Results 131 to 140 of about 42,072 (228)

Serum Inflammatory Markers and Dietary Inflammatory Index in Obese Individuals With Fatty Liver Disease: A Case–Control Study

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.
Our findings underscore the role of inflammation in the pathophysiology of fatty liver disease among obese individuals. Elevated CRP levels highlight potential targets for intervention. ABSTRACT Background Fatty liver disease is common among obese individuals and is closely linked to chronic low‐grade inflammation.
Faezeh Tejareh, Laleh Payahoo, Seyed Ali Keshavarz   +2 more
wiley   +1 more source

Viral-Directed Augmentation of Kupffer Cell Cross-Presentation Provokes Antitumor Immunity Against Liver Metastasis. [PDF]

Adv Sci (Weinh)
Chen C, Zhang Q, Li J, Zhou X, Gao D, Li L, Huang D, Wang J, Zeng Z.   +8 more
europepmc   +1 more source

GPAT3 regulates the synthesis of lipid intermediate LPA and exacerbates Kupffer cell inflammation mediated by the ERK signaling pathway. [PDF]

Cell Death Dis, 2023
Fan G, Li Y, Zong Y, Suo X, Jia Y, Gao M, Yang X.   +6 more
europepmc   +1 more source

Association Between Dietary Tea Consumption and Non‐Alcoholic Fatty Liver Disease: A Systematic Review and Meta‐Analysis

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Non‐Alcoholic Fatty Liver Disease (NAFLD) is a significant global health concern linked with metabolic syndrome, affecting approximately 25% of the global population. It leads to severe liver complications and has limited effective pharmacological treatments. Tea, known for its bioactive compounds such as flavonoids and polyphenols,
Amogh Verma, Ranjana Sah, Rachana Mehta
wiley   +1 more source

Divergent Hepatic and Adipose Tissue Effects of Kupffer Cell Depletion in a Male Rat Model of Metabolic-Associated Steatohepatitis. [PDF]

Biology (Basel)
Wiszniewski M, Mori D, Sanchez Puch SI, Martinez Calejman C, Cymeryng CB, Repetto EM.   +5 more
europepmc   +1 more source

Ophiopogon Polysaccharide Liposome Regulated the Immune Activity of Kupffer Cell through miR-4796. [PDF]

Int J Mol Sci, 2022
Cui J, Pan X, Duan X, Ke L, Song X, Zhang W, Ma W, Liu Y, Fan Y.   +8 more
europepmc   +1 more source

Companion Diagnostics in Clinical Therapy: Current Applications and Future Directions

MedComm, Volume 7, Issue 3, March 2026.
Companion diagnostics use biomarker‐based assays to stratify patients for precision therapies, improving outcomes while reducing ineffective treatment and side effects. This review summarizes the evolution, regulatory landscape, clinical applications, and technological platforms of CDx, highlighting their role in biomarker‐driven precision therapy.
Yuesong Wu, Rou Xue, Xiangwen Luo, Jiangnan Liao, Zongbo Zhang, Jinhai Deng, Teng Liu, Xin Li, Zhe‐Sheng Chen, Mingzhu Yin   +9 more
wiley   +1 more source

Chronic Waterborne Exposure to Polystyrene Microplastics Induces Kupffer Cell Polarization Imbalance and Hepatic Lipid Accumulation. [PDF]

FASEB J
Li T, Yao Z, Huang Y, Li R, Zhang L, Chen R, Gu W.   +6 more
europepmc   +1 more source

Pioglitazone Modifies Kupffer Cell Function and Protects against Escherichia coli-Induced Bacteremia in Burned Mice. [PDF]

Int J Mol Sci, 2022
Miyazaki H, Kinoshita M, Nakashima H, Nakamura S, Saitoh D.   +4 more
europepmc   +1 more source

Remodeling the Inflammatory Microenvironment: Nanomaterial‐Based Targeted Strategies for Systemic Lupus Erythematosus and Lupus Nephritis

Small Science, Volume 6, Issue 3, March 2026.
Current treatments for severe lupus nephritis are limited by side effects due to poor drug targeting. This review explores how smart nanomaterials—like liposomes and biomimetic carriers—can precisely deliver drugs to overactive immune cells and the kidneys. These nanotherapeutics enhance efficacy, reduce toxicity, and enable combination strategies. The
Cheng Zhou, Jiayi Li, Jian Zhang, Haifeng Wang, Haitao Lu, Shunlai Shang, Wenge Li   +6 more
wiley   +1 more source