Results 171 to 180 of about 19,359 (226)

Elevated serum kynurenic acid in individuals with first-episode psychosis and insufficient response to antipsychotics. [PDF]

open access: yesSchizophrenia (Heidelb)
Hatzimanolis A   +10 more
europepmc   +1 more source

Computed Tomography and Fluorescence Spectroscopy Blood Plasma Analysis Study for Kynurenic Acid as a Diagnostic Approach to Chronic Coenurosis in Sheep. [PDF]

open access: yesLife (Basel)
Olar LE   +11 more
europepmc   +1 more source

The Tryptophan Metabolite Indole-3-Propionic Acid Raises Kynurenic Acid Levels in the Rat Brain In Vivo. [PDF]

open access: yesInt J Tryptophan Res
Sathyasaikumar KV   +7 more
europepmc   +1 more source

Ortho-quinone methide driven synthesis of kynurenic acid lactams. [PDF]

open access: yesRSC Adv
Sárik JR   +4 more
europepmc   +1 more source

Studies on the metabolism of kynurenic acid Enzymic formation of 7,8-dihydroxykynurenic acid from kynurenic acid

open access: yesStudies on the metabolism of kynurenic acid Enzymic formation of 7,8-dihydroxykynurenic acid from kynurenic acid
openaire  
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The Janus-face kynurenic acid

Journal of Neural Transmission, 2008
Kynurenic acid is an endogenous product of the tryptophan metabolism. Studies on the mechanism of its action have revealed that kynurenic acid at high concentrations is a competitive antagonist of the N-methyl-D-aspartate receptor and acts as a neuroprotectant in different neurological disorders.
Rózsa Éva   +3 more
openaire   +6 more sources

Kynurenic acid antagonists and kynurenine pathway inhibitors

Expert Opinion on Investigational Drugs, 2001
The kynurenine pathway accounts for the metabolism of around 80% of non-protein tryptophan metabolism. It includes both an agonist (quinolinic acid) at NMDA receptors and an antagonist (kynurenic acid). Since their discovery, there has been a major development of kynurenic acid analogues as neuroprotectants for the treatment of stroke and ...
Trevor W Stone
openaire   +4 more sources

Kynurenic Acid Monohydrate

Acta Crystallographica Section C Crystal Structure Communications, 1996
In the structure of the title compound, 4-hydroxy-2- quinolinecarboxylic acid monohydrate, C 10 H 7 NO 3 .H 2 O, the carboxyl group is ionized and the ring N atom is protonated giving it a positive charge. The molecule is almost planar. The crystal structure is stabilized both by intermolecular O-H...O and N-H...O hydrogen bonds involving the solvated ...
N. Okabe, J. Miura, A. Shimosaki
openaire   +1 more source

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