Results 171 to 180 of about 19,359 (226)
Elevated serum kynurenic acid in individuals with first-episode psychosis and insufficient response to antipsychotics. [PDF]
Hatzimanolis A +10 more
europepmc +1 more source
Computed Tomography and Fluorescence Spectroscopy Blood Plasma Analysis Study for Kynurenic Acid as a Diagnostic Approach to Chronic Coenurosis in Sheep. [PDF]
Olar LE +11 more
europepmc +1 more source
Effect of kynurenic acid on enzymatic activity of the DNA base excision repair pathway in specific areas of the sheep brain. [PDF]
Młotkowska P +3 more
europepmc +1 more source
The Tryptophan Metabolite Indole-3-Propionic Acid Raises Kynurenic Acid Levels in the Rat Brain In Vivo. [PDF]
Sathyasaikumar KV +7 more
europepmc +1 more source
Ortho-quinone methide driven synthesis of kynurenic acid lactams. [PDF]
Sárik JR +4 more
europepmc +1 more source
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Journal of Neural Transmission, 2008
Kynurenic acid is an endogenous product of the tryptophan metabolism. Studies on the mechanism of its action have revealed that kynurenic acid at high concentrations is a competitive antagonist of the N-methyl-D-aspartate receptor and acts as a neuroprotectant in different neurological disorders.
Rózsa Éva +3 more
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Kynurenic acid is an endogenous product of the tryptophan metabolism. Studies on the mechanism of its action have revealed that kynurenic acid at high concentrations is a competitive antagonist of the N-methyl-D-aspartate receptor and acts as a neuroprotectant in different neurological disorders.
Rózsa Éva +3 more
openaire +6 more sources
Kynurenic acid antagonists and kynurenine pathway inhibitors
Expert Opinion on Investigational Drugs, 2001The kynurenine pathway accounts for the metabolism of around 80% of non-protein tryptophan metabolism. It includes both an agonist (quinolinic acid) at NMDA receptors and an antagonist (kynurenic acid). Since their discovery, there has been a major development of kynurenic acid analogues as neuroprotectants for the treatment of stroke and ...
Trevor W Stone
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INCREASED KYNURENIC ACID LEVELS IN HUNTINGTON'S DISEASE
The Lancet, 1988J H, Connick +3 more
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Acta Crystallographica Section C Crystal Structure Communications, 1996
In the structure of the title compound, 4-hydroxy-2- quinolinecarboxylic acid monohydrate, C 10 H 7 NO 3 .H 2 O, the carboxyl group is ionized and the ring N atom is protonated giving it a positive charge. The molecule is almost planar. The crystal structure is stabilized both by intermolecular O-H...O and N-H...O hydrogen bonds involving the solvated ...
N. Okabe, J. Miura, A. Shimosaki
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In the structure of the title compound, 4-hydroxy-2- quinolinecarboxylic acid monohydrate, C 10 H 7 NO 3 .H 2 O, the carboxyl group is ionized and the ring N atom is protonated giving it a positive charge. The molecule is almost planar. The crystal structure is stabilized both by intermolecular O-H...O and N-H...O hydrogen bonds involving the solvated ...
N. Okabe, J. Miura, A. Shimosaki
openaire +1 more source

