Results 241 to 250 of about 3,153,249 (347)

The Krebs Cycle and Mitochondrial Mass Are Early Victims of Endothelial Dysfunction [PDF]

open access: bronze, 2008
Francesco Addabbo   +10 more
openalex   +1 more source

Optimal neuromuscular performance requires motor neuron phosphagen kinases

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Motor neuron (MN) terminals in fruit flies, mice and humans contain phosphagen kinases, a key enzyme in their energy storage and buffering system. Here we knocked down the primary phosphagen kinase in fruit fly larvae (arginine kinase 1 (ArgK1)) but were surprised to find that MN endurance was unaffected.
Karlis A. Justs   +10 more
wiley   +1 more source

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil   +11 more
wiley   +1 more source

Functional expression of inwardly rectifying and ATP‐sensitive potassium channels in human pulmonary artery smooth muscle and endothelial cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Inwardly rectifying (Kir2) and ATP‐sensitive (KATP) potassium channels are functionally expressed in human pulmonary artery endothelial and smooth muscle cells. The schematic illustrates how Kir2‐ and KATP‐mediated K+ efflux contributes to VM regulation and pulmonary vascular tone.
Bianca Barreira   +7 more
wiley   +1 more source

Antiplasmodial Activity and Pharmacokinetic Profiling of Cryptolepine and 2,7‐Dibromocryptolepine With a View to Informing the Design of Novel Antimalarial Cryptolepine Analogues

open access: yesDrug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT The roots of the climbing shrub Cryptolepis sanguinolenta are traditionally used in West Africa for the treatment of malaria. The principal constituent, cryptolepine (1), has been shown to have antimalarial activity but there are concerns regarding its toxicity on account of its DNA‐intercalating property.
Elodie Chenu   +7 more
wiley   +1 more source

Simultaneous investigation of cardiac pyruvate dehydrogenase flux, Krebs cycle metabolism and pH, using hyperpolarized [1,2‐13C2]pyruvate in vivo

open access: green, 2011
Albert P. Chen   +8 more
openalex   +1 more source

The Securitization Cycle: Vietnamese Migration in The Czech Republic

open access: yesInternational Migration, Volume 64, Issue 2, April 2026.
ABSTRACT This article examines how securitized governmentality shapes Czech migration policy, particularly for Vietnamese migrants. Grounded in a humanizing approach and drawing upon the Paris School securitization theory and governmentality, this research explores how security‐driven logics become embedded in institutional practices, shaping migration
Novotna Lucie   +3 more
wiley   +1 more source

Bioenergetics of protein transport into mitochondria [PDF]

open access: yes, 1988
Döhren, H. von   +4 more
core  

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