Results 91 to 100 of about 24,542 (261)

METTL16 controls Kaposi’s sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle

Cell Death and Disease, 2023
Oncogenic Kaposi’s sarcoma-associated herpesvirus (KSHV) consists of latent and lytic replication phases, both of which are important for the development of KSHV-related cancers.
Xinquan Zhang, Wen Meng, Jian Feng, Xinghong Gao, Chao Qin, Pinghui Feng, Yufei Huang, Shou-Jiang Gao   +7 more
doaj   +1 more source

Raman tweezers provide the fingerprint of cells supporting the late stages of KSHV reactivation [PDF]

, 2009
Kaposi's sarcoma-associated herpesvirus (KSHV) has both latent and lytic phases of replication. The molecular switch that triggers a reactivation is still unclear. Cells from S phase of cell cycle provide apt conditions for an active reactivation.
Akula, Akula, Akula, Blasig, Borchman, Bryan, Cesarman, Chan, Chandriani, Chang, Cook, Dadarlat, De Chen, Dezube, Diamond, Duca, Dyson, Ensoli, Ford, Ganem, Glaser, Glaunsinger, Gross, Grundhoff, Hamden, Hamden, Hinz, Jenner, Jess, Jordan, Krek, Lambert, Lukas, Mao, McAllister, Medema, Medveczky, Meng, Notingher, Ohrvik, Ossie F. Dyson, Patrick W. Ford, Platt, Ramser, Raso, Renne, Seiler, Shaw, Shaw M. Akula, Staskus, Sun, Uzunbajakava, Wang, Whitby, Whitman, Xie, Yong-Qing Li   +56 more
core   +1 more source

Mapping protein–protein interactions by mass spectrometry

Mass Spectrometry Reviews, Volume 45, Issue 1, Page 69-106, January/February 2026.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M. Cristea, Markku Varjosalo   +4 more
wiley   +1 more source

KSHV microRNAs: Tricks of the Devil [PDF]

Trends in Microbiology, 2017
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma (KS), a vascular tumor frequently found in immunodeficient individuals. KSHV encodes 12 pre-microRNAs (pre-miRNAs), which are processed into 25 mature microRNAs (miRNAs).
Jie, Qin, Wan, Li, Shou-Jiang, Gao, Chun, Lu   +3 more
openaire   +2 more sources

Selective autophagy impedes KSHV entry after recruiting the membrane damage sensor galectin-8 to virus-containing endosomes

Cell Reports
Summary: Kaposi sarcoma-associated herpesvirus (KSHV) is an oncogenic γ-herpesvirus. Autophagy during KSHV entry has remained unexplored. We show that LC3 lipidation as a hallmark of autophagy is induced shortly after KSHV entry.
Katarina Wendy Schmidt, Charlotte Montespan, Danielle Thompson, Miriam S. Lucas, Laure-Anne Ligeon, Harald Wodrich, Alexander S. Hahn, Urs F. Greber, Christian Münz   +8 more
doaj   +1 more source

Genipin Enhances Kaposi's Sarcoma-Associated Herpesvirus Genome Maintenance. [PDF]

PLoS ONE, 2016
Kaposi's sarcoma-associated herpesvirus (KSHV) is a Gammaherpesvirus that causes acute infection and establishes life-long latency. KSHV causes several human cancers, including Kaposi's sarcoma, an acquired immune deficiency syndrome (AIDS)-related form ...
Miyeon Cho, Seok Won Jung, Soomin Lee, Kuwon Son, Gyu Hwan Park, Jong-Wha Jung, Yu Su Shin, Taegun Seo, Hyosun Cho, Hyojeung Kang   +9 more
doaj   +1 more source

Viral hijacking of cellular metabolism. [PDF]

, 2019
This review discusses the current state of the viral metabolism field and gaps in knowledge that will be important for future studies to investigate.
Ch'ng, James, Christofk, Heather R, Thaker, Shivani K   +2 more
core  

Multiple human herpesvirus-8 infection [PDF]

, 2003
In Malawian patients with Kaposi sarcoma (KS) and their relatives, we investigated nucleotide-sequence variation in human herpesvirus-8 (HHV-8) subgenomic DNA, amplified from oral and blood samples by use of polymerase chain reaction.
Beyari, MM, Cook, RD, Hodgson, TA, Kondowe, W, Molyneux, EM, Porter, SR, Scully, CM, Teo, CG   +7 more
core   +1 more source

Supplementary Figure 2 from A Purine Scaffold HSP90 Inhibitor BIIB021 Has Selective Activity against KSHV-Associated Primary Effusion Lymphoma and Blocks vFLIP K13-Induced NF-κB [PDF]

, 2023
Gopalakrishnan Ramakrishnan, Hittu Matta, Preet M. Chaudhary   +2 more
openalex   +1 more source

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source