Results 141 to 150 of about 13,194,872 (182)
Production, Purification and Applications of Microbial L-Glutaminase
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Effect of Soil Temperature, Moisture and pH on Soil L-glutaminase Activity
G. Pavani +3 more
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PRODUCTION AND OPTIMIZATION OF L-GLUTAMINASE ENZYME FROMHypocrea jecorinaPURE CULTURE
L-Glutaminase (L-glutamine amidohydrolase, EC 3.5.1.2) is the important enzyme that catalyzes the deamination of L-glutamine to L-glutamic acid and ammonium ions. Recently, L-glutaminase has received much attention with respect to its therapeutic and industrial applications.
Bülbül, Dilara, KARAKUŞ, Emine
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L-Glutaminase and L-Asparaginase by Extracorporeal Route in Acute Lymphoblastic Leukemia Therapy
Use of L-asparaginase by the extracorporeal route in the therapy of acute lymphoblastic leukemia (ALL) has been proposed. Results, however, are not so satisfactory as i.v. administration of this enzyme, because the levels of L-asparagine do not fall for a sufficient length of time due to the antagonistic action of the L-asparagine ...
C, Giordano +7 more
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The role of glutaminase in cancer [PDF]
Increased glutamine metabolism (glutaminolysis) is a hallmark of cancer and is recognised as a key metabolic change in cancer cells. As a heterogeneous disease with different morpholog- ical and molecular subtypes and response to therapy, breast cancer ...
Andrew Green +2 more
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Marine microbial L-glutaminase: from pharmaceutical to food industry
Applied Microbiology and Biotechnology, 2021Deamination of L-glutamine to glutamic acid with the concomitant release of ammonia by the activity of L-glutaminase (L-glutamine amidohydrolase EC 3.5.1.2) is a unique reaction that also finds potential applications in different sectors ranging from therapeutics to food industry.
Noora Barzkar +4 more
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l-glutaminase activity of soils
Soil Biology and Biochemistry, 1991Abstract l -Glutaminase [ l -glutamine amidohydrolasc, EC 3.5.1.2] catalyzes the hydrolysis of l -glutamine to produce ammonia and l -glutamic acid. We have detected this enzyme in soils. A simple, precise, rapid and sensitive method to assay its activity is described, which involves determination of the NH+4 released by l -glutaminase activity ...
W.T. Frankenberger, M.A. Tabatabai
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Applied Microbiology and Biotechnology, 2022
Because of the therapeutical impacts of hydrolytic enzymes in different diseases, in particular malignancies, we aimed to produce a recombinant putative L-glutaminase (GLS ASL-1) from a recently characterized halo-thermotolerant Bacillus sp. SL-1.
Shayan Simay +5 more
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Because of the therapeutical impacts of hydrolytic enzymes in different diseases, in particular malignancies, we aimed to produce a recombinant putative L-glutaminase (GLS ASL-1) from a recently characterized halo-thermotolerant Bacillus sp. SL-1.
Shayan Simay +5 more
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Purification and physicochemical properties of l-glutaminase from Pseudomonas
Biochimica et Biophysica Acta (BBA) - Enzymology, 1972Abstract Crystalline l -glutaminase ( l -glutamine amidohydrolase, EC 3.5.1.2) was obtained from Pseudomonas and its homogeneity was confirmed by electrophoresis and ultracentrifugal analysis. The specific activity of the enzyme was 36 I.U. per mg of protein for l -glutaminase action and 15 I.U.
H, Katsumata +4 more
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Factors affecting l-glutaminase activity in soils
Soil Biology and Biochemistry, 1991Abstract l -Glutaminase activity in soil profile samples decreased with sample depth. The relationship between l -glutaminase activity and organic C. using the pooled data (33 samples) from five soil profiles, was highly correlated ( r = 0.92 ∗∗ ).
W.T. Frankenberger, M.A. Tabatabai
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