Results 1 to 10 of about 24,542 (261)

Metabolic reprogramming and metabolic sensors in KSHV-induced cancers and KSHV infection [PDF]

open access: yesCell & Bioscience, 2021
Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic gammaherpesvirus associated with several human cancers. KSHV infection and KSHV-induced anabolic cell proliferation and cellular transformation depend on reprogramming of cellular metabolic ...
Tingting Li, Shou-Jiang Gao
doaj   +3 more sources

Towards Understanding KSHV Fusion and Entry [PDF]

open access: yesViruses, 2019
How viruses enter cells is of critical importance to pathogenesis in the host and for treatment strategies. Over the last several years, the herpesvirus field has made numerous and thoroughly fascinating discoveries about the entry of alpha-, beta-, and ...
Stephen J. Dollery
doaj   +3 more sources

Suppression of DC-SIGN and gH Reveals Complex, Subset-Specific Mechanisms for KSHV Entry in Primary B Lymphocytes

open access: yesViruses, 2021
Kaposi sarcoma-associated herpesvirus (KSHV) is the causative agent of multiple cancers in immunocompromised patients including two lymphoproliferative disorders associated with KSHV infection of B lymphocytes.
Nancy Palmerin   +5 more
doaj   +1 more source

Investigation of CDH1 germline mutations in Turkish patients with Kaposi’s sarcoma

open access: yesTürk Biyokimya Dergisi, 2022
Kaposi’s sarcoma (KS) develops from the lining cells of blood or lymphatic vessels and may appear as red, purple, brown, or black lesions. E-cadherin, CDH1, is a cell adhesion molecule located on the surface of epithelial cells.
Celik Betul, Tuncer Seref Bugra
doaj   +1 more source

The Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) gH/gL Complex Is the Predominant Neutralizing Antigenic Determinant in KSHV-Infected Individuals

open access: yesViruses, 2020
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the etiological agent of Kaposi’s sarcoma (KS), one of the most prevalent cancers of people living with HIV/AIDS in sub-Saharan Africa.
Yasaman Mortazavi   +5 more
doaj   +1 more source

Non-human primate model of Kaposi's sarcoma-associated herpesvirus infection. [PDF]

open access: yesPLoS Pathogens, 2009
Since Kaposi's sarcoma-associated herpesvirus (KSHV or human herpesvirus 8) was first identified in Kaposi's sarcoma (KS) lesions of HIV-infected individuals with AIDS, the basic biological understanding of KSHV has progressed remarkably.
Heesoon Chang   +8 more
doaj   +1 more source

Update on Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) – review

open access: yesRomanian Journal of Internal Medicine, 2020
Human herpesvirus 8 (HHV8), also known as Kaposi sarcoma-associated herpesvirus (KSHV), is one of the few pathogens recognized as direct carcinogen, being involved in the pathogenesis of Kaposi sarcoma, primary effusion lymphoma and multicentric ...
Iftode Nicoleta   +3 more
doaj   +1 more source

Virally encoded interleukin-6 facilitates KSHV replication in monocytes and induction of dysfunctional macrophages.

open access: yesPLoS Pathogens, 2023
Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic double-stranded DNA virus and the etiologic agent of Kaposi's sarcoma and hyperinflammatory lymphoproliferative disorders.
Michiko Shimoda   +6 more
doaj   +1 more source

The ubiquitin/proteasome system mediates entry and endosomal trafficking of Kaposi's sarcoma-associated herpesvirus in endothelial cells. [PDF]

open access: yesPLoS Pathogens, 2012
Ubiquitination, a post-translational modification, mediates diverse cellular functions including endocytic transport of molecules. Kaposi's sarcoma-associated herpesvirus (KSHV), an enveloped herpesvirus, enters endothelial cells primarily through ...
Whitney Greene   +5 more
doaj   +1 more source

Association between malaria exposure and Kaposi's sarcoma-associated herpes virus seropositivity in Uganda. [PDF]

open access: yes, 2015
OBJECTIVE: Unlike other herpes viruses, Kaposi's sarcoma-associated herpes virus (KSHV) is not ubiquitous worldwide and is most prevalent in sub-Saharan Africa. The reasons for this are unclear. As part of a wider investigation of factors that facilitate
Cose, Stephen   +8 more
core   +2 more sources

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