Results 281 to 290 of about 55,792 (321)

AHR Agonist ITE Boosted PD1 Antibody's Effects by Inhibiting Myeloid-Derived Cells Suppressive Cells in an Orthotopic Mouse Glioma Model. [PDF]

Pharmaceuticals (Basel)
Gong P, Zhao L, Ma Y, Shu Q, Sun H, Lu J, Meng F, Wan F.   +7 more
europepmc   +1 more source

Essential amino acids and branched-chain amino acids are associated with skeletal muscle and inflammatory parameters in older age. [PDF]

Biogerontology
Li CWD, Herpich C, Haß U, Kochlik B, Weber D, Grune T, Norman K.   +6 more
europepmc   +1 more source

Parental kynurenine 3-monooxygenase genotype in mice directs sex-specific behavioral outcomes in offspring. [PDF]

Biol Sex Differ
Milosavljevic S, Piroli MV, Sandago EJ, Piroli GG, Smith HH, Beggiato S, Frizzell N, Pocivavsek A.   +7 more
europepmc   +1 more source

The role of the tryptophan metabolites in gut microbiota-brain axis and potential treatments: a focus on ischemic stroke. [PDF]

Front Pharmacol
Qin N, Xie X, Deng R, Gao S, Zhu T.
europepmc   +1 more source

Exercise training restores longevity-associated tryptophan metabolite 3-hydroxyanthranilic acid levels in middle-aged adults. [PDF]

Acta Physiol (Oxf)
Joisten N, Reuter M, Rosenberger F, Venhorst A, Kupjetz M, Walzik D, Schenk A, McCann A, Ueland PM, Meyer T, Zimmer P.   +10 more
europepmc   +1 more source

Genetic disruption of leucine rich repeat transmembrane protein 4 like 1 induces a pro-social behavioural phenotype in zebrafish

Hillman C, Petracco G, Fontana BD, Scaia MF, Dalla-Vecchia E, Wetton JH, Norton WH, Parker M, Reichmann F.   +8 more
europepmc   +1 more source

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Kynurenines and headache

Journal of Neural Transmission, 2011
In parallel to serotonin synthesis, the major route of tryptophan catabolism is the kynurenine pathway, which produces neuroactive metabolites. Among these substances, kynurenic acid has potential neuroprotective action blocking glutamate release and glutamatergic neurotransmission.
Párdutz Árpád, Fejes-Szabó Annamária, Bohár Zsuzsanna, Tar Lilla, Toldi József, Vécsei László   +5 more
openaire   +4 more sources

Advances in kynurenine analysis

Clinica Chimica Acta, 2023
Kynurenine, the first product of tryptophan degradation via the kynurenine pathway, has become one of the most frequently mentioned biomarkers in recent years. Its levels in the body indicate the state of the human physiology. Human serum and plasma are the main matrixes used to evaluate kynurenine levels and liquid chromatography is the dominant ...
K, Mrštná, L Kujovská, Krčmová, F, Švec   +2 more
openaire   +2 more sources

Systemic Perturbations in Amine and Kynurenine Metabolism Associated with Acute SARS-CoV-2 Infection and Inflammatory Cytokine Responses

Journal of Proteome Research, 2021
We performed quantitative metabolic phenotyping of blood plasma in parallel with cytokine/chemokine analysis from participants who were either SARS-CoV-2 (+) (n = 10) or SARS-CoV-2 (-) (n = 49).
N. Lawler, Nicola Gray, Torben Kimhofer, B. Boughton, M. Gay, Rongchang Yang, Aude-Claire Morillon, Sung-Tong Chin, Monique J. Ryan, S. Begum, Sze-How Bong, J. Coudert, D. Edgar, E. Raby, S. Pettersson, T. Richards, E. Holmes, Luke Whiley, J. Nicholson   +18 more
semanticscholar   +1 more source