Results 101 to 110 of about 24,542 (261)

KSHV-Mediated Angiogenesis in Tumor Progression [PDF]

Viruses, 2016
Human herpesvirus 8 (HHV-8), also known as Kaposi’s sarcoma-associated herpesvirus (KSHV), is a malignant human oncovirus belonging to the gamma herpesvirus family. HHV-8 is closely linked to the pathogenesis of Kaposi’s sarcoma (KS) and two other B-cell lymphoproliferative diseases: primary effusion lymphoma (PEL) and a plasmablastic variant of ...
Pravinkumar Purushothaman, Timsy Uppal, Roni Sarkar, Subhash Verma   +3 more
openaire   +4 more sources

Kaposi’s Sarcoma-Associated Herpesvirus-Encoded circRNAs Are Expressed in Infected Tumor Tissues and Are Incorporated into Virions

mBio, 2020
Kaposi’s sarcoma-associated herpesvirus (KSHV) has recently been found to generate circular RNAs (circRNAs) from several KSHV genes, most abundantly from K10 (viral interferon regulatory factor 4 [vIRF4]), K7.3, and polyadenylated nuclear (PAN) RNA.
Bizunesh Abere, Jinghui Li, Hongzhao Zhou, Tuna Toptan, Patrick S. Moore, Yuan Chang   +5 more
doaj   +1 more source

Constitutive activation of T cells by γ2-herpesviral GPCR through the interaction with cellular CXCR4 [PDF]

, 2017
Members of the herpesviral family use multiple strategies to hijack infected host cells and exploit cellular signaling for their pathogenesis and latent infection.
Aigerim, A, Cha, J.S, Cho, H.-S, Cho, N.-H., Choi, M.-S, Han, S.K, Kim, H, Kim, K, Kim, S, Kim, Y, Kwon, E.-K, Lee, J.-W, Min, C.-K, Nam, H.-J, Schmidt, S   +14 more
core   +1 more source

Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy

The FEBS Journal, Volume 293, Issue 2, Page 325-347, January 2026.
The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro, Martina Bergant Marušič, Justyna Broniarczyk   +2 more
wiley   +1 more source

Prevalence of Kaposi’s sarcoma-associated herpesvirus in Uygur and Han populations from the Urumqi and Kashgar regions of Xinjiang, China [PDF]

, 2017
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the infectious etiologic agent associated with Kaposi’s sarcoma (KS), primary effusion lymphoma, and multicentric Castleman disease.
Cui, Meng, Han, Li-Li, Liu, Zhen-Qiu, Shu, Zhan-Jun, Wood, Charles, Yang, Yang, Zeng, Yan, Zhang, Tiejun, Zheng, Jun   +8 more
core   +1 more source

Nucleolar Localization of HIV-1 Rev Is Required, Yet Insufficient for Production of Infectious Viral Particles. [PDF]

, 2018
Combination antiretroviral therapy fails in complete suppression of HIV-1 due to drug resistance and persistent latency. Novel therapeutic intervention requires knowledge of intracellular pathways responsible for viral replication, specifically those ...
Arizala, Jerlisa Ann C, Burnett, John C, Li, Haitang, Ouellet, Dominique L, Rossi, John J, Takahashi, Mayumi   +5 more
core   +1 more source

Molecular Biology of KSHV Lytic Reactivation [PDF]

Viruses, 2015
Kaposi’s sarcoma-associated herpesvirus (KSHV) primarily persists as a latent episome in infected cells. During latent infection, only a limited number of viral genes are expressed that help to maintain the viral episome and prevent lytic reactivation. The latent KSHV genome persists as a highly ordered chromatin structure with bivalent chromatin marks
Pravinkumar Purushothaman, Timsy Uppal, Subhash Verma   +2 more
openaire   +4 more sources

Heterogeneity and breadth of host antibody response to KSHV infection demonstrated by systematic analysis of the KSHV proteome.

PLoS Pathogens, 2014
The Kaposi sarcoma associated herpesvirus (KSHV) genome encodes more than 85 open reading frames (ORFs). Serological evaluation of KSHV infection now generally relies on reactivity to just one latent and/or one lytic protein (commonly ORF73 and K8.1 ...
Nazzarena Labo, Wendell Miley, Vickie Marshall, William Gillette, Dominic Esposito, Matthew Bess, Alexandra Turano, Thomas Uldrick, Mark N Polizzotto, Kathleen M Wyvill, Rachel Bagni, Robert Yarchoan, Denise Whitby   +12 more
doaj   +1 more source

Inhibition of a viral enzyme by a small-molecule dimer disruptor. [PDF]

, 2009
We identified small-molecule dimer disruptors that inhibit an essential dimeric protease of human Kaposi's sarcoma-associated herpesvirus (KSHV) by screening an alpha-helical mimetic library.
Arnold, Leggy A, Craik, Charles S, Guy, R Kiplin, Lazic, Ana, Lee, Gregory M, Roels, Christina M, Shahian, Tina, Velusamy, Priya   +7 more
core  

Study of variable stars in the MOA data base: long-period red variables in the Large Magellanic Cloud [PDF]

, 2001
One hundred and forty six long-period red variable stars in the Large Magellanic Cloud (LMC) from the three year MOA project database were analysed. A careful periodic analysis was performed on these stars and a catalogue of their magnitudes, colours ...
Alard, Alcaino, Barthes, Becker, Bedding, C. Noguchi, Caputo, D.J. Sullivan, F. Abe, Feast, Feast, Feast, Feast, G.R. Nankivell, Glass, Glass, H. Sato, Hearnshaw, Holtzman, Hughes, I.A. Bond, J. Jugaku, J. Skuljan, J.B. Hearnshaw, K. Masuda, K. Ohnishi, Kato, Kienzle, Kurochkin, Leavitt, M. Honda, M. Honma, M. Reid, M. Sekiguchi, M. Takeuti, M. Yoshizawa, N.J. Rattenbury, Noda, P.C.M. Yock, P.M. Kilmartin, R. Yamada, R.J. Dodd, S. Kabe, S. Noda, S. Wilkinson, Schechter, Smak, Stellingwerf, T. Nakamura, T. Sumi, T. Yanagisawa, Takeuti, To. Saito, Trams, Walker, Whitelock, Whitelock, Whitelock, Wood, Wood, Y. Kan-ya, Y. Kato, Y. Matsubara, Y. Muraki, Y. Watase, Yanagisawa   +65 more
core   +2 more sources