Results 11 to 20 of about 16,928 (247)
KSHV: Immune Modulation and Immunotherapy [PDF]
Frontiers in Immunology, 2020 Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) is associated with KS, primary effusion lymphoma (PEL), and multicentric Castleman disease (MCD).
Grant S Broussard, B. Damania
semanticscholar +5 more sources
Regulation of KSHV Latency and Lytic Reactivation [PDF]
Viruses, 2020 Kaposi’s sarcoma-associated herpesvirus (KSHV) is associated with three malignancies— Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD). Central to the pathogenesis of these diseases is the KSHV viral life
Grant S Broussard, B. Damania
semanticscholar +4 more sources
KSHV Genome Replication and Maintenance [PDF]
Frontiers in Microbiology, 2016 Kaposi's sarcoma associated herpesvirus (KSHV) or human herpesvirus 8 (HHV8) is a major etiological agent for multiple severe malignancies in immune-compromised patients.
Pravinkumar Purushothaman +4 more
semanticscholar +6 more sources
KSHV and Kaposi's Sarcoma: The End of the Beginning? [PDF]
Cell, 1997 Don Ganem
openalex +4 more sources
Kaposi Sarcoma-Associated Herpesvirus Sequencing in People Living With HIV in the Southern United States Reveals Subtype Diversity and Multiple Infections. [PDF]
J Med VirolABSTRACT Kaposi sarcoma‐associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma and lymphoproliferative diseases collectively identified as KSHV‐associated diseases (KAD). While KAD incidence has decreased across the United States, regional and population‐based variability exists, with higher rates in southern states. To understand the
Marshall VA +13 more
europepmc +2 more sources
The Role of Bacteria in KSHV Infection and KSHV-Induced Cancers [PDF]
Cancers, 2021 The objective of this article is to review the current status of the bacteria-virus interplay in Kaposi’s sarcoma-associated herpesvirus (KSHV) infection and KSHV-driven cancers. KSHV is the etiological agent of several cancers, including Kaposi’s sarcoma (KS) and primary effusion lymphoma.
Markazi, Ashley +4 more
openaire +5 more sources
KSHV vIL6 Inhibits Functional B Cell Maturation During De Novo Infection. [PDF]
J Med VirolABSTRACT Despite causative links to lymphoproliferative disorders, little is known about early events governing KSHV infection in B lymphocytes. IL‐6 signaling plays a critical role in KSHV‐mediated disease, with human IL‐6 (hIL6) levels correlating with viral load and disease progression.
Zakir W, Osborn JM, Totonchy JE.
europepmc +2 more sources
Viral Enhancers Orchestrate Kaposi's Sarcoma-Associated Herpesvirus Transcription. [PDF]
J Med VirolABSTRACT Kaposi's sarcoma‐associated herpesvirus (KSHV), the etiological agent of Kaposi's sarcoma and other lymphoproliferative disorders, presents a delicate balance between host cell manipulation, and orchestrating its transcriptional repertoire.
Chowdhury NR, Shamay M.
europepmc +2 more sources
Structure and Antigenicity of Kaposi's Sarcoma-Associated Herpesvirus Glycoprotein B. [PDF]
Adv Sci (Weinh)Kaposi's sarcoma‐associated herpesvirus (KSHV) causes severe cancers without effective treatments. This study presents an atomic model of KSHV's critical infection protein, gB, revealing a unique structure shared with related herpesviruses like Epstein‐Barr virus (EBV). The structural similarity highlights vulnerable targets for antibodies, guiding the
Fang XY +8 more
europepmc +2 more sources
PLoS Pathogens, 2021 Liquid-liquid phase separation (LLPS) can drive formation of diverse and essential macromolecular structures, including those specified by viruses. Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) genomes associate with the viral encoded Latency-Associated
O. Vladimirova +5 more
semanticscholar +1 more source