Gene regulatory factors of the sea urchin embryo. II. Two dissimilar proteins, P3A1 and P3A2, bind to the same target sites that are required for early territorial gene expression [PDF]
Previous work demonstrated that a negative regulatory interaction mediated by factor(s) termed 'P3A' is required for correct territory-specific gene expression in the sea urchin embryo. A probe derived from a P3A target site in the skeletogenic SM50 gene
Britten, Roy J.+4 more
core
Ischemia–reperfusion injury (IRI) is a predominant factor leading to delayed graft function (DGF) following kidney transplantation. MicroRNAs (miRNAs) play a pivotal role in the pathogenesis of renal IRI, with ferroptosis being a critical driving force ...
Haitao Yu, Xin Gou
doaj +1 more source
Most Probable Evolution Trajectories in a Genetic Regulatory System Excited by Stable Lévy Noise [PDF]
We study the most probable trajectories of the concentration evolution for the transcription factor activator in a genetic regulation system, with non-Gaussian stable L\'evy noise in the synthesis reaction rate taking into account. We calculate the most probable trajectory by spatially maximizing the probability density of the system path, i.e., the ...
arxiv
Human Kruppel-like Factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription [PDF]
Jane van Vliet+2 more
openalex +1 more source
The Kruppel-like KLF4 Transcription Factor, a Novel Regulator of Urokinase Receptor Expression, Drives Synthesis of This Binding Site in Colonic Crypt Luminal Surface Epithelial Cells [PDF]
Heng Wang+3 more
openalex +1 more source
We recently demonstrated the generation of mouse induced tissue-specific stem (iTS) cells through transient overexpression of reprogramming factors combined with tissue-specific selection. Here we induced expandable tissue-specific progenitor (iTP) cells
Hirofumi Noguchi+8 more
doaj
Regulation of endothelial cell activity and vascular inflammation by shear stress [PDF]
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
3rd Micro and Nano Flows Conference (MNF2011)+1 more
core
Krüppel-like transcription factors and control of pluripotency. [PDF]
Bourillot PY, Savatier P.
europepmc +1 more source
Hypoxia Triggers SENP1 (Sentrin-Specific Protease 1) Modulation of KLF15 (Kruppel-Like Factor 15) and Transcriptional Regulation of Arg2 (Arginase 2) in Pulmonary Endothelium [PDF]
Deepesh Pandey+10 more
openalex +1 more source
Many efforts have been made to reveal the mechanisms underlying skeletal muscle development because of its importance in animals. However, knowledge on chromatin accessibility, a prerequisite for gene expression, remains limited. Here, dynamic changes in
Dongjie Zhang+6 more
doaj +1 more source