Results 41 to 50 of about 31,622 (258)

l-Citrulline ameliorates cerebral blood flow during cortical spreading depression in rats: Involvement of nitric oxide- and prostanoids-mediated pathway

Journal of Pharmacological Sciences, 2017
l-Citrulline is a potent precursor of l-arginine, and exerts beneficial effect on cardiovascular system via nitric oxide (NO) production. Migraine is one of the most popular neurovascular disorder, and imbalance of cerebral blood flow (CBF) observed in ...
Yuki Kurauchi, Koichi Mokudai, Asami Mori, Kenji Sakamoto, Tsutomu Nakahara, Masahiko Morita, Ayako Kamimura, Kunio Ishii   +7 more
doaj   +1 more source

Administration of L-citrulline prevents Plasmodium growth by inhibiting/ modulating T-regulatory cells during malaria pathogenesis

Journal of Vector Borne Diseases, 2022
Background & objectives: Malaria affects around 228 million people all over the globe. Malaria causing parasite Plasmodium infection leads to activation of immune responses. The growth of parasite and immune activation requires semi essential amino acids
Vikky Awasthi, Rubika Chauhan, Jyoti Das
doaj   +1 more source

Characteristics of L-citrulline transport through blood-brain barrier in the brain capillary endothelial cell line (TR-BBB cells)

Journal of Biomedical Science, 2017
Background L-Citrulline is a neutral amino acid and a major precursor of L-arginine in the nitric oxide (NO) cycle. Recently it has been reported that L-citrulline prevents neuronal cell death and protects cerebrovascular injury, therefore, L-citrulline ...
Kyeong-Eun Lee, Young-Sook Kang
doaj   +1 more source

Citrulline in the management of patients with urea cycle disorders

Orphanet Journal of Rare Diseases, 2023
Background Treatment recommendations for urea cycle disorders (UCDs) include supplementation with amino acids involved in the urea cycle (arginine and/or citrulline, depending on the enzyme deficiency), to maximize ammonia excretion through the urea ...
Apolline Imbard, Juliette Bouchereau, Jean-Baptiste Arnoux, Anaïs Brassier, Manuel Schiff, Claire-Marine Bérat, Clément Pontoizeau, Jean-François Benoist, Constant Josse, François Montestruc, Pascale de Lonlay   +10 more
doaj   +1 more source

Citrullination – small change with a great consequence [PDF]

, 2013
Citrullination is one of the possible post-translational modifications of proteins. It is based on a conversion of L-arginine residue (L-Arg) to L-citrulline residue (L-Cit). The reaction is catalyzed by peptidylarginine deiminases (PAD). The change of L-
Gogól Mariusz
core   +1 more source

Ornithine decarboxylase activity, a clinical biomarker for evaluating cancer chemopreventive efficacy of phytomolecules [PDF]

, 2011
Biomarkers of cancer have made a strong traipse in predicting the disease pattern and contributed significantly to the understanding of tumour state, progression, characteristics and response to therapies.
Nusrat Masood, Suaib Luqman, Vijaya Dubey   +2 more
core   +2 more sources

Human renal and systemic hemodynamic, natriuretic, and neurohumoral responses to different doses of L-NAME [PDF]

, 1998
Experimental evidence indicates that the renal circulation is more sensitive to the effects of nitric oxide (NO) synthesis inhibition than other vascular beds. To explore whether in men the NO-mediated vasodilator tone is
Boomsma, F. (Frans), Broere, A., Derkx, F.H.M. (Frans), Man in 't Veld, A.J. (Arie), Meiracker, A.H. (Anton) van den, Schalekamp, M.A.D.H. (Maarten)   +5 more
core   +5 more sources

l-Citrulline Protects from Kidney Damage in Type 1 Diabetic Mice [PDF]

Frontiers in Immunology, 2013
Diabetic nephropathy (DN) is a major cause of end-stage renal disease, associated with endothelial dysfunction. Chronic supplementation of l-arginine (l-arg), the substrate for endothelial nitric oxide synthase (eNOS), failed to improve vascular function.
Maritza J Romero, Maritza J Romero, Maritza J Romero, Lin eYao, Supriya eSridhar, Anil eBhatta, Huijuan eDou, Ganesan eRamesh, Ganesan eRamesh, Michael W Brands, David M Pollock, David M Pollock, Ruth B Caldwell, Ruth B Caldwell, Ruth B Caldwell, Stephen D Cederbaum, C Alvin eHead, Zsolt eBagi, Rudolf eLucas, Rudolf eLucas, Rudolf eLucas, Robert William Caldwell, Robert William Caldwell   +22 more
openaire   +3 more sources

Consumption of watermelon juice enriched in L-citrulline and pomegranate ellagitannins enhanced metabolism during physical exercise [PDF]

, 2017
L-Citrulline is a nonessential amino acid precursor of arginine and indirectly a precursor of nitric oxide (NO), which is a vasodilator and increases mitochondrial respiration.
Aguayo, Encarna, Alacid, Fernando, Fernández Lobato, Bárbara, Martínez Sánchez, Ascensión, Ramos Campo, Domingo Jesús, Rubio Arias, Jacobo Ángel   +5 more
core   +2 more sources

Citrulline Accumulation Mechanism of Pediococcus acidilactici and Weissella confusa in Soy Sauce and the Effects of Phenolic Compound on Citrulline Accumulation

Frontiers in Microbiology, 2021
Citrulline is one of the major precursors of ethyl carbamate in soy sauce, and the accumulation of citrulline is attributed to the metabolism of arginine by bacteria with the arginine deiminase (ADI) pathway.
Kai Zhou, Kai Zhou, Kai Zhou, Xiao Zhang, Bingyong Li, Chaoqun Shen, Yuan-Ming Sun, Jianyuan Yang, Zhen-Lin Xu   +8 more
doaj   +1 more source