Results 91 to 100 of about 312,266 (316)

Ischemic Myocardium Targeting Peptide‐Guided Nanobubbles for Multimodal Imaging and Treatment of Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Nanobubbles functionalized with indocyanine green and ischemic myocardium‐targeting peptide effectively target cardiomyocytes and enable the multimodal (fluorescence, ultrasonic, and photoacoustic) imaging of ischemic myocardium in mice with coronary microvascular dysfunction (CMD).
Bo Yu, Ziwei Pang, Jing Zhao, Jingyi Xue, Hsuan Lo, Tiancheng Gu, Ping Zhang, Jiawei Tian, Guo‐Qing Du   +8 more
wiley   +1 more source

Advanced Materials for Biological Field‐Effect Transistors (Bio‐FETs) in Precision Healthcare and Biosensing

Advanced Healthcare Materials, EarlyView.
This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey, Manish Bhaiyya, Prakash Rewatkar, Jitendra B. Zalke, Nitin P. Narkhede, Hossam Haick   +5 more
wiley   +1 more source

Development of Photo‐Biocatalytic Redox System for Asymmetric Synthesis of Optically Active Amines Using Blue Light and Transaminases. A Case Study Toward Mavacamten

Advanced Synthesis &Catalysis, EarlyView.
Abstract α‐Chiral amines are versatile building blocks for the asymmetric synthesis of optically pure high‐added‐value chemicals, including pharmaceuticals, agrochemicals, and natural products. Herein, we report a one‐pot, two‐step sequential deracemization of racemic sec‐alcohols to optically enriched primary amines throught a photo‐biocatalytic ...
Natalia Antos, Aleksandra Rudzka, Anna Hoser, Tamara Reiter, Wolfgang Kroutil, Paweł Borowiecki   +5 more
wiley   +1 more source

A 3D‐Printed Microfluidic Sensor Platform for Online Bioprocess Monitoring

Advanced Sensor Research, EarlyView.
A 3D‐printed microfluidic lab‐on‐a‐chip sensor platform is presented, compatible with various cultivation setups, that integrates sensors for pH, pO₂, pCO₂, glucose, lactate, and additionally features a sampling unit for small‐volume abstraction. With this platform, continuous real‐time monitoring of critical bioprocess parameters is enabled and ...
Christopher Heuer, Anton Enders, Steffen Winkler, Martin Klaßen, Thorsten Teutenberg, Janina Bahnemann   +5 more
wiley   +1 more source

Dual Charge Transfer Mechanisms in Intimately Bonded S‐scheme Heterojunction Photocatalyst with Expeditious Activity toward Environmental Remediation

Advanced Sustainable Systems, EarlyView.
A novel MBOdCN S‐scheme heterojunction photocatalyst is fabricated using pristine Mg‐Bi2O3 and grayish g‐C3N4, where dynamic dual charge migration paths occur to accelerate exciton dissociation. This composite catalyst realizes high degradation efficiency of up to 99.56% of oxytetracycline (OTC) removal under optimized conditions. The material exhibits
Potlako J. Mafa, Mope E. Malefane, Francis Opoku, Adewale O. Oladipo, Gcina Mamba, Tunde L. Yusuf, Jemal Fito Nure, Sogolo L. Lebelo, Dan Liu, Jianzhou Gui, Bhekie B. Mamba, Alex T. Kuvarega   +11 more
wiley   +1 more source

Shrimp Virus Regulates ROS Dynamics via the Nrf2 Pathway to Facilitate Viral Replication

Advanced Science, EarlyView.
Viruses manipulate host ROS as a strategy to achieve successful infection. WSSV exploits Nrf2 pathway to maintain ROS homeostasis and establishes a positive feedback loop to facilitate WSSV replication. Wsv220 competitively binds to Keap1 to activate Nrf2. Nrf2 up‐regulates LvG6PDH to produce more NADPH and GSH to eliminate excessive ROS.
Honghui He, Kai Yuan, Junming Pan, Shaoping Weng, Chaozheng Li, Yihong Chen, Jianguo He   +6 more
wiley   +1 more source

Recombinant production, purification, and biochemical characterization of a novel L-lactate dehydrogenase from Bacillus cereus NRC1 and inhibition study of mangiferin. [PDF]

Front Bioeng Biotechnol, 2023
Esa SS, El-Sayed AF, El-Khonezy MI, Zhang S.   +3 more
europepmc   +1 more source

AKT1 Phosphorylates FDX1 to Promote Cuproptosis Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study demonstrates that copper activates the AKT signaling pathway, which inhibits ferredoxin‐1 (FDX1), a key regulator of cuproptosis. AKT1‐mediated FDX1 phosphorylation not only abrogates FDX1‐induced cuproptosis and aerobic respiration but also promotes glycolysis.
Zicheng Sun, Huazhen Xu, Guanming Lu, Ciqiu Yang, Xinya Gao, Jing Zhang, Xin Liu, Yongcheng Chen, Kun Wang, Jianping Guo, Jie Li   +10 more
wiley   +1 more source

Enantioselective Biosynthesis of l-Phenyllactic Acid by Whole Cells of Recombinant Escherichia coli

Molecules, 2017
Background: l-Phenyllactic acid (l-PLA)—a valuable building block in the pharmaceutical and chemical industry—has recently emerged as an important monomer in the composition of the novel degradable biocompatible material of polyphenyllactic acid. However,
Yibo Zhu, Ying Wang, Jiayuzi Xu, Jiahao Chen, Limei Wang, Bin Qi   +5 more
doaj   +1 more source

Effects of freezing rate on structural changes in L-lactate dehydrogenase during the freezing process. [PDF]

Sci Rep, 2021
Park H, Park JY, Park KM, Chang PS.
europepmc   +1 more source