Results 201 to 210 of about 73,863 (280)

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Rumen microbiota-host interactions regulate intramuscular fat deposition in cattle via the alpha-linolenic acid-fatty acid β-oxidation/L-carnitine-MPO axis. [PDF]

Microbiome
Zhang WT, Wang ML, Liu CY, Li C, He XP, Wang HB, Zan LS, Cheng G.   +7 more
europepmc   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, Volume 13, Issue 16, 18 March 2026.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Punicalagin is the key pomegranate polyphenol inhibiting gut microbial trimethylamine (TMA) production from L-carnitine in an <i>in vitro</i> human colon model.

Food Funct
Haarhuis JE, Gamal El-Din MI, Lamprinaki D, Kroon PA.   +3 more
europepmc   +1 more source

The Effect of L-Carnitine Supplementation in Culture Medium on the Development and Cryopreservation of in Vitro Produced Bovine Embryos. [PDF]

Vet Med Sci
Yildiz M, Cetin Y.
europepmc   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, Volume 13, Issue 16, 18 March 2026.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

Extending dynamic and operational range of the biosensor responding to l-carnitine by directed evolution. [PDF]

Synth Syst Biotechnol
Li T, Dong H, Li J, Wang H, Pu C, Chen S, Yang Z, Ren X, Liu X, Jin Z, Zhang D.   +10 more
europepmc   +1 more source

CA IX Inhibition by a Sulfonamide Compound: A Therapeutic Approach Against Breast Cancer

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
Synergistic Efficacy of MMH‐I and 5‐Fluorouracil Combination Therapy in CA IX‐Expressing Breast Cancer Models: Pathological and Metabolic Insights. ABSTRACT Carbonic anhydrase IX (CA IX) is overexpressed in many solid tumors, contributing to cancer cell proliferation, survival, invasion, and metastasis.
Sükrü Akmese, Ebru Temiz, Elif Gürel, Ismail Koyuncu, Mustafa Durgun, Muhammet Emin Guldur, Kadir Egi, Beyza Ozerol   +7 more
wiley   +1 more source

Addition of Multi‐Level Technologies to Evaluate Eggs and Embryos and Improve Endometrial Quality Applied for In Vitro Fertilization to Achieve Pregnancy: A Case Study

Clinical Case Reports, Volume 14, Issue 3, March 2026.
This integrated clinical approach optimizes the reproductive cycle in several steps, starting with nutrition (A): restricting carbohydrates and inducing ketosis to reduce inflammation and improve insulin sensitivity, which benefits follicular development.
Tania G. Rojas‐Pérez, Yúvika Reyes‐Albarracín, Ginna Ortiz, Juan José Suárez, Diego Vilchis Reyes, Jacqueline Cordero Oropeza, Dinorah Hernández‐Melchor, Esther López‐Bayghen   +7 more
wiley   +1 more source