Results 21 to 30 of about 789 (158)
Screening diagnosis of primary immunodeficiencies in the practice of an allergist-immunologist
Аллергология и Иммунология в Педиатрии, 2023 .
L. Y. Barycheva +3 more
doaj +1 more source
Iranian Journal of Allergy, Asthma and Immunology, 2019 Assessment of the number of T-cell receptor excision circles (TREC) and kappa-deleting recombination excision circles (KREC) copies has been recently described as biomarkers of newly formed T and B cells respectively.
Leila Shakerian +6 more
doaj +1 more source
Features of the pre-analytical stage in quantitative determination of TREC/KREC in peripheral blood
Медицинская иммунология, 2023 The use of dried blood spots (DBS) obtained from the heels of infants has many advantages over the collection of whole blood samples. DNA extracted from DBS can be used to detect genetic diseases by PCR, which has contributed to the development of ...
M. A. Saitgalina +3 more
doaj +1 more source
Differentiating Creatine and Phosphocreatine In Vivo Using 3 T 1H MR Spectroscopy. [PDF]
Magn Reson MedABSTRACT Purpose Validation and improvements to the proton MR spectroscopic measurement of creatine and phosphocreatine in vivo at 3 T. Methods Spectral simulations were used to evaluate and explore the mitigation of LCModel fitting bias due to lineshape, signal‐to‐noise (SNR) and non‐metabolite backgrounds with a focus on phosphocreatine and the ...
Hurd RE +9 more
europepmc +2 more sources
Frontiers in Immunology, 2022 BackgroundLymphocyte neogenesis from primary lymphoid organs is essential for a successful reconstitution of immunity after allogeneic hematopoietic stem cell transplantation (HSCT).
Anna Söderström +11 more
doaj +1 more source
Assessment of trec and krec levels in COVID-19 patients with varying disease severity
Инфекция и иммунитет, 2023 According to the WHO data, the number of infected people exceeded 765.2 million people during the COVID-19 pandemic. The severity of patient’s condition is determined by immune system hyperactivation.
M. A. Saitgalina +10 more
doaj +1 more source
TREC and KREC as prognostic markers of HIV infection and COVID-19
Tuberculosis and Lung Diseases, 2022 In some infectious diseases, the number of T- and B-lymphocytes is significantly reduced which is associated with a high risk of the disease progression. The article reviews the effect of two RNA-containing viruses on the specific immune system: SARS-CoV-2 and HIV, as well as parameters of T- and B-cell neogenesis of TREC and KREC, which are markers of
E. I. Veselova +4 more
openaire +2 more sources
Newborn screening for severe combined immunodeficiency: lessons from a pilot study and prospects
Zdorovʹe Rebenka, 2023 The expansion of the neonatal screening program in Ukraine from October 2022 became an important achievement in the development of domestic medicine. Despite the severe challenges of the war and the burden of the COVID-19 pandemic, Ukraine was able to ...
O.R. Boyarchuk, N.M. Yarema, H.V. Makukh
doaj +1 more source
Lymphocyte Subgroups and KREC Numbers in Common Variable Immunodeficiency: A Single Center Study
Journal of Clinical Immunology, 2020 Common variable immunodeficiency (CVID) results in defective B cell differentiation and impaired antibody production and is the most common symptomatic primary immunodeficiency. Our aim was to evaluate the correlation among B cell subgroups, κ-deleting recombination excision circle (KREC) copy numbers, and clinical and immunological data of the ...
Ismail Yaz +9 more
openaire +4 more sources
Diagnostic value of TREC and KREC for detecting immune disorders in newborns
Allergology and Immunology in Pediatrics, 2022 .
L. Y. Barycheva +3 more
openaire +2 more sources