Results 71 to 80 of about 30,868 (223)

Alterations in serum amino acid concentrations in dogs with protein-losing enteropathy [PDF]

, 2018
BackgroundCertain amino acids are decreased in humans with inflammatory bowel disease (IBD) and supplementation with the same amino acids has shown beneficial effects in animal models of IBD.
Allenspach, Beeken, Bettenworth, Clayton, Coburn, Dąbrowski, Gupta, Hashimoto, Hou, Kim, Kim, Li, Liu, Liu, Middleton, Morgan, Nikolaus, Ren, Richard, Ruth, Schrocksnadel, Tsune, Walser, Wang, Widner, Xin   +25 more
core   +4 more sources

Characteristics of L-Citrulline Transport across Rat Small Intestine In Vitro [PDF]

Pediatric Research, 1992
The amino acid L-citrulline is an important intermediate of urea cycle and a key precursor for arginine biosynthesis. We have examined the characteristics of citrulline transport across the everted sacs of the rat small intestine. Our studies suggest that the optimal site of citrulline absorption is middle to lower ileum. It shows active transport, and
J V, Vadgama, D F, Evered
openaire   +2 more sources

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source

Thẩm định quy trình định lượng L-citrulline trong một số loại dưa hấu bằng phương pháp UV-Vis

Tạp chí Khoa học Đại học Cần Thơ
Dưa hấu là một loại trái cây giàu L-citrulline, đặc biệt là trong vỏ quả, L-citrulline giúp cải thiện sức khỏe tim mạch, tăng cường miễn dịch và các lợi ích về sức khỏe tình dục.
Vi Nhã Trân, Trương Huỳnh Anh, Phạm Thúy Nguyên, Nguyễn Thị Hoàng Oanh, Nguyễn Ngọc Trang Thùy, Trần Thị Minh Thư, Lại Quốc Đạt   +6 more
doaj   +1 more source

Mitokondriális eredetű nitrogén szabadgyökök és ATP-függő K-csatornák szerepe az organellum működésében = The involvement of mitochondrial-derived nitrogen radicals and mitoK-ATP channels in the regulation of organelle function [PDF]

, 2009
Elsőként a mitoKATP csatornák alegységeit terveztük azonosítani humán szív mintákon. A kísérletek során megbizonyosodtunk afelől, hogy a korábban ilyen csatornáknak gondolt fehérjék nincsenek jelen megfelelő számban és formában a mitokondriális ...
Csordás, Attila, Horváth, Eszter Mária, Lacza, Zsombor, Pankotai, Eszter, Szabó, Csaba   +4 more
core  

Reduction of Ribonucleotide Reductase Subunit RRM2 Potentially Impairs Gut Function of Woody Breast Broilers

Animal Research and One Health, EarlyView.
Woody breast compromises meat quality leading to reduced consumer appeal. Although its causes are unclear, improvements observed with certain dietary supplements suggest that gut health may influence woody breast development. Ribonucleotide reductase subunit RRM2 is vital for mitochondrial function and gastrointestinal integrity, and alteration in its ...
Majid Shakeri, Elizabeth Ziabtchenko, Janghan Choi, Caitlin E. Harris, Richard J. Buhr, Trevor R. Mitchell, Byungwhi Kong, Hong Zhuang, Brian Bowker   +8 more
wiley   +1 more source

Vascular Function Intervention Trial in sickle cell disease (V-FIT): Trial Protocol [PDF]

, 2014
This protocol outlines procedures for capturing participant information as part of the V-FIT study. The protocol should not be used as a guide for the treatment of other participants; every care was taken in its drafting, but corrections or amendments ...
Cox, Sharon, Halcox, Julian, Kamala, Beatrice Abella, Prentice, Andrew   +3 more
core  

Synthetic Cathepsin B Sensitive Adjuvant‐Peptide Conjugates to Target Intracellular Toll‐Like Receptors 7 and 8

ChemistryEurope, EarlyView.
Cathepsin B‐sensitive peptide–adjuvant conjugates are designed, synthesized, and evaluated to deliver an antigenic peptid and an adjuvant targeting Toll‐like receptors 7 and 8 (TLR7/8) to antigen presenting cells. The adjuvant is released by cathepsin B resulting in antigen presentation and TLR mediated T cell activation.
Marjolein M. E. Isendoorn, Giulia Castello, Nico J. Meeuwenoord, Martijn Verdoes, Jeroen D. C. Codée, Ferry Ossendorp, Dmitri V. Filippov   +6 more
wiley   +1 more source

Cross-sectional observational study of 208 patients with non-classical urea cycle disorders. [PDF]

, 2014
Urea cycle disorders (UCDs) are inherited disorders of ammonia detoxification often regarded as mainly of relevance to pediatricians. Based on an increasing number of case studies it has become obvious that a significant number of UCD patients are ...
Ballhausen, D., Baumgartner, M.R., Beblo, S., Burgard, P., Das, A., Gautschi, M., Glahn, E.M., Grünert, S.C., Hennermann, J., Hochuli, M., Huemer, M., Häberle, J., Karall, D., Kölker, S., Lachmann, R.H., Lindner, M., Lotz-Havla, A., Möslinger, D., Nuoffer, J.M., Plecko, B., Rutsch, F., Rüegger, C.M., Santer, R., Spiekerkoetter, U., Staufner, C., Stricker, T., Wijburg, F.A., Williams, M.   +27 more
core   +3 more sources

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source