Results 51 to 60 of about 13,429,421 (274)

Influence of Dietary Histidine, Hybrid Line and Gender on Chicken Meat Quality and Carnosine Concentration

open access: yesThe Journal of Poultry Science, 2015
The aim of the investigation was to determine influence of L-histidine dietary supplementation (P1 0.0%, P2 0.1%, P3 0.2% and P4 0.3%), hybrid line (Cobb 500 and Hubbard Classic) and gender on meat quality and carnosine concentration in chicken breast ...
Gordana Kralik   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

FERMENTATIVE PRODUCTION OF L-HISTIDINE

open access: yesThe Journal of General and Applied Microbiology, 1971
Mutant strains of Brevibacterium flavum, Brevibacterium lactofermentum, and Corynebacterium acetoacidophilum which resist 2-thiazole alanine and require arginine, methionine, tryptophan, leucine, phenylalanine, lysine, threonine, uracil, xanthine, and/or shikimic acid for their growth produce much more histidine by fermentation of otherwise ...
KOJI KUBOTA, TERUO SHIRO, SHINJI OKUMURA
openaire   +3 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Inhibitors of Mycobacterium tuberculosis EgtD target both substrate binding sites to limit hercynine production

open access: yesScientific Reports, 2021
Ergothioneine (EGT) is a low molecular weight histidine betaine essential in all domains of life but only synthesized by selected few organisms. Synthesis of EGT by Mycobacterium tuberculosis (M.
Thanuja D. Sudasinghe   +2 more
doaj   +1 more source

EFFECT OF EXCESS L-HISTIDINE DIET ON ACCUMULATION OF L-HISTIDINE IN ISOLATED RAT SMALL INTESTINE

open access: yesJournal of Nutritional Science and Vitaminology, 1974
Effects of protein deprivation and excessive administration of L-histidine on the accumulation of L-histidine in rat small intestine in vitro were investigated using tissue strips and rings. Compared with a 20% casein diet, a non-protein diet and a 5% casein + 5% L-histidine diet significantly enhanced the accumulation of L-histidine per unit wet ...
NAKAMURA, Yukio   +2 more
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Beyond rational—biosensor-guided isolation of 100 independently evolved bacterial strain variants and comparative analysis of their genomes

open access: yesBMC Biology, 2023
Background In contrast to modern rational metabolic engineering, classical strain development strongly relies on random mutagenesis and screening for the desired production phenotype.
Philipp T. Baumann   +8 more
doaj   +1 more source

Quantitative Analysis of Histidine Amino Acid as a Predictor of Ergothioneine in the Drying and Frying Process of White Oyster Mushrooms (Pleurotus ostreatus)

open access: yesAmerta Nutrition, 2021
Backgrounds: White oyster mushroom (Pleurotus ostreatus) is widely cultivated by Indonesian people due to its delicious and nutritious taste. Pleurotus ostreatus contains 18 amino acids that make up the body and antioxidants, including phenolic compounds
Dilla Dayanti   +3 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

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