Kynurenic acid and its analogues
Tryptophan serves as a rate-limiting essential amino acid and a distinctive building block of peptides and proteins. Many immune system cells are known to be regulated by tryptophan metabolites. Kynurenic acid, an endogenous byproduct of tryptophan metabolism, functions as a wide-spectrum inhibitor of excitatory amino acid receptors and may serve as a ...
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Biochemical Regulation of Brain Kynurenic Acid Synthesis and Inhibition in Rats Is Sensitive to the Time of Day. [PDF]
Wright CJ +5 more
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Biochemical and Pharmacological Studies on Kynurenic Acid Metabolism in the <i>Helix pomatia</i>-Snail Model of Learning and Memory. [PDF]
Baran H, Kronsteiner C.
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Activation of the Ahr-IL-6 Axis by Kynurenic Acid Promotes Bone Marrow-Derived MSC Expansion. [PDF]
Nguyen CH +6 more
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Investigation of the Impact of Tryptophan-Metabolizing Enzymes and Kynurenic Acid on Antibody-Mediated Glomerulonephritis. [PDF]
Umeda R +10 more
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Kynurenic Acid/GPR35 Signaling Protects the Infarcted Heart by Suppressing Macrophage mtDNA-Triggered cGAS-STING Activation. [PDF]
Mao Y +10 more
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Kynurenic acid signaling expands in human and nonhuman primates and impairs dorsolateral prefrontal cortical cognition that is key to mental illness. [PDF]
Yang S +12 more
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HCAR3 and Kynurenic Acid in Cancer: A Promising Axis of Immunometabolic Regulation or a Scientific Mirage? [PDF]
Walczak K, Krasowska D.
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