Results 101 to 110 of about 2,696,733 (168)

Kynurenic acid attenuates experimental allergic rhinitis: Evidence for AhR-associated regulation of mucosal immune homeostasis. [PDF]

PLoS One
Gheymoumi N, Shayesteh S, Sharifi F, Amiri-Andebili M, Gheymoumi H.   +4 more
europepmc   +1 more source

Endogenous kynurenic acid and schizophrenia : physiological and pharmacological aspects [Elektronisk resurs]

, 2006
Kynurenic acid is a glutamate receptor antagonist with a preferential action at the glycine/Dserine site of the N-methyl-D-aspartic acid (NMDA) receptor. The compound is a metabolite of tryptophan and is synthesized in astrocytes.
Schwieler, L,
core  

Glutamatergic mechanisms in schizophrenia : role of endogenous kynurenic acid [Elektronisk resurs]

, 2005
Kynurenic acid, a tryptohan metabolite synthesised in astrocytes, is an endogenous antagonist at glutamate receptors, in particular it blocks the glycine site of the (NMDA)-receptor, and at the a7* nicotinic receptor.
Nilsson, LK,
core  

<i>GRIA3</i>: proposal for a neuroimmune role linking infection, stress, chronic disorders and the activity of kynurenic acid. [PDF]

Front Cell Neurosci
Stone TW, Clanchy FIL, Williams RO.
europepmc   +1 more source

Kynurenic acid mediates epicardial fat-induced lymphatic metabolic dysfunction in atrial fibrillation. [PDF]

Nat Commun
Takahashi M, Abe I, Yoshida N, Katoh D, Fujita D, Goto S, Yamasaki H, Ko T, Jiang Y, He Y, Ito S, Harada T, Takano M, Sato H, Kondo H, Fukui A, Teshima Y, Sako H, Ohta K, Miyamoto S, Yamauchi T, Nomura S, Takeda N, Komuro I, Takahashi N.   +24 more
europepmc   +1 more source

Astroglial disinhibition of cortical circuits disrupts cognition via kynurenic acid in mice. [PDF]

Nat Commun
Beilmann V, Furrer J, Schalbetter SM, Schaer R, Tiziani E, Ferrari KD, Herrero F, Heeb C, von Faber-Castell A, Condrau J, Weber-Stadlbauer U, Wyss MT, Saab AS, Beggiato S, Meyer U, Weber B, Notter T.   +16 more
europepmc   +1 more source

Targeted intestinal ROS scavenging alleviated rheumatoid arthritis by microbial metabolite kynurenic acid mediated Treg/Th17 balance through AhR pathway activation. [PDF]

Gut Microbes
Ling Z, Xiang T, Yang C, Zhang D, You Y, Xiao S, Xie L, Tan J, Dai Q, Huang G, Sun D, Luo F, Chen Y.   +12 more
europepmc   +1 more source

Biochemical Regulation of Brain Kynurenic Acid Synthesis and Inhibition in Rats Is Sensitive to the Time of Day. [PDF]

ACS Chem Neurosci
Wright CJ, Buck SA, Milosavljevic S, Lewis AM, Wagner NTJ, Pocivavsek A.   +5 more
europepmc   +1 more source

<i>Streptococcus anginosus</i>-associated kynurenic acid drives PD-1 blockade resistance through an ITGA2-mTOR-CTSV axis in gastric cancer. [PDF]

J Immunother Cancer
Ren Y, Yu X, Jiang J, Luo J, Zhao C, Mao X, Xi Y, He J, Yu C, Hu Y.   +9 more
europepmc   +1 more source

Biochemical and Pharmacological Studies on Kynurenic Acid Metabolism in the <i>Helix pomatia</i>-Snail Model of Learning and Memory. [PDF]

Biomolecules
Baran H, Kronsteiner C.
europepmc   +1 more source