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The isolated working guinea pig heart: A functional and electrophysiological characterisation
Experimental Physiology, Volume 111, Issue 7, Page 3137-3151, 1 July 2026.Abstract Small animal isolated perfused hearts have been used for over 150 years for the study of cardiac physiology and pharmacology. The guinea pig heart represents the smallest mammalian heart that replicates key features of the human heart – for example, with respect to cardiac action potential duration, ion channel expression, excitation ...
Grace C. Anderson‐Barker +1 more
wiley +1 more source
The Journal of Physiology, Volume 604, Issue 13, Page 5236-5259, 1 July 2026.Abstract figure legend AC: adenylyl cyclase, APT: adenosine triphosphate, AMP: adenosine monophosphate, cAMP: cyclic adenosine monophosphate, PDE: phosphodiesterase, PKA: protein kinase A, PPT: protein phosphatase, P: phosphorylation, RyR: ryanodine receptor, SERCA: sarcoplasmic/endoplasmic reticulum Ca2+‐adenosine triphosphatase, SR: sarcoplasmic ...
Moritz Linder +4 more
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The Journal of Physiology, Volume 604, Issue 13, Page 5200-5220, 1 July 2026.Abstract figure legend Integrated multimodal platform for panoramic cardiac mapping in isolated heart experiments. On the left, an image of the experimental setup during data acquisition showing a Langendorff‐perfused rabbit heart surrounded by three optical cameras (CAM A, B and C) positioned 120° apart, each coupled with high‐power LEDs for panoramic
Jimena Siles +8 more
wiley +1 more source
Host metabolic responses to SARS-CoV-2 and influenza viruses: parallels and contrasts. [PDF]
MetabolomicsTerra C, Terrier O, Le Gouellec A.
europepmc +1 more source
Preventive Effect of Butyrate in Colon Cancer Cell Metabolism. [PDF]
Int J Mol SciGonçalves TJ +8 more
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The Krebs Uric Acid Cycle: A Forgotten Krebs Cycle
Trends in Biochemical Sciences, 2018Hans Kornberg wrote a paper entitled 'Krebs and his trinity of cycles' commenting that every school biology student knows of the Krebs cycle, but few know that Krebs discovered two other cycles. These are (i) the ornithine cycle (urea cycle), (ii) the citric acid cycle (tricarboxylic acid or TCA cycle), and (iii) the glyoxylate cycle that was described
Jack G Salway
exaly +3 more sources
Krebs Cycle Reborn in Macrophage Immunometabolism
Annual Review of Immunology, 2020A striking change has happened in the field of immunology whereby specific metabolic processes have been shown to be a critical determinant of immune cell activation. Multiple immune receptor types rewire metabolic pathways as a key part of how they promote effector functions.
Dylan G Ryan, Luke A J O'Neill
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Genetic alterations in Krebs cycle and its impact on cancer pathogenesis
Biochimie, 2017 Cancer cells exhibit alterations in many cellular processes, including oxygen sensing and energy metabolism. Glycolysis in non-oxygen condition is the main energy production process in cancer rather than mitochondrial respiration as in benign cells ...
Farhadul Islam +2 more
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SODIUM-COUPLED TRANSPORTERS FOR KREBS CYCLE INTERMEDIATES
Annual Review of Physiology, 1999 ▪ Abstract Krebs cycle intermediates such as succinate, citrate, and α-ketoglutarate are transferred across plasma membranes of cells by secondary active transporters that couple the downhill movement of sodium to the concentrative uptake of substrate.
Ana M. Pajor
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