Correction to "A high-throughput TREC- and KREC-based newborn screening for severe inborn errors of immunity". [PDF]
Pediatrics Internationalsemanticscholar +2 more sources
58P Quantitative indicators of TREC and KREC excision rings in breast cancer
ESMO Open, 2023 A. Sultanbaev +8 more
semanticscholar +2 more sources
A minimal physiologically-based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti-LAG-3 monoclonal antibody. [PDF]
CPT Pharmacometrics Syst PharmacolAbstract In oncology drug development, measuring drug concentrations at the tumor site and at the targeted receptor remains an ongoing challenge. Positron emission tomography (PET)‐imaging is a promising noninvasive method to quantify intratumor exposure of a radiolabeled drug (biodistribution data) and target saturation by treatment doses in vivo ...
Michelet R +8 more
europepmc +2 more sources
UTILIZATION OF TREC AND KREC QUANTIFICATION FOR IMMUNE DEFICIENCIES RESEARCH IN MOLDOVA
Biological Markers in Fundamental and Clinical Medicine (collection of abstracts), 2019 UTILIZATION OF TREC AND KREC QUANTIFICATION FOR IMMUNE DEFICIENCIES RESEARCH IN ...
Alexandr DORIF +3 more
openalex +3 more sources
Normal neonatal TREC and KREC levels in early onset juvenile idiopathic arthritis.
Clinical Immunology, 2023 Dysregulated central tolerance predisposes to autoimmune diseases. Reduced thymic output as well as compromised central B cell tolerance checkpoints have been proposed in the pathogenesis of juvenile idiopathic arthritis (JIA). The aim of this study was to investigate neonatal levels of T-cell receptor excision circles (TRECs) and kappa-deleting ...
J. Gudmundsdottir +13 more
semanticscholar +4 more sources
Investigating the Variation of TREC/KREC in Combined Immunodeficiencies
Iranian Journal of Allergy, Asthma and Immunology, 2021 T-cell receptor excision circles (TREC)/Kappa-deleting recombination excision circles (KREC) assay has been recently recognized for detecting patients with primary (T- and/or B-cell) immunodeficiency (PID). We aimed to investigate the alterations of these biomarkers in some combined immunodeficiency patients compared to the healthy controls in ...
Leila Shakerian +11 more
openaire +3 more sources
Rapid Charge Extraction via Hole and Electron Transfer Layers on Cu<sub>2</sub>O Photocathode for Stable and Efficient Photoelectrochemical Water Reduction. [PDF]
Adv Sci (Weinh)A simple strategy is developed to construct a unique “sandwich” structure of FeOOH/Cu2O/ZnO composite photocathode. FeOOH as HTL and ZnO as ETL promote the separation of photon‐generated carriers, reduce reaction energy barrier, and enhance the HER kinetic.
Huai S +10 more
europepmc +2 more sources
Placental transfer of rituximab in extremely low birth weight infants: KREC as a tool for neonatal immune assessment. [PDF]
Pediatrics and NeonatologyTsuguma Terukina +8 more
semanticscholar +2 more sources
Swiss Medical Weekly, 2020 The recent introduction of newborn screening for severe primary T and B cell deficiencies in Switzerland allows rapid identification of patients with severe combined immunodeficiency (SCID). Outcomes for SCID are greatly improved by early diagnosis and treatment with allogeneic haematopoietic stem cell transplantation or, in selected cases, gene ...
Johannes Trück +15 more
openalex +6 more sources
Frontiers in Immunology, 2022 BackgroundLymphocyte neogenesis from primary lymphoid organs is essential for a successful reconstitution of immunity after allogeneic hematopoietic stem cell transplantation (HSCT).
Anna Söderström +11 more
doaj +1 more source