Results 61 to 70 of about 13,429,421 (274)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Synthesis, Characterization and Stereoselective Catalytic Oxidations of Chelated Deuterohaemin-Glycyl-L-Histidine Complexes

, 1998
The manuscript reports on the synthesis and characterization of a series of chelated deuterohaemin-glycyl-L-histidine Complexes. They are able to perform stereoselective catalytic oxidations of phenols in the presence of hydrogen peroxide.
Chillemi F., CASELLA, LUIGI, De Gioia L., Favretto M., Gullotti M., MONZANI, ENRICO, Linati L.   +6 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Modular systems metabolic engineering enables balancing of relevant pathways for l-histidine production with Corynebacterium glutamicum

Biotechnology for Biofuels, 2019
Background l-Histidine biosynthesis is embedded in an intertwined metabolic network which renders microbial overproduction of this amino acid challenging. This is reflected in the few available examples of histidine producers in literature.
Andreas Schwentner, André Feith, Eugenia Münch, Judith Stiefelmaier, Ira Lauer, Lorenzo Favilli, Christoph Massner, Johannes Öhrlein, Bastian Grund, Andrea Hüser, Ralf Takors, Bastian Blombach   +11 more
doaj   +1 more source

Cellular transport of l-histidine in Hartnup disease [PDF]

Journal of Clinical Investigation, 1969
The urinary excretion, the intestinal absorption, and the elimination of histidine from blood were studied in two patients with Hartnup disease. On standard diet the patients lost a great proportion of the dietary histidine in the urine, whereas the fecal loss was negligible.
S, Halvorsen, O, Hygstedt, R, Jagenburg, O, Sjaastad   +3 more
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

L-histidine imprinted synthetic receptor for biochromatography applications

, 2006
WOS: 000241219800025PubMed ID: 17037929We have proposed novel surface-imprinted beads for selective separation of cytochrome c (cyt c) by N-methacryloyl(L)-histidine-copper(II) [MAH-Cu(II)] as a new metal-chelating monomer via metal coordination ...
Say, Ridvan, Oezcan, Ayca Atilir, Ersoez, Arzu, Özcan, Ayça Atılır, Say, Rıdvan, Denizli, Adil, Ersöz, Arzu   +6 more
core   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Effect of precursor amino acids for carnosine synthesis on breast fiber microstructures and myofiber differentiation-related gene expression in slow-growing chicken [PDF]

Animal Bioscience
Objective The effects of carnosine synthesis on the structural and microstructural determinants of meat quality have not been studied to date. Therefore, this study aimed to investigate the effect of supplementation with carnosine synthesis precursors on
Cindy Riou, Panpradub Sinpru, Chanadda Suwanvichanee, Boonyarit Kamkrathok, Chalermluck Phoovasawat, Catleya Rojviriya, Wittawat Molee, Amonrat Molee   +7 more
doaj   +1 more source

Proton magnetic relaxation mechanisms and solution dynamics of L-histidine

, 1983
Longitudinal and transverse proton relaxation rates have been measured for L-histidine in water solution. From a comparison of the former, measured in the selective and non-selective modes, it was found that the dipolar relaxation mechanism dominates the
Pogliani L., Rossi C., Laschi F., Niccolai N.   +3 more
core   +1 more source