Results 31 to 40 of about 13,200,542 (201)

Antioxidative Characteristics of Chicken Breast Meat and Blood after Diet Supplementation with Carnosine, L-histidine, and β-alanine

Antioxidants, 2020
The objective of the study was to test the effect of diets supplemented with β-alanine, L-histidine, and carnosine on the histidine dipeptide content and the antioxidative status of chicken breast muscles and blood. One-day-old Hubbard Flex male chickens
Wieslaw Kopec, Dorota Jamroz, Andrzej Wiliczkiewicz, Ewa Biazik, Anna Pudlo, Malgorzata Korzeniowska, Tomasz Hikawczuk, Teresa Skiba   +7 more
doaj   +1 more source

Carnosine Supplementation Enhances Post Ischemic Hind Limb Revascularization

Frontiers in Physiology, 2019
High (millimolar) concentrations of the histidine containing dipeptide – carnosine (β-alanine-L-histidine) are present in the skeletal muscle. The dipeptide has been shown to buffer intracellular pH, chelate transition metals, and scavenge lipid ...
Adjoa A. Boakye, Deqing Zhang, Deqing Zhang, Luping Guo, Luping Guo, Yuting Zheng, Yuting Zheng, David Hoetker, David Hoetker, Jingjing Zhao, Jingjing Zhao, Dheeraj Kumar Posa, Dheeraj Kumar Posa, Chin K. Ng, Huaiyu Zheng, Amit Kumar, Vijay Kumar, Michael F. Wempe, Aruni Bhatnagar, Aruni Bhatnagar, Daniel J. Conklin, Daniel J. Conklin, Shahid P. Baba, Shahid P. Baba   +23 more
doaj   +1 more source

Carnosine quenches the reactive carbonyl acrolein in the central nervous system and attenuates autoimmune neuroinflammation

Journal of Neuroinflammation, 2021
Background Multiple sclerosis (MS) is a chronic autoimmune disease driven by sustained inflammation in the central nervous system. One of the pathological hallmarks of MS is extensive free radical production. However, the subsequent generation, potential
Jan Spaas, Wouter M. A. Franssen, Charly Keytsman, Laura Blancquaert, Tim Vanmierlo, Jeroen Bogie, Bieke Broux, Niels Hellings, Jack van Horssen, Dheeraj Kumar Posa, David Hoetker, Shahid P. Baba, Wim Derave, Bert O. Eijnde   +13 more
doaj   +1 more source

Carnosine-Modified Fullerene as a Highly Enhanced ROS Scavenger for Mitigating Acute Oxidative Stress

, 2020
Fullerenes are known as highly efficient scavengers for reactive oxygen species (ROSs). In this study, a carnosine-modified fullerene derivative (C60–Car) was synthesized via a one-step nucleophilic addition reaction.
Yen Wei (1396648), Haijun Ma (809489), Jiajia Zhao (537913), Danning Hu, Yue Zhou (71752), Haibing Meng, Yue Zhou, Haijun Ma, Xiaoyan Zhang (50085), Jie Li, Xiaoyan Zhang, Jinying Yuan (2285431), Chunru Wang, Danning Hu (3222912), Jinying Yuan, Chunru Wang (1472767), Haibing Meng (4867693), Jiajia Zhao, Jie Li (15030), Yen Wei   +19 more
core   +1 more source

Influences of Beta-Alanine and l-Histidine Supplementation on Growth Performance, Meat Quality, Carnosine Content, and mRNA Expression of Carnosine-Related Enzymes in Broilers

Animals, 2021
The current study investigated the effect of dietary l-histidine and beta-alanine supplementation on growth performance, meat quality, carnosine content, and gene expression of carnosine-related enzymes in broilers.
Bo Qi, Jing Wang, Meng Hu, Youbiao Ma, Shugeng Wu, Guanghai Qi, Kai Qiu, Haijun Zhang   +7 more
doaj   +1 more source

Anti-Cancer Effects of Carnosine—A Dipeptide Molecule

Molecules, 2021
Background: Carnosine is a dipeptide molecule (β-alanyl-l-histidine) with anti-inflammatory, antioxidant, anti-glycation, and chelating properties. It is used in exercise physiology as a food supplement to increase performance; however, in vitro evidence
Monica D. Prakash, Sarah Fraser, Jennifer C. Boer, Magdalena Plebanski, Barbora de Courten, Vasso Apostolopoulos   +5 more
doaj   +1 more source

Recombinant Cystobasidium minutum Aminopeptidase DmpA Efficiently Catalyzes the Production of L-Carnosine

Shipin gongye ke-ji
This experiment investigated the ability of an aminopeptidase gene dmpA from microcyst basidiomycete MCA 4210 (Cystobasidium minutum MCA 4210) to catalyze the synthesis of L-carnosine, and constructed a genetically engineered strain to catalyze the ...
Xiaoxuan SUN, Ruijie ZHANG, Wen SUN, Lingyu CHEN, Xianfeng ZHU, Baoguo ZHANG   +5 more
doaj   +1 more source

Central administration of dipeptides, beta-alanyl-BCAAs, induces hyperactivity in chicks

BMC Neuroscience, 2007
Background Carnosine (β-alanyl-L-histidine) is a putative neurotransmitter and has a possible role in neuron-glia cell interactions. Previously, we reported that carnosine induced hyperactivity in chicks when intracerebroventricularly (i.c.v ...
Denbow D Michael, Morishita Koji, Asechi Mari, Tomonaga Shozo, Tsuneyoshi Yousuke, Furuse Mitsuhiro   +5 more
doaj   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

Advanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao, Yuting Liu, Xiao Huang, Liwen Zhao, Chunli Li, Yongwei Huang   +5 more
wiley   +1 more source

Estimation of Plasma Concentration of L-Carnosine and its Correlation with Core Symptoms of Autism Spectrum Disorder Children: A Pilot Clinical Trial

Frontiers in Bioscience-Landmark
Background: Literature indicates that L-carnosine may be deficient in autism spectrum disorder (ASD) children. The aim of the present study was to estimate the level of L-carnosine in plasma and correlate it with the Autism Treatment ...
Debi Ann Abraham, Udayakumar Narasimhan, Vijayakumar Thangavel Mahalingam, Manikandan Krishnan, Rajanandh Muhasaparur Ganesan, Khang Wen Goh, Ching Siang Tan, Long Chiau Ming, Chrismawan Ardianto   +8 more
doaj   +1 more source