Results 71 to 80 of about 22,488 (214)

The Inflammatory Kinase MAP4K4 Promotes Reactivation of Kaposi's Sarcoma Herpesvirus and Enhances the Invasiveness of Infected Endothelial Cells [PDF]

, 2013
Kaposi's sarcoma (KS) is a mesenchymal tumour, which is caused by Kaposi's sarcoma herpesvirus (KSHV) and develops under inflammatory conditions. KSHV-infected endothelial spindle cells, the neoplastic cells in KS, show increased invasiveness, attributed
A Beeghly-Fadiel, A Cuenda, A Greenhough, A Grundhoff, A Jarviluoma, A Kitzis, A Liacini, A Sodhi, AE Carpenter, AM Manning, AW Liu, B Ensoli, B Fingleton, BD Shelby, Blossom Damania, BW Ozanne, C Grossmann, C Yan, CJ Edgell, CS Collins, D Blankaert, D Briot, D Ganem, D Ganem, D Qin, D Rott, Darya A. Haas, DF Legler, DH Kedes, DL Simmons, DM Lukac, E Deutsch, EA Jaffe, EI Deryugina, F Cheng, F Cheng, F Lu, FA Mack, FQ Wang, G Giraldo, GJ Tesz, Guntram Büsche, György Keri, H Chang, H Katano, H Lu, H Nagase, H Pan, H Sheng, H Zhu, HJ Ra, I Nindl, J An, J Nicholas, J Soulier, J Vieira, J Westermarck, J Xie, J Xie, JA Mengshol, JC Boehm, JC Lee, JC Lee, Jessica Rückert, JG Kang, JJ Liang, JL Ambrus, JN Kline, JN Martin, JR Jackson, JW Said, JW Tjiu, K Bouzakri, K Lan, K Wisithphrom, Kiran Bala, KJ Sales, KQ Hu, KR Alkharsah, KV Guntur, L Pantanowitz, L Rosano, LC Meade-Tollin, LW Qian, M Aouadi, M Baumgartner, M Chatterjee, M Khyatti, M Paulose-Murphy, M Pouliot, M Rincon, M Tsujii, MA Fabian, Magdalena Weidner-Glunde, ME Janelle, MH Qiu, Michael Kracht, MM Brinkmann, Modester Damas, MR Bongiorno, MW Karaman, N Dupin, N Edraki, N Otsu, N Sharma-Walia, N Sharma-Walia, N Yamamoto, Oliver Dittrich-Breiholz, P Ben-Av, P Pyakurel, PJ Dillon, PP Naranatt, PP Naranatt, PS Moore, PW Ford, R Ala-Aho, RE Harris, RW Humphrey, S Kati, S Milligan, S Sadagopan, Semra Kati, Silvia Gramolelli, SJ Gao, SK Lee, SM Gregory, Susann Santag, SX Han, T Fournier, T Gatanaga, T May, T Shiomi, T Simonart, TB Campbell, TF Gallagher, TF Schulz, Thomas F. Schulz, TL Symensma, UR Hengge, UR Hengge, V Fonsato, V Knauper, V Puri, W Greene, W Yue, WW Au, X Tang, Y Chang, Y Liang, Y Xu, YH Chung, Z Yao, Zoltan Varga   +152 more
core   +1 more source

Neuroinflammation as a result of non‐neurotropic herpesvirus infection

Immunology &Cell Biology, EarlyView.
Atypical memory B cells (ABCs) might stimulate autoreactive T cells to cause neuroinflammation and CNS myeloid cell activation during MS. Abstract The non‐neurotropic Epstein Barr virus (EBV) has been suggested to initiate the prodromal phase of multiple sclerosis (MS), often years before the first clinical symptoms. This review discusses mechanisms by
Christian Münz
wiley   +1 more source

Macrophages drive KSHV B cell latency

Cell Reports, 2023
Kaposi's sarcoma herpesvirus (KSHV) establishes lifelong infection and persists in latently infected B cells. Paradoxically, in vitro B cell infection is inefficient, and cells rapidly die, suggesting the absence of necessary factor(s). KSHV epidemiology unexpectedly mirrors that of malaria and certain helminthic infections, while other herpesviruses ...
Szymula, Agnieszka, Samayoa-Reyes, Gabriela, Ogolla, Sidney, Liu, Bing, Li, Shijun, George, Athira, Sciver, Nicholas Van, Rochford, Rosemary, Simas, J. Pedro, Kaye, Kenneth M.   +9 more
openaire   +5 more sources

Disease Progression Mediated by Egr-1 Associated Signaling in Response to Oxidative Stress [PDF]

, 2012
When cellular reducing enzymes fail to shield the cell from increased amounts of reactive oxygen species (ROS), oxidative stress arises. The redox state is misbalanced, DNA and proteins are damaged and cellular transcription networks are activated.
Abdulkadir, Abdulkadir, Aggeli, Arsenian, Banks, Baron, Bedadala, Bedard, Bjelakovic, Bjelakovic, Bonventre, Brand, Calogero, Cao, Cao, Chang, Chen, Christy, Christy, Cramer, Datta, Dixit, Dixit, Dyson, Dyson, Eidelman, Elisabeth Deindl, Eto, Eto, Fahmy, Fahmy, Feldman, Forsberg, Förstermann, Gao, Gashler, Hallahan, Halliwell, Harja, Harman, Harrison, Hasan, Hasan, Hebert, Heo, Hill, Hirata, Huang, Irani, Iyoda, Izumi, Judith-Irina Pagel, Katsarou, Kawamura, Khachigian, Khachigian, Konishi, Lee, Liao, Lim, Lukac, Marais, Meira, Nishi, Nose, Nose, Nozik-Grayck, Ohba, Ouellette, Pagel, Paron, Pavletich, Peskin, Pines, Preston, Radisky, Sakamoto, Sattler, Schwachtgen, Sies, Sies, Stuart, Sudenga, Tell, Tell, Tell, Tell, Terashima, Treisman, Tsai-Morris, Vickers, Vivekananthan, Wang, Whitmarsh, Yan, Yan, Yang, Yang, Ye, Yu   +99 more
core   +2 more sources

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Age of Infection with Kaposi Sarcoma-Associated Herpesvirus and Subsequent Antibody Values Among Children in Uganda. [PDF]

, 2018
We investigated associations between Kaposi sarcoma-associated herpesvirus (KSHV) seroconversion age and KSHV antibody values in Ugandan children. Every annual delay in KSHV seroconversion age was associated with a reduction of 19% (P < 0.0001) in K8.1 ...
Cose, Stephen, Elliott, Alison, Labo, Nazzarena, Miley, Wendell, Nalwoga, Angela, Newton, Robert, Whitby, Denise   +6 more
core   +1 more source

HHV‐8/KSHV in Solid Organ Transplantation: Current Gaps of Knowledge and Future Directions

Transplant Infectious Disease, EarlyView.
Risk mitigation strategies, including donors/recipients screening, DNAemia monitoring in recipients at risk, CNI‐to‐mTOR inhibitors switch, antivirals, and rituximab for KICS, may mitigate the impact of HHV‐8/KSHV infection in SOT. This review provides an update on KICS, identifies research gaps, and summarizes advances in screening and management ...
Alessandra Mularoni, Andrea Cona, Malgorzata Mikulska, Francesca Pecoraro, Carlotta Piazza, Elda De Vita, Giada Pietrosi, Matteo Bulati, Tiziana Lazzarotto, Mario Luppi   +9 more
wiley   +1 more source

Study of variable stars in the MOA data base: long-period red variables in the Large Magellanic Cloud [PDF]

, 2001
One hundred and forty six long-period red variable stars in the Large Magellanic Cloud (LMC) from the three year MOA project database were analysed. A careful periodic analysis was performed on these stars and a catalogue of their magnitudes, colours ...
Alard, Alcaino, Barthes, Becker, Bedding, C. Noguchi, Caputo, D.J. Sullivan, F. Abe, Feast, Feast, Feast, Feast, G.R. Nankivell, Glass, Glass, H. Sato, Hearnshaw, Holtzman, Hughes, I.A. Bond, J. Jugaku, J. Skuljan, J.B. Hearnshaw, K. Masuda, K. Ohnishi, Kato, Kienzle, Kurochkin, Leavitt, M. Honda, M. Honma, M. Reid, M. Sekiguchi, M. Takeuti, M. Yoshizawa, N.J. Rattenbury, Noda, P.C.M. Yock, P.M. Kilmartin, R. Yamada, R.J. Dodd, S. Kabe, S. Noda, S. Wilkinson, Schechter, Smak, Stellingwerf, T. Nakamura, T. Sumi, T. Yanagisawa, Takeuti, To. Saito, Trams, Walker, Whitelock, Whitelock, Whitelock, Wood, Wood, Y. Kan-ya, Y. Kato, Y. Matsubara, Y. Muraki, Y. Watase, Yanagisawa   +65 more
core   +2 more sources

Liquid–Liquid Phase Separation in Viral Infection and Immunology

MedComm, Volume 7, Issue 4, April 2026.
LLPS organizes viral replication and antiviral immunity. Viruses hijack LLPS to form replication factories and evade immune sensors, while hosts assemble LLPS‐driven signaling hubs (e.g., MAVS, RIG‐I, and SGs) to amplify interferon responses. Targeting these condensate interfaces offers novel therapeutic strategies against infectious diseases ...
Jiuzhi Xu, Lan Bai, Bin Wang, Hai Song, Long Zhang, Fangfang Zhou   +5 more
wiley   +1 more source

METTL16 controls Kaposi’s sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle

Cell Death and Disease, 2023
Oncogenic Kaposi’s sarcoma-associated herpesvirus (KSHV) consists of latent and lytic replication phases, both of which are important for the development of KSHV-related cancers.
Xinquan Zhang, Wen Meng, Jian Feng, Xinghong Gao, Chao Qin, Pinghui Feng, Yufei Huang, Shou-Jiang Gao   +7 more
doaj   +1 more source