Results 21 to 30 of about 22,488 (214)

Twenty Years of KSHV [PDF]

open access: yesViruses, 2014
Twenty years ago, Kaposi’s sarcoma (KS) was the oncologic counterpart to Winston Churchill’s Russia: a riddle, wrapped in a mystery, inside an enigma. First described by Moritz Kaposi in 1872, who reported it to be an aggressive skin tumor, KS became known over the next century as a slow-growing tumor of elderly men—in fact, most KS patients were ...
Chang, Y, Moore, P
openaire   +3 more sources

Latently KSHV-Infected Cells Promote Further Establishment of Latency upon Superinfection with KSHV [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Kaposi’s sarcoma-associated herpesvirus (KSHV) is a cancer-related virus which engages in two forms of infection: latent and lytic. Latent infection allows the virus to establish long-term persistent infection, whereas the lytic cycle is needed for the maintenance of the viral reservoir and for virus spread.
Chen Gam ze Letova   +3 more
openaire   +2 more sources

Establishment of Tree Shrew Animal Model for Kaposi’s Sarcoma-Associated Herpesvirus (HHV-8) Infection

open access: yesFrontiers in Microbiology, 2021
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the most common cause of Kaposi’s sarcoma (KS) and other malignant growths in humans. However, the lack of a KSHV-infected small animal model has hampered understanding of the mechanisms of KSHV infection,
Daoqun Li   +9 more
doaj   +1 more source

Association between malaria exposure and Kaposi's sarcoma-associated herpes virus seropositivity in Uganda. [PDF]

open access: yes, 2015
OBJECTIVE: Unlike other herpes viruses, Kaposi's sarcoma-associated herpes virus (KSHV) is not ubiquitous worldwide and is most prevalent in sub-Saharan Africa. The reasons for this are unclear. As part of a wider investigation of factors that facilitate
Cose, Stephen   +8 more
core   +2 more sources

High-throughput sequencing analysis of a "hit and run" cell and animal model of KSHV tumorigenesis.

open access: yesPLoS Pathogens, 2020
Kaposi's sarcoma (KS), is an AIDS-associated neoplasm caused by the KS herpesvirus (KSHV/ HHV-8). KSHV-induced sarcomagenesis is the consequence of oncogenic viral gene expression as well as host genetic and epigenetic alterations. Although KSHV is found
Julian Naipauer   +7 more
doaj   +1 more source

Reactive oxygen species hydrogen peroxide mediates Kaposi's sarcoma-associated herpesvirus reactivation from latency. [PDF]

open access: yesPLoS Pathogens, 2011
Kaposi's sarcoma-associated herpesvirus (KSHV) establishes a latent infection in the host following an acute infection. Reactivation from latency contributes to the development of KSHV-induced malignancies, which include Kaposi's sarcoma (KS), the most ...
Fengchun Ye   +7 more
doaj   +1 more source

IL-21 signaling promotes the establishment of KSHV infection in human tonsil lymphocytes by increasing differentiation and targeting of plasma cells

open access: yesFrontiers in Immunology, 2022
IntroductionFactors influencing Kaposi’s sarcoma-associated herpesvirus (KSHV) transmission and the early stages of KSHV infection in the human immune system remain poorly characterized.
Nedaa Alomari, Jennifer Totonchy
doaj   +1 more source

The zebrafish xenograft platform-A novel tool for modeling KSHV-associated diseases [PDF]

open access: yes, 2019
Kaposi\u27s sarcoma associated-herpesvirus (KSHV, also known as human herpesvirus-8) is a gammaherpesvirus that establishes life-long infection in human B lymphocytes.
Berman, Jason N   +12 more
core   +2 more sources

KSHV: forgotten but not gone [PDF]

open access: yesBlood, 2011
Thirty years ago, Kaposi sarcoma (KS) arose as a prominent manifestation of the AIDS epidemic. Seventeen years ago we discovered the virus that causes KS,1 Kaposi sarcoma–associated herpesvirus (KSHV), and within a year KSHV had been also shown to be the likely cause of AIDS-associated primary effusion lymphoma (PEL)2 and most cases of multicentric ...
Patrick S, Moore, Yuan, Chang
openaire   +2 more sources

Prevalence of Kaposi's sarcoma-associated herpesvirus and transfusion-transmissible infections in Tanzanian blood donors

open access: yesInternational Journal of Infectious Diseases, 2020
Objective: Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent for Kaposi's sarcoma (KS), one of the most common cancers in Tanzania. We have investigated KSHV prevalence and factors associated with KSHV infection in Tanzania.
Salum J. Lidenge   +7 more
doaj   +1 more source

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