Results 1 to 10 of about 12,453 (165)

Metabolic reprogramming and metabolic sensors in KSHV-induced cancers and KSHV infection [PDF]

open access: yesCell & Bioscience, 2021
Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic gammaherpesvirus associated with several human cancers. KSHV infection and KSHV-induced anabolic cell proliferation and cellular transformation depend on reprogramming of cellular metabolic ...
Tingting Li, Shou-Jiang Gao
doaj   +3 more sources

Cross‐Species Insights Into Gamma Herpesvirus Transcriptomes: Long‐Read and Multi‐Omics Perspectives [PDF]

open access: yesJournal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Comparative transcriptome analyses of gamma herpesviruses have been revolutionized by long‐read sequencing and integrative multi‐omics approaches, enabling unprecedented resolution of viral gene expression. Cross‐species studies of Kaposi's sarcoma‐associated herpesvirus (KSHV), Epstein–Barr virus (EBV), and murine gamma herpesvirus 68 (MHV68)
Ritu Shekhar   +4 more
wiley   +2 more sources

Suppression of DC-SIGN and gH Reveals Complex, Subset-Specific Mechanisms for KSHV Entry in Primary B Lymphocytes

open access: yesViruses, 2021
Kaposi sarcoma-associated herpesvirus (KSHV) is the causative agent of multiple cancers in immunocompromised patients including two lymphoproliferative disorders associated with KSHV infection of B lymphocytes.
Nancy Palmerin   +5 more
doaj   +1 more source

Investigation of CDH1 germline mutations in Turkish patients with Kaposi’s sarcoma

open access: yesTürk Biyokimya Dergisi, 2022
Kaposi’s sarcoma (KS) develops from the lining cells of blood or lymphatic vessels and may appear as red, purple, brown, or black lesions. E-cadherin, CDH1, is a cell adhesion molecule located on the surface of epithelial cells.
Celik Betul, Tuncer Seref Bugra
doaj   +1 more source

The Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) gH/gL Complex Is the Predominant Neutralizing Antigenic Determinant in KSHV-Infected Individuals

open access: yesViruses, 2020
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the etiological agent of Kaposi’s sarcoma (KS), one of the most prevalent cancers of people living with HIV/AIDS in sub-Saharan Africa.
Yasaman Mortazavi   +5 more
doaj   +1 more source

Non-human primate model of Kaposi's sarcoma-associated herpesvirus infection. [PDF]

open access: yesPLoS Pathogens, 2009
Since Kaposi's sarcoma-associated herpesvirus (KSHV or human herpesvirus 8) was first identified in Kaposi's sarcoma (KS) lesions of HIV-infected individuals with AIDS, the basic biological understanding of KSHV has progressed remarkably.
Heesoon Chang   +8 more
doaj   +1 more source

Update on Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) – review

open access: yesRomanian Journal of Internal Medicine, 2020
Human herpesvirus 8 (HHV8), also known as Kaposi sarcoma-associated herpesvirus (KSHV), is one of the few pathogens recognized as direct carcinogen, being involved in the pathogenesis of Kaposi sarcoma, primary effusion lymphoma and multicentric ...
Iftode Nicoleta   +3 more
doaj   +1 more source

Virally encoded interleukin-6 facilitates KSHV replication in monocytes and induction of dysfunctional macrophages.

open access: yesPLoS Pathogens, 2023
Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic double-stranded DNA virus and the etiologic agent of Kaposi's sarcoma and hyperinflammatory lymphoproliferative disorders.
Michiko Shimoda   +6 more
doaj   +1 more source

Establishment of Tree Shrew Animal Model for Kaposi’s Sarcoma-Associated Herpesvirus (HHV-8) Infection

open access: yesFrontiers in Microbiology, 2021
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the most common cause of Kaposi’s sarcoma (KS) and other malignant growths in humans. However, the lack of a KSHV-infected small animal model has hampered understanding of the mechanisms of KSHV infection,
Daoqun Li   +9 more
doaj   +1 more source

The ubiquitin/proteasome system mediates entry and endosomal trafficking of Kaposi's sarcoma-associated herpesvirus in endothelial cells. [PDF]

open access: yesPLoS Pathogens, 2012
Ubiquitination, a post-translational modification, mediates diverse cellular functions including endocytic transport of molecules. Kaposi's sarcoma-associated herpesvirus (KSHV), an enveloped herpesvirus, enters endothelial cells primarily through ...
Whitney Greene   +5 more
doaj   +1 more source

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