Results 41 to 50 of about 789 (158)

Newborn Screening Inborn Errors of Immunity in the Republic of Belarus: The First Pilot Study

Journal of Human Immunity
Background and AimsThe primary focus of neonatal screening is the early detection of asymptomatic infants with a range of serious diseases for which effective treatment is available and for which early diagnosis and intervention will prevent serious ...
E.A. Polyakova, T.P. Volodashchik, O.L. Zobikova, A.V. Liubushkin, E.A. Kalinina, S.A. Aleshkevich, Yu.S. Zharankova, I.S. Sakovich, A.N. Kupchinskaya, I.E. Guryanova, O.V. Pribushenya, S.O. Sharapova, M.V. Belevtsev, A.V. Solntsava   +13 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, Volume 600, Issue 9, Page 1265-1287, May 2026.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

DETERMINATION OF REFERENCE VALUES FOR TREC AND KREC IN DRY BLOOD SPOTS OF NEWBORNS FROM DIFFERENT GESTATION AGES IN SVERDLOVSK REGION

Медицинская иммунология, 2018
As a preparatory stage for implementation of genetic testing for severe combined immunodeficiency under a neonatal screening program, a study was performed in Sverdlovsk Region which concerned quantitative determination of T and B cell neogenesis markers
S. S. Deryabina, I. A. Tuzankina, V. N. Shershnev   +2 more
doaj   +1 more source

Comparative analysis of reagent kits for DNA extraction from dry blood stains

Медицинская иммунология, 2023
Neonatal screening is a mandatory newborn screening procedure that detects the presence of genetic diseases. Dry blood stains are used for mass screening of children.
A. V. Sedykh, M. A. Saitgalina, Yu. V. Ostankova, A. A. Totolian   +3 more
doaj   +1 more source

THE ROLE OF TREC AND KREC IN ASSESSING THE IMMUNE STATUS OF NEWBORNS

Eurasian Journal of Applied Biotechnology
Newborn screening, based on the quantitative assessment of T-cell receptor excision circles (TREC) and kappa-deleting recombination excision circles (KREC) in dried blood spots, allows for the early diagnosis of various types of primary immunodeficiencies.
N. Sikhayeva, S. Volodchenko, E. Kovzel, M. Kissykova, M. Morenko, K. Shnaider, G. Tortayeva, Ye. Sagandykova   +7 more
openaire   +1 more source

Sacrificial Leaching Enables Fe‐Rich Oxyhydroxide Reconstruction on In2S3 Photoanode

Interdisciplinary Materials, Volume 5, Issue 3, Page 477-486, May 2026.
Photoelectrochemical activation of a NiFe oxyhydroxide layer on an In2S3 photoanode triggers selective sacrificial Ni leaching and surface porosification. This dynamic process induces interfacial reconstruction, generating an intimately coupled, amorphous Fe‐rich catalytic overlayer.
Zhenhao He, Tianyun Liu, Dongniu Wang, Yulong Huang, Linxing Meng, Liang Li   +5 more
wiley   +1 more source

Clinical and Genetic Study of X-linked Agammaglobulinemia Patients (The Benefit of Early Diagnosis)

Iranian Journal of Allergy, Asthma and Immunology, 2020
X-linked agammaglobulinemia (XLA) is a primary immunodeficiency caused by genetic defects in the Bruton tyrosine kinase (Btk) gene. XLA is characterized as an antibody deficiency by recurrent bacterial infections, the absence of peripheral B cells, and ...
Zahra Alizadeh, Parisa Dashti, Marzieh Mazinani, Maryam Nourizadeh, Leila Shakerian, Shaghayegh Tajik, Masoud Movahedi, Setareh Mamishi, Zahra Pourpak, Mohammad Reza Fazlollahi   +9 more
doaj   +1 more source

Repairing Errors With Elaborative Feedback in Computerised Learning Environments

Journal of Computer Assisted Learning, Volume 42, Issue 2, April 2026.
ABSTRACT Background Although automatic elaborative feedback (EF) is effective for teaching conceptual learning in science, there is insufficient evidence on how to adapt it in computer‐based question‐answering activities. Objectives This study aims to examine how we can make automatic EF more effective and tailored according to the knowledge revision ...
Tomás Martínez, Arantxa García, Raquel Cerdán, Eduardo Vidal‐Abarca   +3 more
wiley   +1 more source

Levels of T-cell Receptor Excision Circles and B-cell κ-deletion Element in Patients with Stages I–III Ovarian Cancer

Креативная хирургия и онкология
Introduction. Ovarian cancer is the ninth most common malignant neoplasm. This condition often causes severe complications, such as loss of reproductive organs, which is particularly characteristic of hereditary forms of the cancer.
Alexander V. Sultanbaev, Irina A. Tuzankina, Konstantin V. Menshikov, Ainur F. Nasretdinov, Shamil I. Musin, Alfiia A. Fatikhova, Nadezhda I. Sultanbaeva, Adel A. Izmailov, Mikhail V. Sultanbaev, Dmitry A. Kudlay   +9 more
doaj   +1 more source

Immunodeficiency Disorders in Congenital Heart Diseases (Review)

Педиатрическая фармакология, 2023
The study data of the last two decades on primary and secondary immunodeficiency in congenital heart defects (CHD) as a cause of frequent infectious complications before and after cardiac surgery are presented. Based on screenings of various levels, data
Elena A. Degtyareva, Bupe M. Mwela, Andrey P. Prodeus, Dmitry Yu. Ovsyannikov, Marina G. Kantemirova, Olga V. Alekseeva, Dmitry A. Kudlay, Alexey I. Kim, Inessa E. Nefedova, Tatiana V. Rogova, Margarita R. Tumanyan, Ilya A. Korsunskiy   +11 more
doaj   +1 more source