Results 201 to 210 of about 33,501 (214)

Induction of cancer stem cells from mouse fibroblasts. [PDF]

open access: yesSci Rep
Shabrish S   +13 more
europepmc   +1 more source

Kruppel-like Transcription Factor-10 (KLF10) suppresses the TGF beta-induced epithelial-to-mesenchymal transition

open access: yes, 2018
Mishra, Vivek Kumar   +8 more
openaire   +1 more source

The Kruppel-like zinc finger transcription factor, GLI-similar 1, is regulated by hypoxia-inducible factors via non-canonical mechanisms.

open access: yesThe Kruppel-like zinc finger transcription factor, GLI-similar 1, is regulated by hypoxia-inducible factors via non-canonical mechanisms.
openaire  

Kruppel-like factor 2 Transcriptional Regulation Involves Heterogeneous Nuclear Ribonucleoproteins and Acetyltransferases

Biochemistry, 2005
Kruppel-like factor 2 (KLF2) is expressed in several cell types, and knockout animals have shown that KLF2 gene regulation is involved in multiple biological processes. These include maintaining T-cells in the quiescent state, preventing preadipocytes from differentiating into mature adipocytes, stabilizing blood vessel walls through endothelial cell ...
Nisar, Ahmad, Jerry B, Lingrel
openaire   +2 more sources

Transcription factor Kruppel-like factor 5 positively regulates the expression of AarF domain containing kinase 4

Molecular Biology Reports, 2020
AarF domain containing kinase 4 (ADCK4) is identified as a candidate gene associated with hereditary nephrotic syndrome (NS). Kruppel-like factor 5 (KLF5) is reported to promote podocyte survival by blocking the ERK/p38 MAPK pathways. Both ADCK4 and KLF5 are involved in the occurrence and development of podocyte disease, but their interaction remains ...
Xi Chen   +4 more
openaire   +2 more sources

Transcriptional regulation of ion channel gene expression by Kruppel-like factors (KLFs)

2022
Balanced expression of ion channels in neurons is critical for maintaining healthy brain activity. Mutations in ion channel genes leading to neuropsychiatric diseases have been extensively studied.
openaire   +1 more source

Kruppel-like factor 9 inhibits growth and metastasis of cholangiocarcinoma cells by targeted regulation of metallothionein 1 M transcription

Tissue and Cell, 2022
This study is to investigate the effect of Kruppel-like factor 9 (KLF9) on the occurrence and progression of cholangiocarcinoma (CCA) and its underlying mechanism. After the CCA cells were transfected with OE-KLF9 and/or sh-metallothionein 1 M (sh-MT1M), KLF9 and MT1M expression levels were measured.
Lin, Zhou   +5 more
openaire   +2 more sources

Kruppel‐Like Factor 15: A Critical Transcriptional Regulator Of Hypoxia Induced Endothelial Arginase 2

The FASEB Journal, 2016
Objective Kruppel Like Factor 15 has recently been shown to be critical for activation of proinflammatory processes in vascular smooth muscle and atherogenesis. Although KLF15 is abundantly expressed in vascular endothelium there is a significant lack of knowledge regarding the role of KLF15 in the regulation of
Deepesh Pandey   +4 more
openaire   +1 more source

Kruppel-like transcription factor 5 promotes breast cell survival through pERK-mediated MKP-1 protein stabilization.

Cancer Research, 2009
Abstract Abstract #3019 Kruppel-like Factor 5 (KLF5) is a transcription factor promoting cell survival and tumorigenesis in multiple cancers. High level of KLF5 mRNA is associated with a shorter survival for breast cancer patients. However, the role of KLF5 and mechanism of KLF5 actions in breast cancer remain unclear.
R Liu, Z Zhou, C Chen
openaire   +1 more source

Abstract 344: Kruppel-like Factor 15: A Critical Transcriptional Regulator of Hypoxia Induced Endothelial Arginase 2

Arteriosclerosis, Thrombosis, and Vascular Biology, 2016
Objective: Kruppel Like Factor 15 has recently been shown to be critical for activation of proinflammatory processes in vascular smooth muscle and atherogenesis. Although KLF15 is abundantly expressed in vascular endothelium there is a significant lack of knowledge regarding the role of KLF15 in the regulation of vascular ...
Deepesh Pandey, Dan Berkowitz, Lew Romer
openaire   +1 more source

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