Results 41 to 50 of about 22,488 (214)
Multicyclic D‐Stereospecific Hydrolase Dimer With High Sustained Activity
Angewandte Chemie, EarlyView.Protein macrocyclization was applied to a thermally unstable D‐stereospecific hydrolase using in situ cyclization of proteins (INCYPRO). This site‐specific cross‐linking approach enhanced the resistance of the enzyme to heat and cosolvents.
Anissa Haim +10 more
wiley +2 more sources
The Pan African Medical Journal, 2019 INTRODUCTION: Kaposi's sarcoma (KS) is a kind of cancer that causes flat or raised lesions containing Human herpes virus 8 (HHV8). The KS lesions are common among immunosuppressed HIV patients.
Rodgers Norman Demba +3 more
doaj +1 more source
Infectious Agents and Cancer, 2011 Background Kaposi sarcoma (KS) is the most common AIDS-defining tumour in HIV-infected individuals in Africa. Kaposi sarcoma herpes virus (KSHV) infection precedes development of KS.
Maskew Mhairi +5 more
doaj +1 more source
Kaposi’s Sarcoma-Associated Herpesvirus and Host Interaction by the Complement System
Pathogens, 2020 Kaposi’s sarcoma-associated herpesvirus (KSHV) modulates the immune response to allow the virus to establish persistent infection in the host and facilitate the development of KSHV-associated cancer.
Seung-Min Yoo, Myung-Shin Lee
doaj +1 more source
PLoS Pathogens, 2017 Kaposi sarcoma-associated herpesvirus (KSHV) causes several tumors and hyperproliferative disorders. Hypoxia and hypoxia-inducible factors (HIFs) activate latent and lytic KSHV genes, and several KSHV proteins increase the cellular levels of HIF.
Coralie Viollet +7 more
doaj +1 more source
Metabolic reprogramming of Kaposi's sarcoma associated herpes virus infected B-cells in hypoxia. [PDF]
PLoS Pathogens, 2018 Kaposi's sarcoma associated herpesvirus (KSHV) infection stabilizes hypoxia inducible factors (HIFs). The interaction between KSHV encoded factors and HIFs plays a critical role in KSHV latency, reactivation and associated disease phenotypes.
Rajnish Kumar Singh +4 more
doaj +1 more source
Quantitative Analysis of Kaposi Sarcoma–Associated Herpesvirus (KSHV) in KSHV‐Associated Diseases [PDF]
The Journal of Infectious Diseases, 2006 Accurate numbers of copies of Kaposi sarcoma-associated herpesvirus (KSHV) and numbers of virus-infected cells in lesions caused by KSHV-associated diseases are unknown.Quantitative polymerase chain reaction (PCR) and computerized imaging of immunohistochemical analysis were performed on pathologic sections of samples from persons with KSHV-associated ...
Yasuko, Asahi-Ozaki +4 more
openaire +2 more sources
Frontiers in Microbiology, 2012 Soon after the discovery of Kaposi sarcoma (KS)-associated herpesvirus (KSHV), it was appreciated that this virus was associated with most cases of multicentric Castleman disease (MCD) arising in patients infected with human immunodeficiency virus.
Mark N. Polizzotto +3 more
doaj +1 more source
Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy [PDF]
, 2017 KSHV and EBV are gammaherpesviruses strictly linked to human cancers. Even if the majority of cancer cells harbor a latent infection, the few cells that undergo viral replication may contribute to the pathogenesis and maintenance of the virus-associated ...
Cirone, Mara +7 more
core +2 more sources
BMC Infectious Diseases, 2023 Background This study aimed to facilitate the understanding of the transmission route and risk factors that might contribute to the infection of Kaposi’s sarcoma associated herpesvirus (KSHV) among men who have sex with men (MSM).
Yi Li +5 more
doaj +1 more source