Results 31 to 40 of about 24,542 (261)

The zebrafish xenograft platform-A novel tool for modeling KSHV-associated diseases [PDF]

, 2019
Kaposi\u27s sarcoma associated-herpesvirus (KSHV, also known as human herpesvirus-8) is a gammaherpesvirus that establishes life-long infection in human B lymphocytes.
Berman, Jason N, Coombs, Andrew J, Dellaire, Graham, Druley, Todd E, Ha, Michael N, McCormick, Craig, Melong, Nicole, O\u27Leary, David, Pringle, Eric S, Robinson, Carolyn-Ann, Veinotte, Chansey, Wertman, Jaime, Young, Andrew L   +12 more
core   +2 more sources

KSHV: forgotten but not gone [PDF]

Blood, 2011
Thirty years ago, Kaposi sarcoma (KS) arose as a prominent manifestation of the AIDS epidemic. Seventeen years ago we discovered the virus that causes KS,1 Kaposi sarcoma–associated herpesvirus (KSHV), and within a year KSHV had been also shown to be the likely cause of AIDS-associated primary effusion lymphoma (PEL)2 and most cases of multicentric ...
Patrick S, Moore, Yuan, Chang
openaire   +2 more sources

IL-21 signaling promotes the establishment of KSHV infection in human tonsil lymphocytes by increasing differentiation and targeting of plasma cells

Frontiers in Immunology, 2022
IntroductionFactors influencing Kaposi’s sarcoma-associated herpesvirus (KSHV) transmission and the early stages of KSHV infection in the human immune system remain poorly characterized.
Nedaa Alomari, Jennifer Totonchy
doaj   +1 more source

Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation [PDF]

, 2013
Kaposi's sarcoma-associated herpesvirus (KSHV) has been linked to the development of Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease (MCD). We have characterized the role of KSHV-encoded viral FLICE inhibitory protein K13
Ahmad, B. Tolani, Ballon, Benhamou, Bower, Bren, C. Graham, Chang, Chaudhary, Chugh, Delmore, Dong, Du, Dupin, Dupin, Eeva, Eeva, Field, Gerondakis, Guasparri, H. Matta, H. Yi, Hassman, Herzog, Lee, Liu, Madureira, Matta, Matta, Matta, Matta, Mineva, Nador, Niiro, P. M. Chaudhary, Parravicini, Punj, Schauer, Soulier, Sun, Sun, Sun, Thome, Vrzalikova, Waterston, Wu, Wu, Wu, Y. Suo, Y. Yang, Yang, Yang, Young, Zhao   +53 more
core   +1 more source

A Kaposi’s sarcoma-associated herpes virus-encoded microRNA contributes to dilated cardiomyopathy

Signal Transduction and Targeted Therapy, 2023
Dilated cardiomyopathy (DCM) is the leading cause of heart transplantation. By microRNA (miRNA) array, a Kaposi’s sarcoma-associated herpes virus (KSHV)-encoded miRNA, kshv-miR-K12-1-5p, was detected in patients with DCM.
Yanru Zhao, Huaping Li, Hengzhi Du, Zhongwei Yin, Mengying He, Jiahui Fan, Xiang Nie, Yang Sun, Huiying Hou, Beibei Dai, Xudong Zhang, Yuanyuan Cai, Kunying Jin, Nan Ding, Zheng Wen, Jiang Chang, Chen Chen, Dao Wen Wang   +17 more
doaj   +1 more source

The activation of KSHV lytic cycle blocks autophagy in PEL cells [PDF]

, 2015
This study confirms that autophagy is activated concomitantly with KSHV lytic cycle induction, and that autophagy inhibition by BECN1 knockdown reduces viral lytic gene expression.
CIRONE, Mara, FAGGIONI, Alberto, FARINA, Antonella, Filardi, M, GONNELLA, ROBERTA, GRANATO, Marisa, SANTARELLI, Roberta, TORRISI, Maria Rosaria   +7 more
core   +1 more source

Dimethyl Sulfoxide Enhances Kaposi’s Sarcoma-Associated Herpesvirus Production During Lytic Replication

Frontiers in Microbiology, 2021
Kaposi’s sarcoma-associated herpesvirus (KSHV) is an etiologic agent of Kaposi’s sarcoma, primary effusion lymphoma, and multicentric Castleman disease. In studies of KSHV, efficient virus production and isolation are essential.
Su-Kyung Kang, Myung-Ju Lee, Ho-Hyun Ryu, Jisu Lee, Myung-Shin Lee, Myung-Shin Lee   +5 more
doaj   +1 more source

Short communication: NKG2C+ NK cells contribute to increases in CD16+CD56- cells in HIV type 1+ individuals with high plasma viral load. [PDF]

, 2012
Chronic HIV-1 infection results in the expansion of both NKG2C+ and CD16+CD56- human natural killer cells. NKG2C+ cells proliferate in response to human cytomegalovirus (HCMV) and expansion of the dysfunctional CD56-CD16+ natural killer (NK) cells is ...
Bower, Mark, Gazzard, Brian G, Goodier, Martin R, Gregson, John NS, Kuri-Cervantes, Leticia, Mela, Christopher M   +5 more
core   +1 more source

Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future [PDF]

, 2015
Constitutively activated prosurvival pathways render cancer cells addicted to their effects. Consequently they turn out to be the Achilles’ heels whose inhibition can be exploited in anticancer therapy.
CIRONE, Mara, FAGGIONI, Alberto, FARINA, Antonella, GONNELLA, ROBERTA, GRANATO, Marisa, SANTARELLI, Roberta, TRIVEDI, PANKAJ   +6 more
core   +4 more sources

Kaposi’s Sarcoma-Associated Herpesvirus and Host Interaction by the Complement System

Pathogens, 2020
Kaposi’s sarcoma-associated herpesvirus (KSHV) modulates the immune response to allow the virus to establish persistent infection in the host and facilitate the development of KSHV-associated cancer.
Seung-Min Yoo, Myung-Shin Lee
doaj   +1 more source