Results 211 to 220 of about 51,377 (282)
ABSTRACT Marsupials lack a corpus callosum; in its place Diprodontia have a fasciculus aberrans connecting the hemispheres. However, despite this uniqueness, the realm of marsupial brain anatomy remains largely unexplored, especially through the lens of modern imaging techniques.
Natasha B. Anthoniel +4 more
wiley +1 more source
Comparison of the effect of the aerobic glycolysis inhibitor dichloroacetate and of the Krebs cycle inhibitor LW6 on cellular and humoral alloimmunity. [PDF]
Eleftheriadis T +4 more
europepmc +1 more source
Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander +5 more
wiley +1 more source
Abstract Background and Purpose Between‐cell differences in ventricular cardiomyocyte action potential duration (APD) and responses to ion channel block may contribute to pro‐arrhythmic dispersion of myocardial repolarisation. This study quantifies between‐cell physiological and pharmacological variability in the rabbit left ventricle (LV) and uses ...
Rebecca J. Gilchrist +5 more
wiley +1 more source
Developmental photoperiodic exposure (photoacclimation) from egg to adult emergence alters thermal tolerance in Ceratitis capitata. Flies reared under contrasting photoperiods (0:24, 8:16, 14:10, and 24:0 L:D) showed significant shifts in both CTmin and CTmax, whereas adult‐only photoacclimation affected CTmax but not CTmin.
Antonis G. Papadopoulos +1 more
wiley +1 more source
Free‐living birds need to acquire enough food to fulfil their energetic needs, which may require more effort in habitats with less favourable conditions. Therefore, to maintain their necessary energy intake, birds need to adjust their foraging behaviour in response to varying habitat conditions.
Renée Veenstra +5 more
wiley +1 more source
Dual Beneficial Effects of Topical l‐Glutamine on Oral Mucositis in 5‐Fluorouracil‐Treated Mice
ABSTRACT Background Oral mucositis is a severe health and economic problem that occurs in about 40%–90% of patients undergoing cancer treatments. Systemic or topical application of l‐glutamine has been shown to improve mucosal healing and ameliorate oral mucositis (OM) symptoms according to clinical score systems.
Juliana Francisca Grossi Heleno +7 more
wiley +1 more source
ABSTRACT Understanding how genetic diversity persists in populations subject to extreme demographic fluctuations and recurrent bottlenecks is a central question in evolutionary and population ecology. Cyclic species provide ideal models for investigating this ecological puzzle, as they allow testing how demographic phases shape genetic dynamics.
Julio C. Domínguez +4 more
wiley +1 more source
ABSTRACT Objectives Recent clinical studies have suggested that glucagon‐like peptide‐1 receptor (GLP‐1R) agonists may be effective therapies to treat or reduce the risk of developing secondary lymphedema. In this study, we aimed to (1) determine if GLP‐1Rs are present in the lymphatic vasculature and characterize their expression, and (2) assess the ...
Mary E. Schulz +3 more
wiley +1 more source
ABSTRACT In a scenario with increasing cases of obesity and diabetes worldwide, branched‐chain amino acids (BCAA) metabolism has become an important factor in the understanding of these pathologies. More recently, its chronic high plasma levels have been postulated, alongside glucose, inflammatory factors, and other molecules, as an important ...
Bernardo Starling‐Soares +4 more
wiley +1 more source

