Results 111 to 120 of about 19,359 (226)
Journal of Diabetes Research, 2019 Patients with diabetes mellitus (DM) type 1 and 2 are at a higher risk of cognitive decline and dementia; however, the underlying pathology is poorly understood.
Iwona Chmiel-Perzyńska +5 more
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The orphan receptor GPR35 contributes to angiotensin II–induced hypertension and cardiac dysfunction in mice [PDF]
, 2018 BACKGROUND: The orphan receptor G protein–coupled receptor 35 (GPR35) has been associated with a range of diseases, including cancer, inflammatory bowel disease, diabetes, hypertension, and heart failure.
Divorty, Nina +3 more
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FASEB BioAdvancesMyocardial ischemia causes the release of bradykinin, which activates afferent nerve endings in the ventricular epicardium. This elicits a sympathetically mediated increase in arterial pressure and heart rate, referred to as the cardiogenic sympathetic ...
Matthew R. Zahner +2 more
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Inflammation and immunity in schizophrenia: implications for pathophysiology and treatment. [PDF]
, 2014 Complex interactions between the immune system and the brain might have important aetiological and therapeutic implications for neuropsychiatric brain disorders.
Cousins, Lesley +5 more
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Novel Regulation of Cortical Acetylcholine Release and Cognitive Behavior [PDF]
, 2008 SBS Undergraduate Research GrantASC Undergraduate Research Scholarship CompetitionDean's Undergraduate Research FundABSTRACT There is an evolving literature demonstrating the ability of non-neuronal cells to regulate the release of traditional ...
Gardner, Kristen
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Kynurenic acid and its analogues
Journal of Medical Pharmaceutical and Allied SciencesTryptophan serves as a rate-limiting essential amino acid and a distinctive building block of peptides and proteins. Many immune system cells are known to be regulated by tryptophan metabolites. Kynurenic acid, an endogenous byproduct of tryptophan metabolism, functions as a wide-spectrum inhibitor of excitatory amino acid receptors and may serve as a ...
openaire +1 more source
Regulation of prefrontal glutamate by the endogenous neuromodulator kynurenic acid as measured by rapid electrochemistry: relevance to schizophrenia [PDF]
, 2010 Schizophrenia is one of the most debilitating neuropsychiatric disorders, with a prevalence of approximately 1% worldwide. Symptoms include impairing deficits in cognitive processes (e.g., working memory, attention, and cognitive flexibility) which are ...
Campbell, Andrew
core
Tryptophan metabolites clearance in hemodialyzed patients
Amino AcidsHemodialysis (HD) and hemodiafiltration (HDF) procedures have limited efficacy regarding removal of selected toxins. Tryptophan (Trp) metabolites formed through the kynurenine (KYN) pathway are known to contribute to kidney failure (KF) complications ...
Izabela Zakrocka +8 more
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MetabolitesBackground: The early nutritional metabolism of piglets is intimately associated with the regulation of immune function, and amino acids play a crucial role in modulating the fate and function of porcine immune cells, especially macrophages. However, the
Meimei Zhang +3 more
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