Cytotoxic Effects of Kynurenic Acid and Quinaldic Acid in Hepatocellular Carcinoma (HepG2) Cell Line
Proceedings, 2017 Kynurenic acid (KYNA), tryptophan metabolite synthesized in the kynurenine pathway, is present in human body fluids as well as in variety of foods, herbal medicines and honeybee derived foodstuffs.
Pınar Atalay Dündar +1 more
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Effects of inflammation on the kynurenine pathway in schizophrenia — a systematic review
Journal of Neuroinflammation, 2020 Background In the last decade, there has been growing evidence that an interaction exists between inflammation and the kynurenine pathway in schizophrenia.
Bruno Pedraz-Petrozzi +3 more
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Substance P-Driven Feed-Forward Inhibitory Activity in the Mammalian Spinal Cord [PDF]
, 2005 In mammals, somatosensory input activates feedback and feed-forward inhibitory circuits within the spinal cord dorsal horn to modulate sensory processing and thereby affecting sensory perception by the brain.
Terumasa Nakatsuka +9 more
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Xanthurenic acid and its rôle in the trytophane metabolism of pyroxidine-deficient rats [PDF]
, 1943 In a previous publication (1) the isolation of a green pigment from the urine of pyridoxine-deficient rats was described. The green pigment was shown to be the product of a reaction between ferric ammonium sulfate or other ferric salts and a compound ...
Haagen-Smit, A. J. +2 more
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Simultaneous release of glutamate and acetylcholine from single magnocellular "cholinergic" basal forebrain neurons [PDF]
, 2006 Basal forebrain (BF) neurons provide the principal cholinergic drive to the hippocampus and cortex. Their degeneration is associated with the cognitive defects of Alzheimer's disease. Immunohistochemical studies suggest that some of these neurons contain
Abogadie, FC, Allen, TGJ, Brown, DA
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Physicochemical Characterization of Kynurenine Pathway Metabolites
AntioxidantsThe kynurenine pathway is a significant metabolic route involved in the catabolism of tryptophan, producing various bioactive metabolites with crucial roles as antioxidants in immune regulation and neurobiology.
Luca Buzásy +7 more
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Cerebrospinal fluid biomarkers in twins with schizophrenia and bipolar disorder [PDF]
, 2015 Previously identified cerebrospinal fluid (CSF) biomarkers were studied in 37 twins with schizophrenia or bipolar disorder to determine their genetic and environmental properties.
Johansson, Viktoria
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npj Parkinson's DiseaseWe previously demonstrated that kynurenine pathway (KP) dysregulation associates with Parkinson’s disease (PD) and its symptoms. Here, we profiled 16 KP-related markers in a second, independent cohort; plasma: n = 202 (116 PD (“OFF”), 86 controls); CSF ...
Leslie C. Jellen +10 more
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NMDA antagonists as Parkinson's disease therapy: disseminating the evidence [PDF]
, 2014 Förskolans fysiska inomhusmiljö ska vara stimulerande och locka barnen till lek och lärande, och det kräver av förskollärare att de ständigt reflekterar över och bearbetar den som en del av sitt arbete.
Majláth, Zsófia, Vécsei, László
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Inflammation and immunity in schizophrenia: implications for pathophysiology and treatment. [PDF]
, 2014 Complex interactions between the immune system and the brain might have important aetiological and therapeutic implications for neuropsychiatric brain disorders.
Cousins, Lesley +5 more
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