Results 61 to 70 of about 16,928 (247)

Prevalence and correlates of Kaposi’s sarcoma-associated herpesvirus and herpes simplex virus type 2 infections among adults: evidence from the NHANES III data

Virology Journal, 2022
Background Kaposi’s sarcoma-associated herpes virus (KSHV) prevalence and risk factors exhibit considerable variations across populations in different geographic regions. Determinants and the transmission routes of KSHV infection are uncertain.
Xin Zhang, Yiyun Xu, Yi Li, Huangbo Yuan, Zhenqiu Liu, Tiejun Zhang   +5 more
doaj   +1 more source

The Prevalence of EBV and KSHV in Odontogenic Lesions

International Dental Journal, 2023
Odontogenic lesions evolve as a result of altered dental development. This study aimed to evaluate the prevalence and the coinfection of Epstein-Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus (KSHV) in radicular cysts, dentigerous cysts, odontogenic keratocysts, and ameloblastomas.Polymerase chain reaction (PCR) was used to analyse 66 cases
Mohammed Amjed Alsaegh, Okba Mahmoud, Sudhir Rama Varma, Shengrong Zhu   +3 more
openaire   +3 more sources

Seroprevalence and risk factors for Kaposi’s Sarcoma associated herpesvirus among men who have sex with men in Shanghai, China

BMC Infectious Diseases, 2023
Background This study aimed to facilitate the understanding of the transmission route and risk factors that might contribute to the infection of Kaposi’s sarcoma associated herpesvirus (KSHV) among men who have sex with men (MSM).
Yi Li, Xingcan Zhang, Yue Zhang, Minqi Wei, Sijie Tao, Ying Yang   +5 more
doaj   +1 more source

Kaposi’s sarcoma-associated herpesvirus infection promotes proliferation of SH-SY5Y cells by the Notch signaling pathway

Cancer Cell International, 2021
Background The cancer caused by Kaposi’s sarcoma-associated herpesvirus (KSHV) infection is one of the major causes of death in AIDS patients. Some patients have neurological symptoms, which appear to be associated with KSHV infection, based on the ...
Dongdong Cao, Shuyuan Wu, Xiaolu Wang, Ying Li, Huiling Xu, Zemin Pan, Zhaofu Wu, Lei Yang, Xiaohua Tan, Dongmei Li   +9 more
doaj   +1 more source

KSHV activates unfolded protein response sensors but suppresses downstream transcriptional responses to support lytic replication

PLoS Pathogens, 2019
Herpesviruses usurp host cell protein synthesis machinery to convert viral mRNAs into proteins, and the endoplasmic reticulum (ER) to ensure proper folding, post-translational modification and trafficking of secreted and transmembrane viral proteins ...
Benjamin P. Johnston, Eric S. Pringle, C. McCormick   +2 more
semanticscholar   +1 more source

miRNAs and their roles in KSHV pathogenesis

Virus Research, 2019
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiological agent of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman Disease (MCD). Recent mechanistic advances have discerned the importance of microRNAs in the virus-host relationship. KSHV has two modes of replication: lytic and latent phase.
Hosni A. M. Hussein, Pranaya Pakala, James A. McCubrey, Mohammad A. Alfhili, Shaw M. Akula, Sandra Simon, Jaffer Hussain   +6 more
openaire   +3 more sources

Oncogenic KSHV-encoded interferon regulatory factor upregulates HMGB2 and CMPK1 expression to promote cell invasion by disrupting a complex lncRNA-OIP5-AS1/miR-218-5p network

PLoS Pathogens, 2019
Kaposi’s sarcoma (KS), a highly disseminated tumor of hyperproliferative spindle endothelial cells, is the most common AIDS-associated malignancy caused by infection of Kaposi’s sarcoma-associated herpesvirus (KSHV).
Wan Li, Qingxia Wang, Qi Feng, Fei Wang, Q. Yan, Shou-Jiang Gao, Chun Lu   +6 more
semanticscholar   +1 more source

Virus-Mediated Alterations in miRNA Factors and Degradation of Viral miRNAs by MCPIP1.

PLoS Biology, 2016
Kaposi's sarcoma-associated herpesvirus (KSHV), the causative agent of Kaposi's sarcoma, encodes 25 mature viral miRNAs. MCP-1-induced protein-1 (MCPIP1), a critical regulator of immune homeostasis, has been shown to suppress miRNA biosynthesis via ...
Christine Happel, Dhivya Ramalingam, Joseph M Ziegelbauer   +2 more
doaj   +1 more source

Evidence for Kaposi Sarcoma Originating from Mesenchymal Stem Cell through KSHV-induced Mesenchymal-to-Endothelial Transition.

Cancer Research, 2018
The major transmission route for Kaposi sarcoma-associated herpesvirus (KSHV) infection is the oral cavity through saliva. Kaposi sarcoma (KS) frequently occurs in the oral cavity in HIV-positive individuals and is often the first presenting sign of AIDS.
Yuqing Li, C. Zhong, Dawei Liu, Wenjing Yu, Weikang Chen, Yan Wang, S. Shi, Yan Yuan   +7 more
semanticscholar   +1 more source

Molecular detection and genotyping of human herpes virus 8 in blood donors in Congo

Вопросы вирусологии
Objectives. Human herpesvirus 8 (HHV8) is rarely studied in Congo, despite its prevalence in Africa. Among healthy individuals, HHV-8 does not always lead to a life-threatening infection; however, in immunocompromised individuals, it could lead to more ...
Patrina Joseph Iloukou, Anicet Luc Magloire Boumba, Dorine Florence Luthera Ngombe, Norvi Rigobert Bienvenu Massengo, Gervillien Arnold Malonga, Donatien Moukassa, Moulay Mustapha Ennaji   +6 more
doaj   +1 more source