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Enzim L-asparaginase (E.C 3.5.1.1) adalah protein tetramer yang termasuk dalam kelompok keluarga amidohydrolases homolog. ). L-asparaginase secara selektif menghidrolisis L-aspargin (L-Asn) menjadi amonia (NH3) dan asam aspartat. Penelitian ini bertujuan
Asep Awaludin Prihanto +3 more
doaj +1 more source
L-Asparaginase-Based Biosensors [PDF]
L-asparaginase (ASNase) is an aminohydrolase enzyme widely used in the pharmaceutical and food industries. Although currently its main applications are focused on the treatment of lymphoproliferative disorders such as acute lymphoblastic leukemia (ALL) and acrylamide reduction in starch-rich foods cooked at temperatures above 100 °C, its use as a ...
João C. F. Nunes +7 more
openaire +3 more sources
Telah dilakukan penelitian tentang isolasi enzim L-asparaginase yang berasal dari kunyit putih (Curcuma mangga Vall) dan uji aktifitas pada leukimia tipe K562.
Agustina Arpintasari +2 more
doaj +1 more source
L-asparaginase (EC 3.5.1.1) adalah enzim yang menghidrolisis asam amino L-asparagin menjadi amonia dan asam aspartat. Enzim ini mempunyai manfaat utama dalam bidang farmasi dan industri pangan.
Asep Awaludin Prihanto +2 more
doaj +1 more source
NEW PRODUCTION METHOD OF BACTERIAL L-ASPRAGINASE ENZYME FROM DIFFERENT SOIL ENVIRONMENTS IN EGYPT AS ANTICANCER AGENT [PDF]
Background: Acute lymphoblastic leukemia (ALL) is a hematologic cancer that preponderantly falls out in children betwixt 2 and 10 years of age. L-asparaginase is a constitutional element of management for long-suffering with ALL.
Mohammed Kassab
doaj +1 more source
Isolation and identification of L-asparaginase-producing endophytic fungi from the Asteraceae family plant species of Iran [PDF]
L-asparaginase is an important anticancer enzyme that is used in the first line treatment of acute lymphoblastic leukemia. This study was conducted to isolate L-asparaginase-producing endophytic fungi from medicinal plants of family Asteraceae.
Sareh Hatamzadeh +6 more
doaj +2 more sources
L-asparaginase merupakan enzim yang mengubah L-asparagin menjadi L-aspartat. L-asparagin dapat dimanfaatkan oleh sel kanker leukemia sebagai salah satu sumber nutrisinya. Penambahan L-asparaginase dapat menghambat pertumbuhan sel kanker.
Muzuni Muzuni +4 more
doaj +1 more source
Recombinant L-Asparaginase from Zymomonas mobilis: A Potential New Antileukemic Agent Produced in Escherichia coli. [PDF]
L-asparaginase is an enzyme used as a chemotherapeutic agent, mainly for treating acute lymphoblastic leukemia. In this study, the gene of L-asparaginase from Zymomonas mobilis was cloned in pET vectors, fused to a histidine tag, and had its codons ...
Karen Einsfeldt +9 more
doaj +1 more source
Introduction: Cancer is a pervasive disease with different types spreading widely worldwide. Acute lymphoblastic leukemia (ALL) is the bone marrow lymphocyte cancer related to the malignancy of B or T lymphoblast white blood cells.
Masoumeh Massah +3 more
doaj +1 more source
In recent times, exploration of endophytes for L-asparaginase production is gradually gaining momentum. This work deals with studies on the production of L-asparaginase from Talaromyces pinophilus, an endophytic fungus isolated from the rhizomes of ...
Prajna Rao Krishnapura +1 more
core +1 more source

