Results 41 to 50 of about 16,928 (247)

High-throughput sequencing analysis of a "hit and run" cell and animal model of KSHV tumorigenesis.

open access: yesPLoS Pathogens, 2020
Kaposi's sarcoma (KS), is an AIDS-associated neoplasm caused by the KS herpesvirus (KSHV/ HHV-8). KSHV-induced sarcomagenesis is the consequence of oncogenic viral gene expression as well as host genetic and epigenetic alterations. Although KSHV is found
Julian Naipauer   +7 more
doaj   +1 more source

A Kaposi’s sarcoma-associated herpes virus-encoded microRNA contributes to dilated cardiomyopathy

open access: yesSignal Transduction and Targeted Therapy, 2023
Dilated cardiomyopathy (DCM) is the leading cause of heart transplantation. By microRNA (miRNA) array, a Kaposi’s sarcoma-associated herpes virus (KSHV)-encoded miRNA, kshv-miR-K12-1-5p, was detected in patients with DCM.
Yanru Zhao   +17 more
doaj   +1 more source

IL-21 signaling promotes the establishment of KSHV infection in human tonsil lymphocytes by increasing differentiation and targeting of plasma cells

open access: yesFrontiers in Immunology, 2022
IntroductionFactors influencing Kaposi’s sarcoma-associated herpesvirus (KSHV) transmission and the early stages of KSHV infection in the human immune system remain poorly characterized.
Nedaa Alomari, Jennifer Totonchy
doaj   +1 more source

Cell death inhibition by KSHV [PDF]

open access: yesAging, 2015
Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of the endothelial cell-derived tumor Kaposi's sarcoma and of the lymphoproliferative disorders primary effusion lymphoma and multicentric Castleman's disease. The life cycle of KSHV includes a latent and a lytic/productive phase that both contribute to tumorigenic activity.
Christoph Becker   +2 more
openaire   +2 more sources

KSHV infection skews macrophage polarisation towards M2-like/TAM and activates Ire1 α-XBP1 axis up-regulating pro-tumorigenic cytokine release and PD-L1 expression

open access: yesBritish Journal of Cancer, 2020
Background Kaposi’s Sarcoma Herpesvirus (KSHV) is a gammaherpesvirus strongly linked to human cancer. The virus is also able to induce immune suppression, effect that contributes to onset/progression of the viral-associated malignancies.
M. S. Gilardini Montani   +9 more
semanticscholar   +1 more source

KSHV [PDF]

open access: yes, 2014
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8) is the etiologic agent of Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. These cancers often occur in the context of immunosuppression, which has made KSHV-associated malignancies an increasing global health concern with the persistence
Louise Giffin, Blossom Damania
openaire   +3 more sources

Analysis of the Expression Pattern of microRNA of KSHV in KSHV-infected Human Cells [PDF]

open access: yesJournal of Bacteriology and Virology, 2013
Kaposi"s sarcoma associated herpesvirus (KSHV) is subdivided into gamma-herpesvirus and causes Kaposi"s sarcoma in human immunodeficiency virus (HIV)-infected patients. A defining feature of herpesviral biology is the presence of two alternative genetic lifestyles - a latent infection and a lytic replicative cycle.
Jaehyuk Jang   +3 more
openaire   +2 more sources

Human Herpesvirus 8 in Solid Organ Transplant Donors and Recipients: Need for Screening? A Dutch Seroprevalence Pilot Study. [PDF]

open access: yesJ Med Virol
Abstract Human Herpesvirus 8 (HHV8) also called Kaposi's Sarcoma‐associated herpesvirus (KSHV) is endemic worldwide. It is particularly pathogenic in immunocompromised patients. HHV8 related disease is a rare but dreaded complication in Solid Organ Transplant (SOT) recipients.
Roo-Brand G   +3 more
europepmc   +2 more sources

Dimethyl Sulfoxide Enhances Kaposi’s Sarcoma-Associated Herpesvirus Production During Lytic Replication

open access: yesFrontiers in Microbiology, 2021
Kaposi’s sarcoma-associated herpesvirus (KSHV) is an etiologic agent of Kaposi’s sarcoma, primary effusion lymphoma, and multicentric Castleman disease. In studies of KSHV, efficient virus production and isolation are essential.
Su-Kyung Kang   +5 more
doaj   +1 more source

Selected genes of Human herpesvirus-8 associated Kaposi's sarcoma among patients with Human Immunodeficiency Virus-1 and Acquired Immunodeficiency Disease Syndrome

open access: yesThe Pan African Medical Journal, 2019
INTRODUCTION: Kaposi's sarcoma (KS) is a kind of cancer that causes flat or raised lesions containing Human herpes virus 8 (HHV8). The KS lesions are common among immunosuppressed HIV patients.
Rodgers Norman Demba   +3 more
doaj   +1 more source

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