Results 61 to 70 of about 193,609 (276)

A novel zinc finger transcriptional repressor, ZNF224, interacts with the negative regulatory element (AldA-NRE) and inhibits gene expression [PDF]

, 2003
The interaction between the negative cis-element (AldA-NRE) and p97 repressor nuclear protein is a key step in modulating transcription of the human and mouse aldolase A (AldA) gene during the cell cycle and differentiation.
Agata, Coqueret, Costanzo, Costanzo, Dignam, Izzo, Kadonaga, Klug, Lupo, Lupo, Lupo, Margolin, Palm, Philipsen, Postigo, Salminen, Schultz, Stauffer, Turner, Witzgall   +19 more
core   +1 more source

Krüppel-like factor 6 regulates transforming growth factor-β gene expression during human respiratory syncytial virus infection

Virology Journal, 2011
Background Human respiratory syncytial virus (RSV) infection is associated with airway remodeling and subsequent asthma development. Transforming growth factor-beta (TGF) plays a crucial role in asthma development.
Chang TeHung, Segovia Jesus, Mgbemena Victoria, Bose Santanu   +3 more
doaj   +1 more source

Acquisition of cancer stem cell properties in osteosarcoma cells by defined factors

Stem Cell Research & Therapy, 2020
Background Cancer stem cells (CSCs) are considered to be responsible for tumor initiation, formation, and poor prognosis of cancer patients. However, the rarity of CSCs in clinical samples makes it difficult to elucidate characteristics of CSCs ...
Shuichi Fujiwara, Teruya Kawamoto, Yohei Kawakami, Yasufumi Koterazawa, Hitomi Hara, Toshiyuki Takemori, Kazumichi Kitayama, Shunsuke Yahiro, Kenichiro Kakutani, Tomoyuki Matsumoto, Takehiko Matsushita, Takahiro Niikura, Michiyo Koyanagi-Aoi, Takashi Aoi, Ryosuke Kuroda, Toshihiro Akisue   +15 more
doaj   +1 more source

Coding limits on the number of transcription factors [PDF]

BMC Genomics 2006, 7:239, 2010
Transcription factor proteins bind specific DNA sequences to control the expression of genes. They contain DNA binding domains which belong to several super-families, each with a specific mechanism of DNA binding. The total number of transcription factors encoded in a genome increases with the number of genes in the genome. Here, we examined the number
arxiv   +1 more source

A systems biology analysis of brain microvascular endothelial cell lipotoxicity. [PDF]

, 2014
BackgroundNeurovascular inflammation is associated with a number of neurological diseases including vascular dementia and Alzheimer's disease, which are increasingly important causes of morbidity and mortality around the world.
Aung, Hnin H, Rutledge, John C, Tagkopoulos, Ilias, Tsoukalas, Athanasios   +3 more
core   +2 more sources

Branched-Chain Amino Acid Negatively Regulates KLF15 Expression via PI3K-AKT Pathway. [PDF]

, 2017
Recent studies have linked branched-chain amino acid (BCAA) with numerous metabolic diseases. However, the molecular basis of BCAA's roles in metabolic regulation remains to be established.
Dong, Weibing, Liu, Yunxia, Shao, Jing, Sun, Haipeng, Wang, Yibin, Zhou, Meiyi   +5 more
core   +2 more sources

Klf4, Klf2, and Zfp148 activate autophagy‐related genes in smooth muscle cells during aortic aneurysm formation

Physiological Reports, 2019
Abdominal aortic aneurysms (AAAs) are a progressive dilation of the aorta that is characterized by an initial influx of inflammatory cells followed by a pro‐inflammatory, migratory, proliferative, and eventually apoptotic smooth muscle cell phenotype. In
Morgan Salmon, Michael Spinosa, Zendra E. Zehner, Gilbert R. Upchurch, Gorav Ailawadi   +4 more
doaj   +1 more source

Kruppel‐like transcription factor KLF8 regulates of early adipocyte differentiation

The FASEB Journal, 2012
KLF8 is a zinc‐finger transcription factor known to play an essential role in cell cycle and differentiation. However, its physiological roles and functions in 3T3‐L1 cells remain relatively unclear. In the present study, we showed that KLF8 acts as a key regulator controlling adipocyte differentiation.
Jung Hwan Yu, Yoo Jeong Lee, Hyo Jung Kim, Jae Woo Kim, Hyeonjin Choi, Hyemin Lee   +5 more
openaire   +1 more source

Krüppel-Like Transcription Factor 13 Regulates T Lymphocyte Survival In Vivo [PDF]

The Journal of Immunology, 2007
Abstract Krüppel-like transcription factor (KLF)13, previously shown to regulate RANTES expression in vitro, is a member of the Krüppel- like family of transcription factors that controls many growth and developmental processes. To ascertain the function of KLF13 in vivo, Klf13-deficient mice were generated by gene targeting.
Lu Zhou, Lisa A. McPherson, Yong Tae Ahn, Shu-Chen Lyu, Demin Wang, Carol Clayberger, Chen Dong, Dongdong Feng, Xiaoyan Shi, An Song, Alan M. Krensky, Meixia Zhou   +11 more
openaire   +3 more sources

Evasion of anti-growth signaling: a key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds [PDF]

, 2015
The evasion of anti-growth signaling is an important characteristic of cancer cells. In order to continue to proliferate, cancer cells must somehow uncouple themselves from the many signals that exist to slow down cell growth.
A.R.M. Ruhul Amin, Abraham, Adorno, Ahmad, Akhurst, Alan Bilsland, Albertoni, Alexandros G. Georgakilas, Amedeo Amedei, Amin, Amin, Amin, Amr Amin, Apelqvist, Arbiser, Aronchik, Asfar S. Azmi, Aster, Athar, Baek, Baek, Baek, Baek, Bagli, Bahr, Balasubramanyam, Banerjee, Barry, Bateman, Bauskin, Bean, Beckerman, Belletti, Berletch, Bhattacharyya, Bian, Bill Helferich, Bock, Bolos, Bolos, Bootcov, Bracken, Bray, Bray, Breen, Brooks, Brown, Brown, Brown, Buck, Bunney, Cancer Genome Atlas Research, Cantero, Cekanova, Chandra S. Boosani, Charles, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Cheng, Chintharlapalli, Choi, Choudhuri, Christofori, Classon, Clem, Cordero-Espinoza, Cornen, Costa, Covey, Cui, Dai, Dai, Dallas, Damera, Dameron, Daniels, Dardousis, Debeb, Decristofaro, Dell’Eva, Deng, Denissova, Dennis, Dhar, Di, Dickinson, Dickson, Ding, Dipita Bhakta, Dominguez, Dong, Dong M. Shin, Dorota Halicka, Dotsch, Douc-Rasy, Du, Dudas, Durfort, D’Angelo, Ehebauer, Elena Niccolai, Enderle, Engelman, Evans, Fang, Fang, Farabegoli, Faridoni-Laurens, Fernandez, Firth, Fischbach, Fotsis, Fox, Freed-Pastor, Friday, Fuggetta, Gabellini, Gao, Garcia, Garofalo, Gazala N. Khan, Giovannini, Gloria S. Huang, Goldstein, Griner, Grogan, Gualberto, Guan, Guan, Gudkov, Guha, Gui, Gullett, Guo, Guo, Guo, Guo, Gupta, Haddad, Hahm, Hahm, Hahn, Hald, Hanahan, Hardcastle, Hardtner, Harper, Hartog, Harvey, Hastak, Hayes, Heallen, Hebert, Hendrickson, Hennessy, Herman-Antosiewicz, Heyninck, Heyninck, Hiromasa Fujii, Ho-Young Lee, Hoffmann, Hollander, Holy, Hossain, Huang, Huang, Huang, Hudson, Humbel, Husaini, Hussain, Hwa, Ichimiya, Indovina, Ishida, Jack Arbiser, Jacque, Jang, Jerome, Ji, Jia, Jiang, Jin-Tang Dong, Joerg Reichrath, Jogie-Brahim, Johnson, Jones, Joshi, Jung, Kahlert, Kan, Kang, Kanya Honoki, Karpowicz, Katagiri, Katia Aquilano, Kaushik, Kennedy, Khan, Khaw, Khaw, Kim, Kim, Kim, Kim, Kim, Kim, Kim, King, Knudsen, Knuutila, Koduru, Kohno, Kong, Konishi, Kooijman, Koopmann, Koopmann, Kopelovich, Kovalev, Kunnumakkara, Kurosu, Kwak, Lai, Lam, Lamar, Lambert, Lamonte, Lanzilli, Leao, Lee, Lee, Lee, LeRoith, Leupin, Levine, Li, Li, Li, Li, Li, Li, Liang, Lichner, Licitra, Lin, Lin, Lin, Lindmark, Liu, Liu, Liu, Liu-Chittenden, Loukopoulos, Lundberg, Luo, Luo, Ma, Maher, Maillard, Majumdar, Malaguarnera, Mamo, Mankame, Maor, Maria Rosa Ciriolo, Martinez, Martinez-Garcia, Massi, Maxwell, McClatchey, McGrath, Medema, Mendivil, Menendez, Miele, Mimeault, Min, Mitra, Miyake, Miyamoto, Mizuno, Mohan, Moll, Moon, Moore, Morgillo, Murga, Murillo, Murtaugh, Nagl, Nahta, Nair, Nakamura, Nallet-Staub, Nandakumar, Nandan, Nandan, Nandan, Nasiri, National Cancer Genome Atlas Research, Nefedova, Negi, Ng, Nian, Nihal, Ogawara, Oh, Oh, Okuyama, Omer Kucuk, Ono, Osada, Ouchi, Overholtzer, Pal, Pankov, Park, Park, Peacock, Phillip A. Karpowicz, Pinnix, Pollak, Pollak, Ponnurangam, Pons, Pratheeshkumar, Premkumar, Rao, Reed, Reedijk, Reedijk, Reidy, Reinmuth, Reisman, Ren, Riedemann, Rita Nahta, Rizzo, Rogler, Rosenfeldt, Roy, Rufini, Ryan, S. Salman Ashraf, Sadava, Samani, Santer, Santoro, Sarkar, Sasiela, Sausen, Schlegelmilch, Schmidt, Selander, Senapati, Serrano, Shamim, Shammas, Shangary, Shankar, Shankar, Sharif, Sharma, Shi, Shih Ie, Shijun Mi, Shim, Shim, Shimizu, Shin, Shindo, Shnaper, Shrimali, Siddiqui, Singh, Sinha, Sjolund, Somaira Nowsheen, Sophie Chen, Sotoca, Staal, Staff, Stockhausen, Stoeltzing, Stupack, Su, Subbaramaiah, Suh, Sulma I. Mohammed, Sun, Sunahara, Sur, Szarc vel Szic, Tan, Tan, Tannapfel, Tao, Thaiparambil, Thamilselvan, Thomas E. Carey, Tian, Ting, Trimboli, Tsui, Ulanet, Ulbricht, Valenti, van der Veeken, Vanhara, Varelas, Varelas, Villanueva, Volate, Vousden, W. Nicol Keith, Wallace, Wallin, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Weinberg, Welsh, Wen, Weng, Werner, Werner, Wesolowska, Wetterau, Whitson, Wiegand, Wiklund, William, Wilson, Wolf, Wong, Wu, Wu, Wu, Wynne, Xie, Xing, Xu, Xue, Xujuan Yang, Yamaguchi, Yamamoto, Yan, Yang, Yang, Yang, Yasaei, Yavari, Yee, Yin, Ying, Yokomizo, Yokomizo, Yonekura, Youns, Yu, Yu, Yu, Yu, Zaika, Zang, Zanotto-Filho, Zender, Zgheib, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zhao, Zhao, Zheng, Zheng, Zhong, Zhu, Zhuo G. Chen, Zilfou, Zlotogorski   +515 more
core   +1 more source