demetz, Christa Pfeifhofer-Obermair, Guenter Weiss   +6 more
doaj   +1 more source

Sulfate radicals enable a non-enzymatic Krebs cycle precursor

, 2020
The evolutionary origins of the tricarboxylic acid cycle (TCA), or Krebs cycle, are so far unclear. Despite a few years ago, the existence of a simple non-enzymatic Krebs-cycle catalyst has been dismissed 'as an appeal to magic', citrate and other ...
Domen Kampjut (9261443), Markus A Keller (9083573), Stuart A Harrison (9261446), Markus Ralser (46782)   +3 more
core  

Reproductive success under constraints: Does increased maternal activity during lactation offset poor habitat and individual quality in an income breeder?

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Human‐induced environmental modifications may alter forage access and, hence, how animals manage energy trade‐offs during critical periods. Reproduction, especially lactation, is the most energetically costly process for female mammals.
L. Monica Trondrud, Jean‐Michel Gaillard, Nadège C. Bonnot, Nicolas Morellet, Yannick Chaval, Arnaud Bonnet, Bruno Lourtet, A. J. Mark Hewison   +7 more
wiley   +1 more source

Changes in energetic metabolism of Biomphalaria glabrata (Mollusca, Planorbidae) in response to exogenous calcium

Brazilian Journal of Biology
Calcium is considered an essential element for the metabolism of aquatic snail Biomphalaria glabrata (Say, 1818), intermediate host of Schistosoma mansoni Sambon, 1907 in Brazil, and represents a limiting factor to its distribution and adaptation to the ...
L. D. Silva, V. C. S. Amaral, M. C. Vinaud, A. M. Castro, H. H. A. Rezende, D. B. Santos, C. C. Mello-Silva, J. C. B. Bezerra   +7 more
doaj   +1 more source

DEVS modeling and simulation of the cellular metabolism by mitochondria

, 2005
: We present a simulation model for the metabolic pathways in the cells (namely, the Glycolysis and Krebs cycle), using the DEVS formalism and the CD++ tool.
Krebs Cycle, Roxana Djafarzadeh
core  

Hotter, faster, sicker? Warming shifts the cost of infection from individuals to populations

Journal of Animal Ecology, EarlyView.
This study examines how temperature alters disease impacts across biological scales in a host–pathogen system. We found infected hosts appear healthiest at warm temperatures, yet populations suffer most. This suggests climate warming may intensify disease impacts for populations in ways traditional individual‐level virulence metrics fail to predict ...
Nathan J. Butterworth, Kerri J. Moore, Matthew D. Hall   +2 more
wiley   +1 more source

Boldness and niche width structure spatial interactions in a natural rodent community

Journal of Animal Ecology, EarlyView.
We show that individual behavioural differences (boldness) structure spatial encounter patterns within a natural multi‐species community. By linking personality to space use and interaction structure, our study demonstrates how intraspecific variation can scale up to shape community‐level processes.
Jonas Stiegler, Annika Schirmer, Jana A. Eccard, Florian Jeltsch, Melanie Dammhahn   +4 more
wiley   +1 more source

The Key Enzymes of Carbon Metabolism and the Glutathione Antioxidant System Protect Yarrowia lipolytica Yeast Against pH-Induced Stress

Journal of Fungi
In this study, we first thoroughly assayed the response of the key enzymes of energy metabolism and the antioxidant system in Yarrowia lipolytica yeast at extreme pH.
Tatyana I. Rakhmanova, Natalia N. Gessler, Elena P. Isakova, Olga I. Klein, Yulia I. Deryabina, Tatyana N. Popova   +5 more
doaj   +1 more source