Results 151 to 160 of about 11,907 (183)

Versatile and Valuable Utilization of Amidohydrolase L-glutaminase in Pharma and Food industries: A Review

Current Drug Metabolism, 2020
L-glutaminase has versatile applications in pharma and food industries. In pharmaceutical industry, L-glutaminase can be used as anti-oxidant and anti-cancer agent to treat Acute Lymphocytic Leukaemia (ALL). Whereas, in the food industry, L-glutaminase is used for acrylamide degradation, theanine production, flavour enhancer, soy sauce and many.
Chandrasai Potla Durthi, Madhuri Pola, Satish Babu Rajulapati, Anand Kishore Kola, Mohammad Amjad Kamal   +4 more
openaire   +2 more sources

In silicoAnalysis of L-Glutaminase from Extremophiles

Current Proteomics, 2019
Background:L-glutaminase enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. Protein L-glutaminase, which converts amino acid glutamine to a glutamate residue, is useful as antileukemic agent, antiretroviral agent and a new food-processing enzyme.Objective:The ...
Sarita Devi, null Savitri, Tilak Raj, Nikhil Sharma, Wamik Azmi   +4 more
openaire   +1 more source

L-Glutaminase and L-Asparaginase by Extracorporeal Route in Acute Lymphoblastic Leukemia Therapy

The International Journal of Artificial Organs, 1981
Use of L-asparaginase by the extracorporeal route in the therapy of acute lymphoblastic leukemia (ALL) has been proposed. Results, however, are not so satisfactory as i.v. administration of this enzyme, because the levels of L-asparagine do not fall for a sufficient length of time due to the antagonistic action of the L-asparagine ...
C, Giordano, R, Esposito, G, Mazzola, G, Vecchio, M, Pluvio, D, Cirillo, G B, Capasso, G, Buonanno   +7 more
openaire   +2 more sources

PRODUCTION AND OPTIMIZATION OF L-GLUTAMINASE ENZYME FROMHypocrea jecorinaPURE CULTURE

Preparative Biochemistry and Biotechnology, 2013
L-Glutaminase (L-glutamine amidohydrolase, EC 3.5.1.2) is the important enzyme that catalyzes the deamination of L-glutamine to L-glutamic acid and ammonium ions. Recently, L-glutaminase has received much attention with respect to its therapeutic and industrial applications.
Bülbül, Dilara, KARAKUŞ, Emine
openaire   +3 more sources

Optimization of L-glutaminase production by Penicillium chrysogenum

THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Botany), 2021
Hamed Shora, Metwally Metwally, Mohammed Zaki   +2 more
openaire   +1 more source

Recent developments in l-glutaminase production and applications - An overview.

Bioresource technology, 2018
l-glutaminases is an important industrial enzyme which finds potential applications in different sectors ranging from therapeutic to food industry. It is widely distributed in bacteria, actinomycetes, yeast and fungi. l-Glutaminases are mostly produced by Bacillus and Pseudomonas sp.
Parameswaran, Binod, Raveendran, Sindhu, Aravind, Madhavan, Amith, Abraham, Anil Kuruvilla, Mathew, Ummalyma Sabeela, Beevi, Rajeev K, Sukumaran, Sudhir P, Singh, Ashok, Pandey   +8 more
openaire   +1 more source

Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer

Cell Metabolism, 2022
Darren Creek, Sarah Best, Axel Kallies   +2 more
exaly  

Combinatorial engineering for efficient production of protein-glutaminase in Bacillus subtilis

Enzyme and Microbial Technology, 2021
Guoqiang Zhang, Guocheng Du, Zhou Jw
exaly  

Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly

Cell Metabolism, 2020
Ruben Rodríguez Agudo, Erica Villa, BEATRIZ Gómez-Santos   +2 more
exaly  

L-Glutaminase as a Therapeutic Enzyme of Microbial Origin

2005
Abdulhameed Sabu, K. Madhavan Nampoothiri, Ashok Pandey   +2 more
openaire   +1 more source