Results 231 to 240 of about 3,604,308 (302)

Modeling Synaptic Maturation From Growth Cone to Synapse in Human Organoids

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Synapses are implicated in several neurological disorders and psychiatric diseases. The emergence and wide use of neural organoids provide a new opportunity to study human synapses in healthy and disease settings. Therefore, we developed a simple method for the enrichment of synaptosomes and growth cone particles from forebrain organoids. The method is
Marie S. Øhlenschlæger, Lucrezia Criscuolo, Pia Jensen, Daniel J. Lloyd‐Davies Sánchez, Magdalena Sutcliffe, Santosh Bhosale, Helle Bogetofte, Muhammad Tahir, Lene A. Jakobsen, Maria Pihl, Jonathan Brewer, Veit Schwämmle, Frantz R. Poulsen, Kristine Freude, Madeline A. Lancaster, Phillip J. Robinson, Martin R. Larsen   +16 more
wiley   +1 more source

Co‐Designing a Model of Brilliant Care for Older People

Journal of Clinical Nursing, Volume 35, Issue 5, Page 2468-2482, May 2026.
ABSTRACT Aim This study aimed to co‐design a model of brilliant care for older people that provides clear, actionable principles to guide how brilliant care for older people can be realised. Background As the demand for and international importance of care for older people grows, so too does the negative discourse about care for older people.
Ann Dadich, Rachael Kearns, Ben Harris‐Roxas, Katherine Boydell, Peter Gonski, Friedbert Kohler, David Lim, Éidín Ní Shé, Carmen Amato, Imelda Gilmore, Brian Lane, Jane Mears, Frank Schaper, Rosslyn Sleeman, Elise Tcharkhedian, Varsha Tembe, Shannon Azzopardi, Kim Delbaere, Tamar Krebs, Elizabeth Paterson‐Finlay, Danielle Ni Chroinin   +20 more
wiley   +1 more source

Growth & Welfare Effects of Business Cycles In Economies with Idiosyncratic Human Capital Risk [PDF]

Tom Krebs
core  

Trophic Niche Overlap Between the Invasive Crab Rhithropanopeus harrisii (Gould, 1841) and Native Crab Species in the Southwest Atlantic Coast

Marine Ecology, Volume 47, Issue 3, May/June 2026.
ABSTRACT The introduction of exotic species is one of the main drivers of biodiversity loss in aquatic ecosystems. The Harris mud crab Rhithropanopeus harrisii, native to the Atlantic coast of North America, was recorded in the Patos Lagoon estuary (southern Brazil) in the 1980s, likely introduced via ballast water. However, the effects of this invader
Renan C. Machado, Bianca Possamai, Luiz Felipe Cestari Dumont   +2 more
wiley   +1 more source

Adipose Triglyceride Lipase and Gpr40 Contribute to the Anti‐Contractile Effect of Perivascular Adipose Tissue

Microcirculation, Volume 33, Issue 4, May 2026.
ABSTRACT Objective Perivascular adipose tissue (PVAT) surrounds most peripheral blood vessels and exerts an anti‐contractile influence through paracrine mediators. Although numerous vasoactive factors have been identified, the mechanisms linking adipocyte metabolism to PVAT‐dependent modulation of vascular tone remain poorly defined. Because adipocytes
Miranda Hyatt, Rinaldo Rodrigues Dos Passos, Fenix A. Araujo, Emily W. Wilson, Emily W. Waigi, Tiago J. Costa, Darízy F. Silva, R. Clinton Webb, Camilla F. Wenceslau, Cameron G. McCarthy   +9 more
wiley   +1 more source

Inequalities in Exclusively Mobile Interventions Targeting Weight‐Related Behaviors: Systematic Review of Observational Studies

Obesity Reviews, Volume 27, Issue 5, May 2026.
ABSTRACT Mobile health interventions are promising behavior change tools, but they might benefit deprived populations less due to disparities in intervention uptake, engagement, and effectiveness. Evidence so far mainly stems from clinical trials, which may suffer from selection bias.
Laura M. König, Cynthia C. Forbes, Heide Busse, Ann DeSmet, Dorothy Szinay, Jin Wan, Zhirui Guo, Eline S. Smit   +7 more
wiley   +1 more source

Evolutionarily Optimal Risk Aversion

Risk Analysis, Volume 46, Issue 5, May 2026.
ABSTRACT In an experimental choice situation, we identify risk‐acceptability thresholds and show how such thresholds are updated in response to benchmark information, a recurrent feature of health, safety, and environmental (HS&E) risk governance. We present a theoretical framework linking the observed behavior to an underlying evolutionary parameter ...
Chmura, Nguyen, Biermann
wiley   +1 more source

Bed rest decreases resting skeletal muscle O2 uptake and resting energy expenditure in young and elderly subjects

Experimental Physiology, Volume 111, Issue 5, Page 2599-2612, 1 May 2026.
Abstract A decrease in resting muscle O2 uptake (V̇O2m${\dot V_{{{\mathrm{O}}_2}{\mathrm{m}}}}$) described during bed rest (BR) could determine a decreased whole‐body resting energy expenditure (REE), potentially useful during prolonged spaceflights. Two groups of recreationally active men (young [Y], n = 8, age 23 ± 5 years; elderly [E], n = 10, age ...
Giovanni Baldassarre, Simone Porcelli, Lucrezia Zuccarelli, Lorenza Brocca, Noemi Arboit, Laura Gobbo, Michele Lacerenza, Alessio Marciano, Chiara Motto, Giulia Sanguin, Mladen Gasparini, Boštjan Šimunič, Rado Pišot, Marco Narici, Bruno Grassi   +14 more
wiley   +1 more source

The principles of systems biology

Experimental Physiology, Volume 111, Issue 5, Page 2438-2448, 1 May 2026.
Abstract Physiological interpretations of Systems Biology have made many advances since the Principles of Systems Biology were first published in this journal in 2008. Those advances show that the main principle, Biological Relativity, is a logical necessity since no system can exist without the form of the system.
Denis Noble, Reine Bourret
wiley   +1 more source

Pulmonary parenchyma becomes a self‐organized dissipative structure in lung cancers and pulmonary inflammatory diseases

Physiological Reports, Volume 14, Issue 9, May 2026.
Abstract Far‐from‐equilibrium thermodynamics were studied in patients with either lung cancer or pulmonary inflammatory diseases. Histological and mechanical activities were due to myofibroblasts. A study on isolated lung fragments treated with the Huxley formalism showed that mechanical abnormalities were similar in both groups: maximum velocity ...
Yves Lecarpentier, Aurélien Morini, Bruno Tremblay, Christèle Locher, Xénophon Krokidis, Victor Claes, Olivier Schussler, Christophe Locher   +7 more
wiley   +1 more source