Results 101 to 110 of about 13,672,018 (258)

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source

L-Arginine transport kinetics.

, 2013
L-Arginine transport kinetics (3 μCi/mL L-[3H] arginine, 1 minute, 37°C) in HUVECs cultured (8 hours) without (–NBTI; a, c) or with (+NBTI; b, d) 10 μmol/L nitrobenzylthioinosine (NBTI).
Luis Sobrevia (295521), Fabián Pardo (295519), Andrea Leiva (295520), Enrique Guzmán-Gutiérrez (295518), Marcelo González (314858), Francisco Westermeier (314855), Carlos Salomón (314856)   +6 more
core   +1 more source

Antibacterial Effect of Silver Nanoparticles along with L-Arginine against P. aeruginosa

Medical Laboratory Journal, 2017
Background and Objectives: Nowadays, the prevalence of multidrug-resistant pathogens such as Pseudomonas aeruginosa is increasing worldwide. Many studies have been seeking new treatment strategies to treat infections caused by these microorganisms ...
Mina Parsa, Malahat Ahmadi, Habib Dastmalchi, Aliasghar Tehrani   +3 more
doaj  

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

N(G)-monomethyl-L-arginine inhibits thrombin-stimulated production of cyclic GMP in cultured porcine aortic endothelial cells

, 1990
The production of endothelium-derived nitric oxide evoked by thrombin in cultural porcine aortic endothelial cells was assessed indirectly by changes in cyclic GMP levels.
Vanhoutte, PM, Moncada, S, Schini, VB
core  

L-arginine metabolism in breast cancer: mechanisms and therapeutic targets

Frontiers in Oncology
Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer-related death among women worldwide. It is a highly heterogeneous disease that can be divided into different molecular subtypes, which differ in morphology, prognosis ...
Antonia Röglin, Rainer Böger, Juliane Hannemann   +2 more
doaj   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

Increased L-citrulline/L-arginine plasma ratio in severe preeclampsia.

, 2000
To evaluate nitric oxide (NO) production in patients with pregnancy-induced hypertension or preeclampsia and in controls.Four groups of pregnant women were included: 17 patients with pregnancy-induced hypertension, ten with mild or moderate preeclampsia,
NERI, Isabella, C. Benedetto, VOLPE, Annibale, FACCHINETTI, Fabio, L. Marozio, M. Giarola   +5 more
core   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Polyphenol‐Inspired Materials for Agricultural Applications

Advanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu, Omid Mazaheri, Zhixing Lin, Tianzheng Wang, Jingqu Chen, Yuang Gu, Xia Liang, Deli Chen, Frank Caruso   +8 more
wiley   +1 more source